Sexual Determination and Reproductive Regulation in Aquatic Organisms

A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Developmental and Reproductive Biology".

Deadline for manuscript submissions: 31 January 2026 | Viewed by 502

Special Issue Editor


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Guest Editor
College of Life Sciences, Hunan Normal University, Changsha 410081, China
Interests: sex determining; sex chromosome; sex-determining gene; turnover of sex-determining gene or sex chromosome
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Sexual determination and reproductive regulation in aquatic organisms, particularly fish species, encompass a diverse array of mechanisms that govern sexual differentiation and reproduction. These processes are pivotal for the survival, growth, and evolution of populations. Gender in fish can be influenced by a complex interplay of genetic, hormonal, and environmental factors, resulting in a spectrum of reproductive strategies ranging from gonochorism to hermaphroditism. Understanding these mechanisms holds significant implications for conservation biology, aquaculture, and fishery management, as they can inform strategies to protect fish populations, enhance productivity, and ensure sustainability.

Recent advancements in technology have significantly accelerated research into sexual determination in aquatic organisms. High-throughput sequencing technologies, such as next-generation sequencing (NGS) and third-generation sequencing (TGS), have transformed the field by enabling researchers to swiftly and accurately identify and analyze the genetic components involved in sex determination. These technologies have facilitated the discovery of sex-linked genes, sex chromosomes, and sex-determining regions in various fish genomes. Furthermore, genome editing techniques like CRISPR/Cas9 have provided unprecedented precision in manipulating genes and studying their roles in sexual differentiation. These technological advancements have deepened our understanding of the genetic architecture underlying sex determination and opened new avenues for exploring the interactions between genetic and environmental factors in shaping sexual fate.

This Special Issue solicits original research articles and comprehensive reviews focusing on sexual determination and reproductive regulation in aquatic organisms. Submissions should emphasize the influence of genetic factors (such as sex chromosomes and key regulatory genes) and environmental factors (including temperature and pollutants) on sexual differentiation, the evolution of sex-determining mechanisms, and their practical applications in breeding programs. Areas of interest encompass sex determination pathways, the evolution of sex chromosomes, the epigenetic regulation of sexual development, and innovative gender control methodologies in aquaculture.

Best regards,

Dr. Liang Guo
Guest Editor

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Keywords

  • sex-determining gene
  • sex chromosome
  • sex control breeding
  • sex-determining pathway

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Published Papers (1 paper)

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Research

17 pages, 6248 KB  
Article
Functional Spermatogenesis Across Testicular Developmental Stages in Neomale Large Yellow Croaker (Larimichthys crocea) Revealed by Histology and Gonadal Specific Cellular Markers
by Xu Liu, Weihua Hu, Ruiyi Chen, Yang Yang, Sixian Yang and Dongdong Xu
Biology 2025, 14(8), 1054; https://doi.org/10.3390/biology14081054 - 14 Aug 2025
Viewed by 336
Abstract
Gonadal development and spermatogenesis critically influence fish reproductive performance. Neomales (genetically female but functionally male) are indispensable for generating all-female populations, yet their spermatogenesis remains understudied. In the present study, we systematically investigated gonadal maturation in neomales of the large yellow croaker ( [...] Read more.
Gonadal development and spermatogenesis critically influence fish reproductive performance. Neomales (genetically female but functionally male) are indispensable for generating all-female populations, yet their spermatogenesis remains understudied. In the present study, we systematically investigated gonadal maturation in neomales of the large yellow croaker (Larimichthys crocea), an economically important marine species exhibiting sexually dimorphic growth. We examined the growth performance and gonadal development throughout the maturation process in neomales and control males. Results showed comparable growth performance but a temporal divergence in gonadal development: the gonadosomatic index (GSI) of neomales was significantly higher than control males at 400 and 430 days post-hatching (dph), but not at 460 dph during the reproductive period. Histological, ultrastructural (TEM), and immunofluorescence analyses collectively demonstrated that neomale testes contained all major spermatogenic cell types. Their morphological characteristics and expression patterns of key markers—germ cells (vasa), Sertoli cells (sox9a), and meiotic recombination (dmc1)—were similar to control males. These findings enhance understanding of gonadal development and spermatogenesis in neomales, providing a theoretical and technical foundation for large-scale production of all-female large yellow croaker. Full article
(This article belongs to the Special Issue Sexual Determination and Reproductive Regulation in Aquatic Organisms)
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