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Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Vector-Borne Diseases: Host Infection Mechanisms, Immune Response and Epidemiology

edited by

Sahatchai Tangtrongsup

and

Nattawooti Sthitmatee

submission deadline 30 Jun 2026 | Viewed by 1217 | Submission Open

Keywords: vector-borne pathogens; host– vector– pathogen interactions; immune response to arthropod-borne infections; vector competence and ecology; one health surveillance; emerging zoonoses; tick-borne diseases; animal vector-borne diseases; veterinary public health

(This special issue belongs to the Section Immunology)

Genomics and Bioinformatics in Microorganism from the Class Insecta

edited by Irám Pablo Rodríguez-Sánchez

submission deadline 30 Jun 2026 | 1 articles | Viewed by 998 | Submission Open

Keywords: genomics; bioinformatics; microbial communities; insect microbiomes; multi-omics; metagenomics; transcriptomics; host-microbe interactions; evolutionary dynamics; biotechnological applications

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Paper Collection: Understanding Immune Systems

edited by

Sigrun Lange

and Jameel M. Inal

submission deadline 30 Jun 2026 | 1 articles | Viewed by 983 | Submission Open

Keywords: immune mechanisms; evolutionary immunology; comparative immunology; innate immunity; adaptive immunity; autoimmunity; chronic inflammation; immune ageing; host– pathogen interactions; vaccinology; regenerative medicine

(This special issue belongs to the Section Immunology)

The Plasticity of Autonomic Ganglia

edited by

Miguel Angel Morales

submission deadline 30 Jun 2026 | 1 articles | Viewed by 977 | Submission Open

Keywords: acetylcholine; GABA; co-transmission; neuroplasticity; transmitter segregation; synapse; gLTP; binge-eating disorders; dysautonomia; heart disease

(This special issue belongs to the Section Neuroscience)

Precision Nutrition: Unraveling the Molecular Physiology of Nutrient–Gut–Health Axis in Livestock and Poultry

edited by Shengchen Wang, Tingting Li and Xiaoyan Cui

submission deadline 30 Jun 2026 | 1 articles | Viewed by 871 | Submission Open

Keywords: livestock; poultry; animal production; essential nutrients; bioactive compounds; metabolism; animal health; gut physiology; microbiota; molecular

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Biology, Ecology and Management of Invasive Alien Plants (2nd Edition)

edited by

Guoqi Chen

and

Jiang Wang

submission deadline 30 Jun 2026 | 1 articles | Viewed by 769 | Submission Open

Keywords: changes in the composition and distribution of alien plants; invasive mechanisms; invasiveness; invasibility; invasive population; invasive plant interactions with other organisms; impacts on environment; ecosystem services and human health; chemical control; management of invasive plants; utilization of invasive plants

(This special issue belongs to the Section Plant Science)

Advancing Crop Nutritional Quality Through Genomic Approaches

edited by Gen Xu

submission deadline 30 Jun 2026 | 1 articles | Viewed by 762 | Submission Open

Keywords: crop improvement; genomics; multi-omics; genetic loci; breeding

(This special issue belongs to the Section Plant Science)

Extracellular Vesicles: Biogenesis and Functions in the Complex Landscape of Differentiation and Disease

edited by

Sorina Dinescu

submission deadline 30 Jun 2026 | Viewed by 536 | Submission Open

Keywords: stem cell biology; stem cell differentiation; adipogenesis; neurogenesis; extracellular vesicles in stem cell differentiation; ncRNAs; tumor microenvironment; intercellular communication

(This special issue belongs to the Section Cell Biology)

Interactions Between Membrane Proteins and Membrane Lipids

edited by

Youzhong Guo

submission deadline 30 Jun 2026 | Viewed by 461 | Submission Open

Keywords: membrane protein; lipid bilayer; enzyme; channel; receptor; transporter; cryo-EM; X-ray crystallography; structural biology; drug target

(This special issue belongs to the Section Biophysics)

Mechanisms of Drug Resistance in Cancer Cells

edited by

Xin Chen

Tuoen Liu

and

Wei Lei

submission deadline 30 Jun 2026 | Viewed by 365 | Submission Open

Keywords: drug resistance; mechanisms; cell growth; cell proliferation; efficacy

(This special issue belongs to the Section Medical Biology)

