Oxidative Stress in Health and Disease
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cell Biology and Pathology".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 80
Special Issue Editor
Interests: oxidative stress; inflammation; autophagy; metabolic disease; neurodegenerative disease; atherosclerosis; preclinical pharmacology; natural products; flavonoids; cannabinoids; adenosine signaling
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Oxidative stress is caused by an imbalance between the production of oxygen reactive species (ROS), such as superoxide radicals (O2•−), hydrogen peroxide (H2O2), hydroxyl radicals (•OH), and singlet oxygen (1O2), and the ability to neutralize them. The accumulation of ROS leads to cellular damage in metabolism processes, negatively affecting several cellular structures and molecules, such as DNA, lipids, and proteins; this can trigger cell inflammation, apoptosis and necrosis, peroxidation, chromosomal aberration, and damage to lipoproteins, membranes, DNA, collagen structure and mitochondrial function. Moreover, oxidative stress is involved in the initiation and progression of numerous diseases, such as cancer, cardiovascular disease, neurological disease, rheumatoid arthritis and autoimmune diseases. Recent studies have demonstrated that elevated ROS levels induce infertility in males and females, impairing the reproductive system. New therapeutic approaches targeting oxidative stress and its signaling molecules could provide the means to treat various human diseases.
This Special Issue of Biomedicines, “Oxidative Stress in Health and Disease”, aims to compile original research papers and cover new literature data and insights on the pathogenesis, molecular pathways and beneficial effects of novel and safe treatments of oxidative stress.
Dr. Federica Mannino
Guest Editor
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Keywords
- oxidative stress
- inflammation
- human diseases
- apoptosis
- peroxidation
- DNA damage
- mitochondria
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