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Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Current Advances in Cancer Genomics

edited by

Yuanxiang Li

submission deadline 31 Oct 2026 | Viewed by 104 | Submission Open

Keywords: cancer genomics; tumor heterogeneity; epigenomics; single-cell sequencing; multi-omics; genomic biomarkers; precision oncology; computational genomics; non-coding RNA; drug resistance

(This special issue belongs to the Section Cancer Biology)

Pathogenesis and Immune Evasion of Mycobacteria in Mammals

edited by Federico Carlos Blanco and Cristina Lourdes Vázquez

submission deadline 31 Oct 2026 | Viewed by 102 | Submission Open

Keywords: mycobacteria; pathogenesis; immune evasion; host– pathogen interactions; latency; zoonotic transmission; comparative immunology; vaccine development; host-directed therapies

(This special issue belongs to the Section Immunology)

Exploring the Impact of Probiotics and Fermented Food on Gut Microbiota for Personalized Nutrition and Host Health

edited by

Nakphaichit Massalin

submission deadline 31 Oct 2026 | Viewed by 67 | Submission Open

Keywords: probiotics (bacteria and yeast); gut microbiota and mycobiome; personalized nutrition; microbiome– host interaction mechanisms; gut– axis communication (brain/skin/immune)

(This special issue belongs to the Section Microbiology)

Molecular Mechanisms of AHPND: From Pathogen Virulence to Host Immunity

edited by

Sonia A. Soto-Rodriguez

submission deadline 31 Oct 2026 | Viewed by 58 | Submission Open

Keywords: AHPND; Vibrio; pathogenesis; host immunity; shrimp disease; aquaculture; virulence mechanisms; omics

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Research Advances on Biology and Genetics of Bees

edited by

Jiaxing Huang

and

Guiling Ding

submission deadline 31 Oct 2026 | Viewed by 49 | Submission Open

Keywords: bee biology; pollination ecology; environmental stressors; bee genomics and omics; bee health and conservation; foraging behavior and social organization

(This special issue belongs to the Section Zoology)

Reproduction Under the Microscope: From Oocyte Architecture to Reproductive Function

edited by

Manuel Belli

submission deadline 1 Nov 2026 | Viewed by 24 | Submission Open

Keywords: reproductive biology; oocyte; gametogenesis; fertilization; embryonic development; electron microscopy; ultrastructure; reproductive pathology

Genetics and Evolutionary Biology of Aquatic Organisms

edited by

Qianhong Gu

and Liang Guo

submission deadline 15 Nov 2026 | 4 articles | Viewed by 2220 | Submission Open

Keywords: population genetics; conservation genetics; biodiversity; comparative genomics; polyploidization; rapid adaptation; population genetic divergence; thermal tolerance; hypoxia adaptation; deep-sea pressure adaptation; convergent evolution; molecular clock; phylogeography; population genetic structure; divergence time; inbreeding depression; genetic diversity; genomic selection; genome assembly; transcriptomics; population genomics

(This special issue belongs to the Section Evolutionary Biology)

Erythrocytes in Human Life—Functions Beyond Oxygen Transport

edited by

Vesna Ilic

and

Ivana Drvenica

submission deadline 15 Nov 2026 | Viewed by 184 | Submission Open

Keywords: erythrocytes in physiological processes; erythrocytes in disease pathophysiology; erythrocyte biomechanics; erythrocyte imaging; erythrocyte membrane; erythrocyte metabolism; haemoglobin; immune modulation; redox homeostasis

(This special issue belongs to the Section Cell Biology)

Regulatory Mechanisms of Plant Stress Response

edited by

Yuxuan Hou

and Li Ren

submission deadline 30 Nov 2026 | 3 articles | Viewed by 5805 | Submission Open

Keywords: gene; gene expression; gene function; molecular regulation; genetic resource; phenotype; stress response

(This special issue belongs to the Section Genetics and Genomics)

Physiology and Pathophysiology of the Kidney

edited by Gang Liu

submission deadline 30 Nov 2026 | 3 articles | Viewed by 5264 | Submission Open

Keywords: renal physiology; renal hemodynamics; kidney injury; regenerative therapies; urology

(This special issue belongs to the Section Physiology)

Genetics and Cell Biology in Crop Improvement

edited by

Zhiyong Li

Jian Zhang

, Jie Huang and Xixi Liu

submission deadline 30 Nov 2026 | 1 articles | Viewed by 2647 | Submission Open

Keywords: plant genomics and genetics; gene cloning and function; crop molecular breeding; germplasm enhancement; genetic engineering; plant cell biology; crop adaptability

