Neuroendocrine Neoplasms: Current Challenges and Advances in the Biological Aspects, Diagnostic and Therapeutic Management

Dear Colleagues,

Neuroendocrine neoplasms (NENs) are a heterogeneous group of tumors with increasing incidence and prevalence. NENs clinical management requires a multidisciplinary approach, which has a positive impact on the survival of the patients.

NENs heterogeneity is linked to both biological and clinical characteristics. In recent years, the better understanding of NENs biology and the efforts of different specialists and researchers in investigating NENs treatment and diagnosis strategies have continually evolved NENs management as a field of investigation. As a result, many preclinical studies and phase II and phase III clinical trials have been completed, that have allowed the improvement of the treatment strategy and diagnostic tools for NENs. However, many other studies are ongoing and are expected to further improve our understanding of the biology of NENs as well as treatment and diagnosis.

This Special Issue aims to gather research on the biological, diagnostic, and therapeutic aspects that can offer real progresses in the management of NENs patients. Original research and review articles should present new data from basic or clinical research and/or analyze and discuss previous research in an innovative and original way.

Dr. Salvatore Tafuto
Dr. Alessandro Ottaiano
Dr. Vincenzo Quagliariello
Dr. Claudia von Arx
Guest Editors

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