Thermal Ablation in the Management for Colorectal Liver Metastases

Dear Colleagues,

Targeted minimally invasive, image-guided therapies in the management of patients with colorectal liver metastases (CRLMs) play an increasingly important role in clinical oncology and health care in general. These rapidly evolving treatment modalities (e.g., microwave ablation, irreversible electroporation or stereotactic body radiation therapy) are characterized by the local delivery of (non-)thermal energy or radiation at a high dosage, directly affecting the tumor tissue in order to treat cancer more effectively. Their success is chiefly based on their minimally invasive nature, superior safety and toxicity profile, and often comparable or superior mid- and long-term oncologic outcomes, compared with conventional systemic therapy and surgical resection. The increasing role of minimally invasive, real-time, image-guided and/or navigated treatment techniques for CRLM is the primary topic of this Special Issue. We aim to procure high-quality original research and review articles that address the available kinds of (non-)thermal and radiation-related treatment options for CRLM in order to improve oncological outcomes in interventional and radiation oncology. Reports of studies highlighting the use of real-time image guiding or navigation tools or ablation confirmation techniques for volumetric assessment of the ablation zone are particularly welcome.

Prof. Dr. Martijn Meijerink
Dr. Robbert S. Puijk
Guest Editors

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