(This special issue belongs to the Section Plant Science)

The 1st International Online Conference on Biology—“Across Levels of the Biological Organization” (Biology 2025)

edited by

Andrés Moya

submission deadline 30 Nov 2026 | Viewed by 468 | Submission Open

Keywords: biological complexity; climate change; global biodiversity; host-parasite interactions; plant adaptations

Current Research in the Biodiversity, Ecology, and Evolution of Chondrichthyan Fishes (Sharks, Rays and Chimaeras)

edited by

Simon Weigmann

Diego F.B. Vaz

and João Paulo Capretz Batista da Silva

submission deadline 30 Nov 2026 | Viewed by 462 | Submission Open

Keywords: Chondrichthyes; Elasmobranchii; Holocephali; sharks; skates; rays; chimaeras; chimaeras; biodiversity; taxonomy; systematics; ecology; evolution

(This special issue belongs to the Section Marine and Freshwater Biology)

Exploring the Molecular Basis of Cancer: Perspectives from Genetics and Epigenetics

edited by

Shilpa Dhar

submission deadline 30 Nov 2026 | Viewed by 424 | Submission Open

Keywords: cancer genetics; epigenetics; tumor heterogeneity; histone modification; next-generation sequencing (NGS); cancer transcriptomics; gene regulation; mouse model; chromatin remodeling; CHIP-Seq; ATAC-seq; mutation; amplification

(This special issue belongs to the Section Genetics and Genomics)

Breast Cancer: Molecular and Cellular Mechanism and Biomarkers

edited by

Anna Makuch-Kocka

and

Przemysław Kołodziej

submission deadline 30 Nov 2026 | Viewed by 401 | Submission Open

Keywords: breast cancer; biomarkers; molecular mechanisms; multidrug resistance; personalized medicine; molecular targeted therapy; gene expression

(This special issue belongs to the Section Cancer Biology)

Biological Foundations of Psychiatric Disorders

edited by Rammohan Shukla

submission deadline 30 Nov 2026 | Viewed by 273 | Submission Open

Keywords: psychiatric disorders; molecular mechanisms; animal models; therapeutic discovery; genetic associations; sex differences; protocols; methods; behavioral studies; stress-related phenotypes

(This special issue belongs to the Section Neuroscience)

Ecological Dynamics of Vector-Borne Pathogens: From Hosts to Vectors

edited by

Sofia Ferreira Anastácio

Joana Ferrolho Gibson

and Hugo C. R. Vilhena

submission deadline 30 Nov 2026 | Viewed by 114 | Submission Open

Keywords: vector-borne pathogens; host– vector interactions; climate change; disease emergence

(This special issue belongs to the Section Microbiology)

Stem Cell Stress Responses: Mechanisms, Models, and Implications

edited by Taku Kaitsuka

submission deadline 30 Nov 2026 | Viewed by 108 | Submission Open

Keywords: stem cells; stress response; differentiation; heat stress; hypoxic stress; oxidative stress; mechanical stress; proteotoxic stress; membrane protein; stress-inducible transcription factor

(This special issue belongs to the Section Cell Biology)

Neurodegeneration: Pathways and Mechanisms

edited by

Ferdinando Franzoni

and

Giorgia Scarfò

submission deadline 30 Nov 2026 | Viewed by 86 | Submission Open

Keywords: inflammation; oxidative stress; apoptosis; exercise; diet; cellular pathways

(This special issue belongs to the Section Neuroscience)

New Perspectives of Immunity Against SARS-CoV-2

edited by

Jorge A. Soto

and

Felipe Melo-González

submission deadline 30 Nov 2026 | Viewed by 67 | Submission Open

Keywords: innate and adaptive immune responses; viral immune evasion; mucosal and systemic immunity; vaccine-induced protection; host– pathogen interactions; immunomodulation and antiviral strategies

(This special issue belongs to the Section Immunology)

Machine Learning and AI Approaches for Genomic and Transcriptomic Insights in Health and Disease

edited by

Sushil Shakyawar

submission deadline 30 Nov 2026 | Viewed by 35 | Submission Open

Keywords: AI applications in biology and medicine; deep learning approaches in multiomic data integration and analysis; DNA/protein language modeling; computational genomics; AI-driven disease modeling

(This special issue belongs to the Section Bioinformatics)