Applications of Yeast Biotechnology

edited by

Pornthap Thanonkeo

submission deadline 30 Jun 2026 | Viewed by 185 | Submission Open

Keywords: biofuel and feed production; biological control; waste treatment and utilization; yeast metabolites; enzyme technology; yeast strain development; process development

(This special issue belongs to the Section Biotechnology)

Nutritional Physiology of Animals

edited by

Bai Xue

Yuhong Gao

and Jia Zhou

submission deadline 30 Jun 2026 | Viewed by 177 | Submission Open

Keywords: animals; nutrition; feed additives; novel feed resources; physiology; digestibility; metabolism; stress; reproduction; multi-omics

(This special issue belongs to the Section Physiology)

Genetic Breeding and Reproduction of Aquatic Animals—2nd Edition

edited by

Huaping Zhu

, Dongmei Ma and

Zaixuan Zhong

submission deadline 30 Jun 2026 | Viewed by 137 | Submission Open

Keywords: genetic breeding; reproduction technology; gene; protein; molecular marker; trait; QTLs; molecular marker; fish; shrimp; crab; shellfish; aquatic animals; transcriptomics; proteomics; metabonomics

(This special issue belongs to the Section Zoology)

Breaking Barriers in Metabolic Health: Novel Insights into Obesity and Metabolic Disorders

edited by Aijun Qiao

submission deadline 30 Jun 2026 | Viewed by 119 | Submission Open

Keywords: metabolic disorders; pathogenesis and mechanisms; biomarkers

(This special issue belongs to the Section Medical Biology)

Environmental and Disease-Driven Biomechanical Stress in Red Blood Cell Biology

edited by

Marijke Grau

submission deadline 30 Jun 2026 | Viewed by 109 | Submission Open

Keywords: RBCs and environmental factors; RBCs and biomechanical stress; RBCs and pathological conditions; RBCs and microcirculation; RBCs and biomarkers for diseases

(This special issue belongs to the Section Biophysics)

Cytochrome P450s Across Biological Systems: From Molecular Mechanisms to Biotechnological and Biomedical Applications

edited by

Pradeepraj Durairaj

submission deadline 30 Jun 2026 | Viewed by 95 | Submission Open

Keywords: cytochrome P450 (CYP450); drug metabolism; xenobiotic metabolism; biocatalysis and biotransformation; orphan enzymes; redox biology; structural biology; synthetic biology; enzyme engineering; multi-omics approaches

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Novel Insights of Bone Repair: Strategies for Improvement, Microscopic, Molecular and Ultrastrastructural Aspects—2nd Edition

edited by

Roberta Okamoto

submission deadline 30 Jun 2026 | Viewed by 92 | Submission Open

Keywords: bone repair; aging; bone remodeling; biomaterials; drug delivery; bone regeneration

(This special issue belongs to the Section Medical Biology)

Biosynthesis and Regulation of Plant Tissue-Specific Metabolites

edited by

Xiumin Fu

submission deadline 30 Jun 2026 | Viewed by 81 | Submission Open

Keywords: underground tissue metabolites; root; root exudates; genetic regulation; rhizosphere microbial interaction; environmental response

(This special issue belongs to the Section Plant Science)

Immune Response Regulation in Animals (2nd Edition)

edited by

Rong Gao

and

Hua-Ji Qiu

submission deadline 30 Jun 2026 | Viewed by 80 | Submission Open

Keywords: immunoregulation of animals; vaccination; immunomodulators; immune memory; cytokine; biotechnology; immune response; molecular networks

(This special issue belongs to the Section Immunology)

The Role of Epigenetics in Cell Fate Determination, Cancer Development, and Aging

edited by

Yong Tao

and

Wenbing Xie

submission deadline 30 Jun 2026 | Viewed by 59 | Submission Open

Keywords: epigenetics; cell fate determination; cell fate determination; cancer epigenetics; aging; DNA methylation; histone modification; chromatin remodeling; epigenome editing; epigenetic therapy; stem cells

(This special issue belongs to the Section Cell Biology)

