Special Issues

Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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The Regulation of Glucose Homeostasis
edited by Aaron Aykut Uner
submission deadline 31 Aug 2025 | Viewed by 199 | Submission Open
Keywords: glucose homeostasis; brain; type 1 diabetes; type 2 diabetes; insulin sensitivity; beta-cell regeneration
(This special issue belongs to the Section Physiology)
Biological Advances in Pluripotent Stem Cells
edited by and Matthias Jung
submission deadline 31 Aug 2025 | Viewed by 173 | Submission Open
Keywords: induced pluripotent stem cell; embryonic stem cell; regenerative medicine; drug research; organoid; translational biology
(This special issue belongs to the Section Cell Biology)
Biosynthesis of Metabolites from Microorganisms, or Microorganism-Host Interaction? (Volume II) submission deadline 1 Sep 2025 | 5 articles | Viewed by 12561 | Submission Open
Keywords: biosynthesis; biological activity; biosynthesis regulation; microbial metabolites; microbe– host reaction
(This special issue belongs to the Section Microbiology)
Viral Infections in Animals: Pathogenesis and Immunity
edited by
submission deadline 1 Sep 2025 | 1 articles | Viewed by 358 | Submission Open
Keywords: virus– host interactions; antiviral immunity; mechanisms of viral pathogenesis
(This special issue belongs to the Section Immunology)
Feature Review Papers on Developmental Biology
edited by
submission deadline 15 Sep 2025 | 6 articles | Viewed by 12552 | Submission Open
Keywords: embryo/fetus development; differentiation; growth; homeostasis; regeneration; aging; cell cycle regulation; stem cells; organoids
(This special issue belongs to the Section Developmental and Reproductive Biology)
Biological Rhythms and Molecular Clockworks in Physiology and Pathology submission deadline 30 Sep 2025 | 10 articles | Viewed by 28638 | Submission Open
Keywords: biological rhythms; molecular clockworks; circadian timing system; circadian desynchrony; circadian disruption; chronopathology; chronopharmacology and chronotherapeutics; chronomedicine
(This special issue belongs to the Section Physiology)
Artificial Intelligence Research for Complex Biological Systems submission deadline 30 Sep 2025 | 6 articles | Viewed by 5382 | Submission Open
Keywords: deep learning; generative artificial intelligence; bioinformatics; complex biological systems; cancer; neuroscience; next-generation sequencing; single-cell and bulk omics; genomics
(This special issue belongs to the Section Bioinformatics)
Plant Breeding: From Biology to Biotechnology
edited by Juwu Gong
submission deadline 30 Sep 2025 | 5 articles | Viewed by 5232 | Submission Open
Keywords: plant breeding; biotechnology; molecular marker-assisted selection; genetic engineering; genome editing; tissue culture; phenotype; genetics; omics
(This special issue belongs to the Section Biotechnology)
Molecular Basis of Bone Homeostasis and Skeletal Diseases
edited by
submission deadline 30 Sep 2025 | 3 articles | Viewed by 4302 | Submission Open
Keywords: osteoclast; osteoblast; bone; skeletal disease; bone formation; bone resorption; osteoporosis; osteopetrosis; human genetics; mouse genetics
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Research Advancements in Oral Biology
edited by and Nina Petrović
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1559 | Submission Open
Keywords: oral biology; oral tissue regeneration; artificial intelligence (AI) in dentistry; genomics and proteomics in dentistry; dental research; salivary diagnostics
(This special issue belongs to the Section Medical Biology)
Research Progress on Melanocytes and Melanin
edited by Zeina Tannous
submission deadline 30 Sep 2025 | Viewed by 352 | Submission Open
Keywords: melanin; melanocytes; melanocyte stem cell; pigmentation; melanoma; dysplastic nevi; vitiligo; melasma
(This special issue belongs to the Section Medical Biology)
Molecular Mechanisms of Cell Signal Transduction
edited by Wenjing Zhang
submission deadline 30 Sep 2025 | Viewed by 230 | Submission Open
Keywords: molecular interactions in signaling; phosphorylation and signal propagation; post-translational modifications; cross-talk between signaling pathways; cellular response to extracellular stimuli; metabolic regulation and signaling; signaling in cancer progression; inflammatory signaling pathways; role of signaling in stem cell differentiation; innovative imaging techniques for signaling
(This special issue belongs to the Section Cell Biology)
The Role of Innate Immunity in Organ Transplantation
edited by Todd V. Brennan
submission deadline 30 Sep 2025 | Viewed by 222 | Submission Open
Keywords: innate immunity; allograft rejection; transplantation; immune tolerance
(This special issue belongs to the Section Medical Biology)
Island Ecology and Biodiversity: Managing the Effects of Climate and Land-Use Change