Insect Habits, Habitats and Interactions

edited by

Leon G. Higley

submission deadline 30 Nov 2026 | Viewed by 31 | Submission Open

Keywords: adaptation; Insecta; plant– insect interactions; life history; niche; coevolution; pollination; disease transmission; insect flight; metamorphosis; sociality

(This special issue belongs to the Section Ecology)

Redox-Active Phytochemicals as Modulators of ROS, RNS and RSS Signaling: From Molecular Mechanisms to Therapeutic Potential

edited by

Lucas Fornari Laurindo

submission deadline 30 Nov 2026 | Viewed by 30 | Submission Open

Keywords: phytochemicals; bioactive compounds; medicinal plants; redox signaling; reactive oxygen species (ROS); reactive nitrogen species (RNS); reactive sulfur species (RSS); antioxidant mechanisms; redox modulation; hormesis; Nrf2 pathway; oxidative stress; natural products; nutraceuticals; health and disease

(This special issue belongs to the Section Plant Science)

Pathophysiology of Chronic Inflammatory Diseases

edited by Vincent Yuan

submission deadline 1 Dec 2026 | 4 articles | Viewed by 7112 | Submission Open

Keywords: chronic inflammation; autoimmune diseases; cytokines; inflammasome; metabolic dysfunction; oxidative stress; biomarkers; epigenetics; personalized medicine; therapeutic targets

(This special issue belongs to the Section Physiology)

Neural and Non-Neural Substrates of Behavior

edited by

Sam Zheng

submission deadline 1 Dec 2026 | Viewed by 37 | Submission Open

Keywords: neural substrate; non-neural substrate; neural network; learning and memory; information processing; behavior

(This special issue belongs to the Section Neuroscience)

Environmental DNA (eDNA) for Assessment of Coastal Marine Biodiversity

edited by

Maurizio Pinna

and

Valeria Specchia

submission deadline 15 Dec 2026 | 2 articles | Viewed by 2826 | Submission Open

Keywords: eDNA metabarcoding; coastal marine ecosystems; biodiversity; genetic distances; ecological indicators

(This special issue belongs to the Section Ecology)

Recent Advances in Understanding Systemic Lupus Erythematosus Pathogenesis

edited by Rohit Upadhyay

submission deadline 15 Dec 2026 | Viewed by 381 | Submission Open

Keywords: systemic lupus erythematosus (SLE); autoimmunity; immune dysregulation; B and T cell biology; interferon signaling; autoantibodies; epigenetics; biomarkers; therapeutic targets; systems immunology

(This special issue belongs to the Section Medical Biology)

Bacterial Secretion Systems: Mechanisms, Regulation, and Their Roles in Microbe–Microbe and Microbe–Host Interactions

edited by

Lingfang Zhu

submission deadline 15 Dec 2026 | Viewed by 100 | Submission Open

Keywords: secretion system; pathogenicity; quorum sensing; expression and regulation; transcriptomics; environmental adaptability; microbial interaction mechanism

(This special issue belongs to the Section Microbiology)

Young Researchers in Marine and Freshwater Biology

edited by

John R. Turner

submission deadline 15 Dec 2026 | Submission Open

Keywords: aquatic ecology; aquatic physiology; aquatic ecosystems; aquatic species adaptation and evolution; aquatic biodiversity; aquatic mammals; aquatic top predators; aquatic invertebrates; aquatic symbioses; aquatic genetics; aquatic microbiology; limnology; biological oceanography; aquatic conservation; protection and sustainable exploitation

(This special issue belongs to the Section Marine and Freshwater Biology)

Biology of Liver Diseases

edited by

Tadashi Namisaki

and

Hiroaki Takaya

submission deadline 20 Dec 2026 | 4 articles | Viewed by 13975 | Submission Open

Keywords: viral hepatitis; alcoholic hepatitis; non-alcoholic steatohepatitis; autoimmune hepatitis; primary biliary cholangitis; liver cirrhosis; liver cancer; portal hypertension

(This special issue belongs to the Section Medical Biology)

Impacts of Climate Change on Terrestrial Carbon Cycling and Biodiversity Across Spatial and Temporal Scales

edited by

Nophea Sasaki

and

Takuji W. Tsusaka

submission deadline 21 Dec 2026 | 4 articles | Viewed by 3567 | Submission Open

Keywords: climate change; terrestrial carbon cycling; biodiversity; spatial and temporal scales; ecosystem resilience; UN CBD; UN Decade on Ecosystem Restoration; responsible business; nature-based solutions; sustainable development