One Health Insights: From Molecules to Ecosystems

edited by Leonardo Oliveira Reis and Lucas Assoni

submission deadline 30 Jun 2026 | Viewed by 57 | Submission Open

Keywords: One Health; environmental health; planetary health; cancer epidemiology; comparative oncology; emerging diseases; immuno-oncology; molecular mechanisms

Neurogenetics of Behaviour (Volume II)

edited by

Charalambos Kyriacou

submission deadline 30 Jun 2026 | Viewed by 35 | Submission Open

Keywords: behaviour; genetics; molecules; species; brain; networks; health; disease

(This special issue belongs to the Section Genetics and Genomics)

Research on the Interaction Mechanism Between Animal Intestine and Its Microbiota

edited by

Zongjie Li

and Xiaomin Guo

submission deadline 1 Jul 2026 | Viewed by 261 | Submission Open

Keywords: animal disease; innate immunity; gut microbiota; gut barrier; immune homeostasis

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Feature Papers in 'Conservation Biology and Biodiversity' (2nd Edition)

edited by

Ettore Randi

submission deadline 1 Jul 2026 | Viewed by 118 | Submission Open

Keywords: population genomics and diversity; heterozygosity; inbreeding; hybridization; adaptive introgression; natural selection; speciation; bottleneck and population fragmentation; genetic drift; gene flow; extinction risk; evolvability; paleogenomics; phylogeography; conservation units; ecotypes; phylogenetics and systematics; eDNA; non-invasive genetic sampling; environmental monitoring

(This special issue belongs to the Section Conservation Biology and Biodiversity)

Microbial Responses, Pollutant Toxicity Mechanisms, and Human Health Implications

edited by

Chao Song

, Zhongquan Jiang and

Jiale Chen

submission deadline 10 Jul 2026 | 1 articles | Viewed by 885 | Submission Open

Keywords: heavy metal and emerging pollutants; microbiology and plant physiology; aquatic biology; environmental chemistry; anthropogenic disturbances; machine learning; pangenome analysis; computational toxicology; human health

Ultrastructure and Function in In Vitro Cancer Models: From Morphology to Mechanism

edited by

Michela Relucenti

and

Katia Cortese

submission deadline 15 Jul 2026 | Viewed by 51 | Submission Open

Keywords: cancer; organoids; spheroids; transmission electron microscopy; scanning electron microscopy; focused ion beam (FIB)

(This special issue belongs to the Section Cancer Biology)

Plant Perception, Behavior, and Environmental Response Mechanisms

edited by

Silvia Guerra

and Bianca Bonato

submission deadline 15 Jul 2026 | Viewed by 47 | Submission Open

Keywords: plant perception; plant movement; social cognition; communication; plant behavior; climbing plants; interactions; plant– plant interactions; environment; plant– environment interactions

(This special issue belongs to the Section Plant Science)

Methods in Bioinformatics and Computational Biology

edited by

Xingjian Chen

submission deadline 25 Jul 2026 | Viewed by 256 | Submission Open

Keywords: bioinformatics; computational biology; machine learning in biomedicine; artificial intelligence; single-cell and spatial transcriptomics analysis; biological network analysis; high-throughput data analysis

Tissue and Organ Regeneration in Fish: Evolutionary Mechanisms

edited by Yujun Liang

submission deadline 30 Jul 2026 | 1 articles | Viewed by 4493 | Submission Open

Keywords: organ and tissue regeneration; regeneration mechanisms; progenitor cells; dedifferentiation; fishes; evolutionary adaptation; genetic regulation; signaling pathways; comparative genomics

(This special issue belongs to the Section Evolutionary Biology)

Plant Natural Products: Mechanisms of Action for Promoting Health

edited by

Francisco Les

and

Guillermo Cásedas

submission deadline 31 Jul 2026 | 12 articles | Viewed by 28689 | Submission Open

Keywords: phytochemicals; bioactivity; therapeutics; mechanisms; health promotion; metabolism; enzyme activity; bioactive compounds; pharmacognosy; plant extracts; polyphenols; ethnopharmacology; essential oils; aromatic plants; antioxidants; natural products

