Helicases in DNA Repair: From Molecular Mechanisms to Medical and Biotechnological Applications
A special issue of Biomolecules (ISSN 2218-273X).
Deadline for manuscript submissions: 23 December 2025 | Viewed by 8
Special Issue Editor
Special Issue Information
Dear Colleagues,
The international journal Biomolecules (impact factor of 4.8; cite score of 9.4) invites submissions to a Special Issue focused on helicases in DNA repair.
Helicases are a huge group of enzymes that utilizes ATP hydrolysis to unwind nucleic acid duplexes and plays an essential role in almost all aspects of nucleic acid metabolism, such as replication, transcription, and repair. This Special Issue will focus on helicases in DNA repair, which itself is a diverse biological process with different pathways for repairing various DNA damage. Defects in helicases and/or abnormal regulations of helicase expression or action have sever impacts on genome stability. Although helicases have been studied by many scientists worldwide since the middle of last century, new mechanisms of helicase action or even new helicase members continue to emerge. Accordingly, applications of helicases in emerging biotechnologies and medicine continue to grow.
We encourage researchers that are interested in helicases, their role, and/or action in DNA repair, as well as their potential medical or industrial applications, to submit relevant research articles to this Special Issue. In addition, review articles that cover the related research topics and provide concluding remarks will also be considered.
We look forward to your contributions.
Prof. Dr. Li Fan
Guest Editor
Manuscript Submission Information
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Keywords
- DNA unwinding
- DNA damage response
- damage verification
- genetic disease
- premature aging
- cancer
- chemotherapy
- gene therapy
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