Decoding Retinal Degeneration
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: 30 June 2026 | Viewed by 37
Special Issue Editor
Interests: retinitis pigmentosa; inherited retinal degenerations; retinal electrophysiology; low vision; visual rehabilitation; legal ophthalmology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Retinal degeneration encompasses a broad spectrum of hereditary and acquired disorders that lead to progressive visual impairment and, in many cases, irreversible blindness. Despite significant advances in genetics, imaging, and molecular medicine, the precise mechanisms underlying retinal cell dysfunction and death remain only partially understood.
This Special Issue, “Decoding Retinal Degeneration,” aims to provide a multidisciplinary platform for cutting-edge research exploring the molecular, genetic, epigenetic, and clinical aspects of retinal degenerative diseases. We welcome original studies, reviews, and translational research addressing pathophysiology, innovative biomarkers, gene–environment interactions, novel diagnostic tools, and emerging therapeutic strategies—including gene therapy, RNA-based approaches, stem-cell treatments, neuroprotection, and targeted drug delivery.
Our goal is to shed new light on the mechanisms involved in retinal degeneration and foster the development of personalized and precision-based interventions capable of modifying disease progression and improving clinical outcomes. We look forward to receiving your valuable contributions to advance this important and rapidly evolving field.
Dr. Enzo Maria Vingolo
Guest Editor
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Keywords
- retinal degeneration
- inherited retinal diseases
- retinitis pigmentosa
- stargardt disease
- age-related macular degeneration
- photoreceptor degeneration
- gene therapy
- RNA-based therapies
- epigenetic regulation
- transcriptomics/proteomics
- retinal biomarkers
- molecular pathways of neurodegeneration
- oxidative stress and inflammation
- mitochondrial dysfunction
- retinal microglia and neuroinflammation
- retinal vasculopathy
- stem cell therapy
- retinal drug delivery
- nanotechnology in ophthalmology
- advanced retinal imaging (OCT, OCTA, FAF)
- artificial intelligence in retinal disease
- precision and personalized ophthalmology
- translational research in ophthalmology
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