edited by Kealohanuiopuna Mark Kinney and Susan Cordell
submission deadline 30 Sep 2025 | Viewed by 217 | Submission Open
Keywords: island biogeography; biodiversity conservation; invasive species management; biocultural approaches; ecosystem resilience; landscape ecology; environmental sustainability; climate adaptation; social– ecological systems; restoration ecology       TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in English   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com
(This special issue belongs to the Section Ecology)
Physiology and Ecology of Animal Parasites and Related Diseases
edited by Marcela K. Castelo
submission deadline 30 Sep 2025 | Viewed by 206 | Submission Open
Keywords: parasites; parasitoids; physiology; ecology; ecophysiology; diseases; global change
(This special issue belongs to the Section Zoology)
Metabolic Interactions between the Gut Microbiome and Host
edited by and
submission deadline 30 Oct 2025 | 5 articles | Viewed by 9157 | Submission Open
Keywords: gut microbiome; host; metabolome; microbial heterogeneity; biomolecules
(This special issue belongs to the Section Microbiology)
Multi-omics Approaches in Agricultural Crops to Unravel Responses to Environmental Stresses and Advance Sustainable Agriculture
edited by
submission deadline 30 Oct 2025 | 2 articles | Viewed by 2266 | Submission Open
Keywords: plant functional genomics; environmental stress; climate change; crop yield; crop quality; nutritional properties; omics approaches; genomics; transcriptomics; proteomics; metabolomics; epigenomics; phenomics; stress-tolerant crops; breeding strategies; data integration; systems biology; sustainable agriculture; underutilized crops; orphan crops; beneficial microorganisms
(This special issue belongs to the Section Plant Science)
Pathophysiology of Hearing Loss
edited by Charles E. Bishop
submission deadline 30 Oct 2025 | Viewed by 202 | Submission Open
Keywords: hearing loss; cochlea; noise; deafness genes; cell death; hair cells; inner ear; biotoxicity; metabolic risk; gene mutation; physiology and pathophysiology; animal models; biomarkers and molecular mechanisms
(This special issue belongs to the Section Physiology)
Advances in the Fields of Neurotrauma and Neuroregeneration submission deadline 31 Oct 2025 | 8 articles | Viewed by 39469 | Submission Open
Keywords: neurotrauma; spinal cord injury; traumatic brain injury; neuropathic pain; neuroinflammation; axonal regeneration; postinjury plasticity; neurorehabilitation; cell transplantation
(This special issue belongs to the Section Neuroscience)
Young Researchers in Neuroscience
edited by Yansheng Du
submission deadline 31 Oct 2025 | 2 articles | Viewed by 13908 | Submission Open
Keywords: neurobiology; cell biology; molecular mechanisms; neural development; synaptic function; ion channels; neurotransmitter systems; gene expression; neuronal signaling; cellular physiology
(This special issue belongs to the Section Neuroscience)
Immunosenescence and Its Modification by Interventions
edited by and Luca Pangrazzi
submission deadline 31 Oct 2025 | 1 articles | Viewed by 3789 | Submission Open
Keywords: immunosenescence; aging immune system; inflammaging; vaccine efficacy in elderly; nutritional immunomodulation; exercise and immunity; senolytic therapies; T-cell exhaustion; thymic rejuvenation; age-related diseases
(This special issue belongs to the Section Immunology)
Pathogen-Host Interaction and Vaccine/Drug Design
edited by Iga Kucharska
submission deadline 31 Oct 2025 | 1 articles | Viewed by 2272 | Submission Open
Keywords: infectious diseases; host– pathogen interactions; vaccine; drug design; immune evasion; immunogen
(This special issue belongs to the Section Medical Biology)
Progress in Wildlife Conservation, Management and Biological Research
edited by Ana Carolina Srbek-Araujo
submission deadline 31 Oct 2025 | 3 articles | Viewed by 2233 | Submission Open
Keywords: adaptive capacity; climate change; conservation opportunities; species vulnerability; threatened species; wildlife conservation; wildlife management
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Advances in Omics Approaches for Understanding Metabolic Disorders: Environmental and Nutritional Perspectives
edited by Yue Ge
submission deadline 31 Oct 2025 | 1 articles | Viewed by 935 | Submission Open
Keywords: metabolic disorders; environmental exposures; nutritional factors; omics technologies; co-exposures; cumulative toxicity; metabolic pathways; human health risk assessment; advanced in vitro models; systems toxicology
(This special issue belongs to the Section Physiology)
Advancing Crop Nutritional Quality Through Genomic Approaches
edited by Gen Xu
submission deadline 31 Oct 2025 | 1 articles | Viewed by 465 | Submission Open
Keywords: crop improvement; genomics; multi-omics; genetic loci; breeding