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Dendrochronology in Arid and Semiarid Regions

edited by

Zongshan Li

submission deadline 31 Jul 2026 | 6 articles | Viewed by 13315 | Submission Open

Keywords: tree rings; growth– climate response; dendrochronology; dendroecology; dryland regions

(This special issue belongs to the Section Ecology)

Animal Models of Metabolic Diseases

edited by

Júlio Cezar De Oliveira

and

Melvin Khee Shing Leow

submission deadline 31 Jul 2026 | 7 articles | Viewed by 11206 | Submission Open

Keywords: experimental models; metabolic syndrome; insulin resistance; type 2 diabetes mellitus; obesity; dyslipidemia; hypertension; metabolic programming; DOHaD

(This special issue belongs to the Section Physiology)

Reproductive Physiology and Pathology in Livestock

edited by Claudio Gustavo Ustavo Barbeito and

Fabiano José Ferreira De Sant’Ana

submission deadline 31 Jul 2026 | 5 articles | Viewed by 7954 | Submission Open

Keywords: livestock; animal reproduction; reproductive biology; physiology and pathology of reproduction; experimental models; non-conventional species; biotechnology; immunology

(This special issue belongs to the Section Developmental and Reproductive Biology)

Phytoplasmas: Molecular Characterization and Host–Pathogen Interactions (2nd Edition)

edited by

Wei Wei

submission deadline 31 Jul 2026 | 5 articles | Viewed by 7247 | Submission Open

Keywords: molecular diagnosis and epidemiology; host-phytoplasma interactions; genetic diversity; taxonomy and classification; ecology and evolution; insect vectors; disease management; phytoplasma genomics and other omics studies

(This special issue belongs to the Section Microbiology)

Human Leukocyte Antigen (HLA)—Antigen Interactions in Vaccine Development

edited by

Apostolos P. Georgopoulos

submission deadline 31 Jul 2026 | 4 articles | Viewed by 7080 | Submission Open

Keywords: HLA; vaccine; antigen; antibody; cancer; binding affinity; biophysical modeling; lymphocytes

Ecological Regulation of Forest and Grassland Pests

edited by

Dun Wang

and Liangjian Qu

submission deadline 31 Jul 2026 | 6 articles | Viewed by 6759 | Submission Open

Keywords: forest and grassland pests; ecological regulation; sustainable IPM; biological control; forest management

(This special issue belongs to the Section Ecology)

Milk Oligosaccharides: Biological Functions and Application Prospects

edited by

Chunsheng Jin

submission deadline 31 Jul 2026 | 3 articles | Viewed by 6670 | Submission Open

Keywords: milk oligosaccharides; colostrum; HMO; gut microbiota; immune modulator; prebiotics

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Unraveling the Molecular Mechanisms of Development and Stress Tolerance in Vegetables

edited by

Zhansheng Li

Jin Xu

and

Ying Li

submission deadline 31 Jul 2026 | 3 articles | Viewed by 6620 | Submission Open

Keywords: vegetable development; molecular mechanisms; stress tolerance; genetic regulation; epigenetic regulation; biochemical regulation; sustainable agriculture; environmental stress; growth adaptation; crop yield; gene editing; cellular engineering

(This special issue belongs to the Section Plant Science)

The Biodiversity and Ecosystem Dynamics of Deep-Sea Hydrothermal Vents

edited by

Xiang Zeng

and Yadong Zhou

submission deadline 31 Jul 2026 | 4 articles | Viewed by 5668 | Submission Open

Keywords: deep-sea hydrothermal vents; biodiversity; microbiome; biological resources; marine biology

(This special issue belongs to the Section Marine Biology)

The Relationship Between Water Quality and Aquatic Organisms (2nd Edition)

edited by Dong Zhang,

Ming Duan

Miao Wang

Xiangsheng Hong

and Mengmeng Yi

submission deadline 31 Jul 2026 | 4 articles | Viewed by 5494 | Submission Open

Keywords: aquatic animals; water quality; phytoplankton; zooplankton; microorganisms; physiology

