Advances in Cardiac and Vascular Biology: From Mechanisms to Pathophysiology

A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Physiology".

Deadline for manuscript submissions: 31 August 2026 | Viewed by 164

Special Issue Editors


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Guest Editor
Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, School of Medicine, Yale University, New Haven, CT, USA
Interests: cardiovascular diseases; vascular remodeling; inflammation; fluid shear stress; metabolism
Heart, Lung, Blood, and Vascular Medicine Institute, Department of Medicine, Division of Cardiology, University of Pittsburgh, Pittsburgh, PA, USA
Interests: induced pluripotent stem cell model; inherited cardiomyopathies; calcium handling; genome editing; cardiac arrhythmias; cardiac aging; heart failure

Special Issue Information

Dear Colleagues,

The heart and blood vessels form a highly integrated system, governed by intricate molecular and cellular interactions that are essential for maintaining cardiovascular functions and homeostasis. Disruptions in these processes contribute to a broad spectrum of cardiovascular diseases, the leading cause of morbidity and mortality worldwide.

This Special Issue aims to enhance our understanding of cardiovascular pathophysiology at both the molecular and cellular levels, encouraging new perspectives in basic cardiovascular research. It will focus on fundamental biological mechanisms that drive cardiac and vascular development, homeostasis, and disease progression. The emphasis will be on novel insights into signaling pathways, cellular crosstalk, genomic and epigenomic regulation, and metabolic adaptations in cardiac and vascular physiology and pathology.

Key topics of interest include, but are not limited to, the following:

  • Endothelial and smooth muscle cell dynamics;
  • Cardiomyocyte biology;
  • Stem cell biology and tissue regeneration;
  • Extracellular matrix remodeling;
  • Mechanotransduction;
  • Metabolic reprogramming;
  • Genomic and epigenomic regulation;
  • Autophage and protein homeostasis;
  • The role of non-coding RNAs in cardiovascular regulation.

We invite the submission of original studies and comprehensive reviews that illuminate these critical biological processes.

Dr. Hanqiang Deng
Dr. Haodi Wu
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cardiovascular biology
  • molecular mechanisms
  • cellular signaling
  • epigenomic regulation
  • vascular remodeling
  • metabolic reprogramming
  • cardiac pathophysiology

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Published Papers

This special issue is now open for submission.
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