(This special issue belongs to the Section Plant Science)
Extracellular Vesicles: Biogenesis and Functions in the Complex Landscape of Differentiation and Disease
edited by
submission deadline 31 Oct 2025 | Viewed by 432 | Submission Open
Keywords: stem cell biology; stem cell differentiation; adipogenesis; neurogenesis; extracellular vesicles in stem cell differentiation; ncRNAs; tumor microenvironment; intercellular communication
(This special issue belongs to the Section Cell Biology)
Plant-Microbe Interaction: The Cellular Mechanism Influence Plant Health
edited by and Gongjun Shi
submission deadline 31 Oct 2025 | Viewed by 335 | Submission Open
Keywords: plant-microbe interaction; plant health; plant immunity; gene-for-gene model; resistosomes; metabolic crosstalk; climate change
Transcriptional Regulation in Eukaryotes
edited by Anil Kumar Panigrahi
submission deadline 31 Oct 2025 | Viewed by 318 | Submission Open
Keywords: transcription factors (TFs); transcriptional coregulators; RNA polymerase II; chromatin modifications and remodeling; enhancers; silencers; non-coding RNAs; 3D chromatin architecture; multi-omics integration; single-cell technologies
(This special issue belongs to the Section Genetics and Genomics)
Mechanisms of Drug Resistance in Cancer Cells
edited by , and
submission deadline 31 Oct 2025 | Viewed by 268 | Submission Open
Keywords: drug resistance; mechanisms; cell growth; cell proliferation; efficacy
(This special issue belongs to the Section Medical Biology)
Advancing Molecular Mechanisms and Therapeutic Innovations in Neurodegenerative Diseases
edited by Tao Yang
submission deadline 31 Oct 2025 | Viewed by 162 | Submission Open
Keywords: neurodegenerative diseases; Alzheimer's disease; amyotrophic lateral sclerosis; Parkinson's disease; Huntington's disease; frontotemporal dementia; small molecules; synaptic dysfunction; neuroinflammation; biomarkers
(This special issue belongs to the Section Neuroscience)
DNA Repair and DNA Damage Response (DDR) in Oncology
edited by
submission deadline 31 Oct 2025 | Viewed by 135 | Submission Open
Keywords: DNA repair and DNA damage response pathways; cancer target therapy; DNA replication stress response in genome stability; oxidative stress response and redox regulation; DNA single-strand break repair and signaling
(This special issue belongs to the Section Cancer Biology)
Mitochondria and Cardiovascular Diseases
edited by Qingxun Hu
submission deadline 31 Oct 2025 | Viewed by 125 | Submission Open
Keywords: cardiovascular diseases; mitochondria; pathophysiology; cardiology; cell metabolism; animal models; epigenetics; redox biology
(This special issue belongs to the Section Physiology)
2nd Edition: Conservation and Evolution of Wildlife in the Context of Climate Change and Human Population Growth
edited by
submission deadline 1 Nov 2025 | 1 articles | Viewed by 694 | Submission Open
Keywords: changes; local temperature; adaptation; evolution; animals; plants
(This special issue belongs to the Section Behavioural Biology)
Lysosomes and Diseases Associated with Its Dysfunction submission deadline 15 Nov 2025 | 4 articles | Viewed by 17216 | Submission Open
Keywords: activities; mutations; endocytosis; autophagy; metabolism; proteins
(This special issue belongs to the Section Cell Biology)
Biological Nitrogen Removal in the Multi-Omics Era: Coupling Anammox with Microbial-Mineral Synergy
edited by Zhaoming Zheng, and
submission deadline 25 Nov 2025 | Viewed by 106 | Submission Open
Keywords: sustainable nitrogen removal processes; anaerobic ammonium oxidation; aerobic granular sludge; microbial– mineral interactions; multi-omics microbial analysis; bioengineering in wastewater treatment; nitrogen biogeo-chemical cycle; detection and removal of emerging pollutants; water quality assurance technologies; resource re-covery from wastewater
(This special issue belongs to the Section Microbiology)
Physiology and Pathophysiology of the Kidney
edited by Gang Liu
submission deadline 30 Nov 2025 | 2 articles | Viewed by 2977 | Submission Open
Keywords: renal physiology; renal hemodynamics; kidney injury; regenerative therapies; urology
(This special issue belongs to the Section Physiology)
Germ, Sertoli and Leydig Cells in the Testis
edited by and María Fernanda Riera
submission deadline 30 Nov 2025 | 1 articles | Viewed by 2673 | Submission Open
Keywords: Sertoli cells; Leydig cells; spermatogonia; spermatocytes; spermatozoa; stem cell niche; testis; omics analysis; environmental toxicants; non-coding RNAs  
(This special issue belongs to the Section Cell Biology)
Regulatory Mechanisms of Plant Stress Response
edited by and Li Ren
submission deadline 30 Nov 2025 | 3 articles | Viewed by 2103 | Submission Open
Keywords: gene; gene expression; gene function; molecular regulation; genetic resource; phenotype; stress response