(This special issue belongs to the Section Conservation Biology and Biodiversity)

Advances in Tropical and Subtropical Plant Ecology and Physiology

edited by Naysa Flávia Ferreira Do Nascimento and Edna Ursulino Alves

submission deadline 30 Dec 2026 | 5 articles | Viewed by 2228 | Submission Open

Keywords: tropical plants; plant ecology; plant physiology; environmental adaptations; phenotypic diversity; climate change; biodiversity conservation; sustainable management

(This special issue belongs to the Section Plant Science)

Biology, Pathogenesis, and Genomics of Animal Viruses

edited by Andrea Elizabeth Verna

submission deadline 30 Dec 2026 | Viewed by 53 | Submission Open

Keywords: animal viruses; molecular virology; viral genomics; host– virus interactions; viral pathogenesis; innate immunity; comparative genomics; One Health; emerging viruses

(This special issue belongs to the Section Microbiology)

Advances and Perspectives in tRNA Biology

edited by

Sherif Rashad

submission deadline 30 Dec 2026 | Viewed by 39 | Submission Open

Keywords: tRNA biology; tRNA modifications; sequencing; translational control; codon decoding; tRNA fragments; RNA structure; ribosome dynamics; RNA-based regulation; disease mechanisms

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Neuroprotective Strategies in Preclinical Animal Models of Neurological Disorders

edited by Lucia Buccarello

submission deadline 30 Dec 2026 | Viewed by 34 | Submission Open

Keywords: neuroprotective strategies; intracellular signaling pathways; synaptic dysfunction; oxidative stress: neuronal/cell death; preclinical animal models; neurodegeneration; microglia– neuron interaction; neurotrophin signaling; natural compounds

(This special issue belongs to the Section Neuroscience)

Feature Papers in Immunology

edited by

Natalia Osna

and

Anup Singh Pathania

submission deadline 30 Dec 2026 | Viewed by 31 | Submission Open

Keywords: immune regulation and signaling networks; host– pathogen interactions; innate and adaptive immune responses; immunometabolism and metabolic control of immunity; tumor immunology and immune evasion; autoimmunity and inflammatory diseases; immune modulation and therapeutic targeting; microenvironmental regulation of immune function; molecular and cellular mechanisms of immunity; multi-omics and systems immunology approaches

(This special issue belongs to the Section Immunology)

Advances in Immunomodulation for Inflammatory Diseases

edited by

Seung-Yong Seong

submission deadline 30 Dec 2026 | Viewed by 30 | Submission Open

Keywords: immunomodulation; inflammatory diseases; inflammasome; immune homeostasis; innate immunity; adaptive immunity; signaling pathways; immune regulation; chronic inflammation; autoimmunity; cytokines

(This special issue belongs to the Section Immunology)

Advances in Aquatic Ecological Disasters and Toxicology

edited by

Jinlin Liu

and

Xiangsheng Hong

submission deadline 31 Dec 2026 | 9 articles | Viewed by 8846 | Submission Open

Keywords: aquatic ecological disasters; aquatic toxicology; aquatic ecosystem; algal blooms; pollutants

Biology, Ecology and Management of Aquatic Macrophytes and Algae—2nd Edition

edited by

Jinlin Liu

Wei Liu

and Shuang Zhao

submission deadline 31 Dec 2026 | 5 articles | Viewed by 5916 | Submission Open

Keywords: aquatic macrophytes and algae; ecological planning and management; harmful algal blooms and control; biological resources and environment; aquatic ecosystem stability; ecological restoration; biodiversity; plant physiology; biomarkers; symbiotic microorganisms

The Potential of Genetics and Plant Breeding in Crop Improvement

edited by

Jianyan Zeng

Yuanzhong Jiang

and

Chengjian Xie

submission deadline 31 Dec 2026 | 7 articles | Viewed by 5765 | Submission Open

Keywords: plants; plant signaling pathways; growth and development; genomics; transcriptomics; proteomics; metabolomics; gene transformation; molecular biology; biochemistry; molecular breeding; genome editing; CRISPR/Cas9; marker-assisted selection; genome-wide selection; crop improvement; genetic diversity; quality traits; yield; disease resistance; environmental stress; plant-microbe interactions; drought tolerance; salinity resistance; oxidative stress; phytohormone

(This special issue belongs to the Section Plant Science)