Unraveling the Tumor-Immune Microenvironment Using Transcriptomics

edited by

Leonardo Oliveira Reis

submission deadline 31 Jul 2026 | 2 articles | Viewed by 5263 | Submission Open

Keywords: tumor-immune microenvironment; immune cells; tumor cells; stromal cells; signaling molecules; extracellular matrix (ECM); vascular network

(This special issue belongs to the Section Cancer Biology)

Cellular and Molecular Mechanisms in Sensory–Metabolic Integration: From Signaling Pathways to Systemic Regulation

edited by

Antonino Maniaci

, Giovanni Giurdanella, Mohamed Amin Zaoual and

Caterina Gagliano

submission deadline 31 Jul 2026 | 3 articles | Viewed by 4683 | Submission Open

Keywords: multisensory disorders; metabolic dysfunction; systemic health; sensory impairments; metabolic syndrome; neurometabolic pathways; vision impairment; hearing loss; vestibular disorders; olfactory dysfunction; gustatory dysfunction; somatosensory impairment; energy homeostasis; integrative medicine

(This special issue belongs to the Section Biochemistry and Molecular Biology)

The Future of Marine Megafauna

edited by

Vincent L. Bels

and

John R. Turner

submission deadline 31 Jul 2026 | 3 articles | Viewed by 4015 | Submission Open

Keywords: marine biodiversity; marine megafauna; anthropogenic impacts; conservation biology; marine ecosystems; behavioural ecology; marine protected areas (MPAs); ecological resilience; evolutionary biology; species recovery strategies

(This special issue belongs to the Section Zoology)

Osteoblast Differentiation in Health and Disease

edited by

Nadia Calabriso

and Maria Annunziata Carluccio

submission deadline 31 Jul 2026 | 3 articles | Viewed by 3183 | Submission Open

Keywords: osteogenesis; mesenchymal stem cells; osteoblast; osteoblast differentiation; bone diseases; transcription factors; epigenetics; extracellular vesicles; inflammatory mediators; bioactive natural compounds

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Tickborne Diseases and Their Vectors

edited by Moses Sibusiso Mtshali

submission deadline 31 Jul 2026 | 2 articles | Viewed by 2192 | Submission Open

Keywords: ticks; tickborne pathogens; epidemiology of tickborne diseases; zoonotic diseases; molecular diagnosis; genetic diversity; immunology; vector control and mapping

(This special issue belongs to the Section Infection Biology)

2nd Edition: Conservation and Evolution of Wildlife in the Context of Climate Change and Human Population Growth

edited by

Wen Bo Liao

submission deadline 31 Jul 2026 | 2 articles | Viewed by 1839 | Submission Open

Keywords: changes; local temperature; adaptation; evolution; animals; plants

(This special issue belongs to the Section Behavioural Biology)

Advances in Redox Metabolism and Cellular Homeostasis

edited by

Alexios Vlamis-Gardikas

and

Jianqiang Xu

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1708 | Submission Open

Keywords: oxidative stress; peroxiredoxins; hydrogen peroxide; redox regulation; thiol modification; reactive oxygen species; iron sulfur clusters; redox signaling

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Advances in Microbial Enzyme Engineering

edited by

Thanongsak Chaiyaso

and Kamon Yakul

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1354 | Submission Open

Keywords: microbial enzyme engineering; lignocellulolytic enzymes; biorefinery applications; protein engineering; enzyme-based biomass conversion; synthetic biology

(This special issue belongs to the Section Microbiology)

Advances in Foodborne Pathogens

edited by Qiming Chen

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1014 | Submission Open

Keywords: foodborne pathogens; contamination mechanisms; infection mechanisms; detection assays; risk assessment; antibacterial agents or materials

(This special issue belongs to the Section Microbiology)

Heavy Metal Pollution and Bioremediation: Application and Mechanism

edited by

Guangxu Zhu

, Ruiyu Lin and Rongfei Wei

submission deadline 31 Jul 2026 | 1 articles | Viewed by 874 | Submission Open

Keywords: heavy metal pollutants; microbial remediation; phytoremediation; animal remediation; plant– soil– microbe interactions; enhanced remediation; combined remediation; hyperaccumulator plants; microbial-induced calcium carbonate precipitation

(This special issue belongs to the Section Toxicology)

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