(This special issue belongs to the Section Genetics and Genomics)
Genetics and Cell Biology in Crop Improvement
edited by , , Jie Huang and Xixi Liu
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1572 | Submission Open
Keywords: plant genomics and genetics; gene cloning and function; crop molecular breeding; germplasm enhancement; genetic engineering; plant cell biology; crop adaptability
(This special issue belongs to the Section Plant Science)
Unraveling the Tumor-Immune Microenvironment Using Transcriptomics submission deadline 30 Nov 2025 | 2 articles | Viewed by 1477 | Submission Open
Keywords: tumor-immune microenvironment; immune cells; tumor cells; stromal cells; signaling molecules; extracellular matrix (ECM); vascular network
(This special issue belongs to the Section Cancer Biology)
Mitochondrial Dysfunction and Aging
edited by Huiliang Zhang
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1377 | Submission Open
Keywords: mitochondrial dysfunction; aging; cardiovascular diseases; Alzheimer’ s disease and related dementia; stem cell; skeletal muscle; kidney
(This special issue belongs to the Section Medical Biology)
Advances in Redox Metabolism and Cellular Homeostasis submission deadline 30 Nov 2025 | 1 articles | Viewed by 1053 | Submission Open
Keywords: oxidative stress; peroxiredoxins; hydrogen peroxide; redox regulation; thiol modification; reactive oxygen species; iron sulfur clusters; redox signaling
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Diet and Environmental Stress Impacts on Farm Animal Production
edited by and Michael Chimonyo
submission deadline 30 Nov 2025 | Viewed by 753 | Submission Open
Keywords: animal production; feed types; feed preparation; feed additives; diet quality and palatability; climate variability; housing environment
(This special issue belongs to the Section Zoology)
Managing Hybridizing Populations: Threats or Opportunities for Conservation?
edited by and Marco Musiani
submission deadline 30 Nov 2025 | Viewed by 632 | Submission Open
Keywords: natural hybridization; anthropogenic hybridization; adaptive introgression; hybrid fitness; coexistence of wildlife and free-ranging domestic animals; management of hybridizing populations
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Exposure to Heavy Metals: Advances in Cytotoxicity and Genotoxicity
edited by Qianru Chi and Yi Zhao
submission deadline 30 Nov 2025 | Viewed by 395 | Submission Open
Keywords: heavy metal pollutants; exposure assessment; toxic mechanism; biomarkers; metabolomics; environmental quality monitoring; bioinformatics analysis methods
(This special issue belongs to the Section Toxicology)
Heavy Metal Pollution and Bioremediation: Application and Mechanism
edited by , Ruiyu Lin and Rongfei Wei
submission deadline 30 Nov 2025 | Viewed by 283 | Submission Open
Keywords: heavy metal pollutants; microbial remediation; phytoremediation; animal remediation; plant– soil– microbe interactions; enhanced remediation; combined remediation; hyperaccumulator plants; microbial-induced calcium carbonate precipitation
(This special issue belongs to the Section Toxicology)
Current Research in the Biodiversity, Ecology, and Evolution of Chondrichthyan Fishes (Sharks, Rays and Chimaeras)
edited by , and João Paulo Capretz Batista da Silva
submission deadline 30 Nov 2025 | Viewed by 280 | Submission Open
Keywords: Chondrichthyes; Elasmobranchii; Holocephali; sharks; skates; rays; chimaeras; chimaeras; biodiversity; taxonomy; systematics; ecology; evolution
(This special issue belongs to the Section Marine Biology)
Breast Cancer: Molecular and Cellular Mechanism and Biomarkers submission deadline 30 Nov 2025 | Viewed by 252 | Submission Open
Keywords: breast cancer; biomarkers; molecular mechanisms; multidrug resistance; personalized medicine; molecular targeted therapy; gene expression
(This special issue belongs to the Section Cancer Biology)
Exploring the Molecular Basis of Cancer: Perspectives from Genetics and Epigenetics
edited by
submission deadline 30 Nov 2025 | Viewed by 246 | Submission Open
Keywords: cancer genetics; epigenetics; tumor heterogeneity; histone modification; next-generation sequencing (NGS); cancer transcriptomics; gene regulation; mouse model; chromatin remodeling; CHIP-Seq; ATAC-seq; mutation; amplification
(This special issue belongs to the Section Genetics and Genomics)
Biological Foundations of Psychiatric Disorders
edited by Rammohan Shukla
submission deadline 30 Nov 2025 | Viewed by 189 | Submission Open
Keywords: psychiatric disorders; molecular mechanisms; animal models; therapeutic discovery; genetic associations; sex differences; protocols; methods; behavioral studies; stress-related phenotypes
(This special issue belongs to the Section Neuroscience)
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