Radiation and Biology: Investigating Cellular, Organismal, and Environmental Responses

edited by

Narongchai Autsavapromporn

Bing Wang

Takanori Katsube

and

Jiraporn Kantapan

submission deadline 31 Dec 2026 | 3 articles | Viewed by 5600 | Submission Open

Keywords: radiation-induced DNA damage and repair pathways; oxidative stress and redox signaling in radiation response; radiation-induced epigenetic modifications; radiation-induced immunomodulation and inflammation; radiation-induced carcinogenesis and disease susceptibility; ecological consequences of ionizing radiation

(This special issue belongs to the Section Medical Biology)

Young Researchers in Plant Sciences

edited by

Luigi De Bellis

submission deadline 31 Dec 2026 | 3 articles | Viewed by 4950 | Submission Open

Keywords: biodiversity; biogeography; biotic and abiotic stress responses; carbon sequestration; ecosystem functions; gene– function relationships; photosynthesis; phytohormones; phytoremediation; plant interactions with viruses; bacteria; fungi; plants; and animals; primary and secondary metabolism; seed development; signalling pathways; structure– function simulation modelling

(This special issue belongs to the Section Plant Science)

Sustainable Management of Aquatic Animal Health: Advances in Immunology, Pathogenesis, and Innovative Disease Control Strategies

edited by

Baofeng Su

and

Dongdong Zhang

submission deadline 31 Dec 2026 | 2 articles | Viewed by 3663 | Submission Open

Keywords: aquatic animal health; immunology; pathogenesis; CRISPR-based innovations; sustainable aquaculture

(This special issue belongs to the Section Immunology)

Responses and Resistance Mechanisms of Plants Under Environmental Stress

edited by

Aoxue Wang

submission deadline 31 Dec 2026 | 4 articles | Viewed by 3656 | Submission Open

Keywords: disease resistance; cold tolerance; defense priming; pathogen perception

(This special issue belongs to the Section Plant Science)

Advances in Biological Research into Shrimps, Crabs and Lobsters (2nd Edition)

edited by Lutz Auerswald

submission deadline 31 Dec 2026 | 4 articles | Viewed by 1102 | Submission Open

Keywords: Crustacea; Decapoda; biology; fishery; aquaculture; ecology; bio-compounds; seafood; physiology; immunology; genetics

(This special issue belongs to the Section Zoology)

Pathobiology of Cardiac Arrhythmias and Heart Failure Issues

edited by Mohit Hulsurkar

submission deadline 31 Dec 2026 | 1 articles | Viewed by 942 | Submission Open

Keywords: cardiac arrhythmias; atrial fibrillation; heart failure; ion channelopathy; cardiac fibrosis; cardiomyopathy

(This special issue belongs to the Section Physiology)

Aquatic Economic Animal Breeding and Healthy Farming (2nd Edition)

edited by Yude Wang and Shengwei Luo

submission deadline 31 Dec 2026 | 1 articles | Viewed by 666 | Submission Open

Keywords: rice– fish; fish; and aquaculture; hybridization and genetic breeding; nutrient additive and requirement; physiology and immune response; disease control; pathogenesis research; probiotic identification and function; transcriptomics; proteomics; metabonomics

(This special issue belongs to the Section Zoology)

Feature Papers on Toxicology

edited by

Hui Xu

submission deadline 31 Dec 2026 | 2 articles | Viewed by 611 | Submission Open

Keywords: toxicology; cellular toxicity; organ toxicity; biomarkers; molecular mechanisms; in vitro models; in vivo models; risk assessment; environmental exposures; chemical toxicology

(This special issue belongs to the Section Toxicology)

Cellular Senescence in Development, Regeneration, Aging, and Cancer

edited by

Selim Chaib

submission deadline 31 Dec 2026 | 1 articles | Viewed by 596 | Submission Open

Keywords: cellular senescence; aging; cancer; obesity; metabolism; geroscience; age-related diseases; SASP; senolytics; biomarkers

Vegetation Detection and Ecosystem Carbon Modeling

edited by

Teerawong Laosuwan

and

Yannawut Uttaruk

submission deadline 31 Dec 2026 | Viewed by 461 | Submission Open

Keywords: vegetation detection; ecosystem carbon modeling ; biomass estimation ; carbon dynamics ; forest and agro-ecosystem monitoring ; remote sensing ; allometric modeling ; machine learning ; UAV imagery; climate-change mitigation

(This special issue belongs to the Section Ecology)

Displaying special issue 301-350 on page 7 of 8.

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