Large Animal Experimental and Epidemiological Models for Diseases

Dear Colleagues,

Animal models play a crucial role in the study of both infectious and non-infectious diseases, enabling researchers to replicate disease processes and test interventions in a controlled environment. Large experimental animal models, such as dogs, pigs, sheep, and non-human primates, are increasingly used in biomedical research because they bridge the gap between small animal models and humans. They offer better anatomical and physiological similarities to humans, particularly for non-infectious diseases such as cardiovascular, metabolic, reproductive, genetic, and neurodegenerative conditions. These models facilitate more accurate and relevant testing of new therapies and treatments, supporting long-term studies and clinical dosing regimens. In public health and livestock management, large animal epidemiological models represent disease transmission dynamics among animals and humans. They help in evaluating control measures and predicting outcomes in infectious and zoonotic diseases, as well as antibiotic resistance. Livestock serve as valuable models in studying human diseases, enabling research on disease dynamics, treatment testing, and vaccine development.

This Special Issue will showcase reviews and original research articles that provide up-to-date information and future perspectives on large animal experimental and epidemiological models of diseases, with possible topics including (but not limited to) prevention, pathobiology, diagnosis, prediction, treatment, outbreaks, and control.

We look forward to receiving your contributions.

Prof. Dr. Witaya Suriyasathaporn
Dr. Sho Nakamura
Guest Editors

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