Molecular Pathways in Metastasis of Lung Cancer

Dear Colleagues,

Lung cancer is the leading cause of cancer related death worldwide. In addition to the histological classification into mainly non-small cell adenocarcinomas and squamous cell carcinomas and small cell lung carcinomas, the growing understanding of oncogenic molecular pathways has led to a pronounced diversification of therapeutic options and thus to a significant improvement in the prognosis of patients. In particular, however, the pronounced tendency to develop distant metastases, especially in the brain, liver, bones and adrenal gland, severely limits the long-term prognosis of affected patients.

In this special issue, the molecular oncogenic pathways in lung cancer metastases will be highlighted from the perspective of basic, translational and clinical research with the overall goal of improving the use of existing therapeutics and identifying new potential drug targets.

Dr. Hanibal Bohnenberger
Guest Editor

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