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Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Genomic Analysis of Drug-Resistant Pathogens

edited by

Erica Diani

submission deadline 28 Feb 2026 | 3 articles | Viewed by 10949 | Submission Open

Keywords: multi-drug resistant; mutation; bacteria; NGS; sequencing; mobile genetics elements; gene transfer

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

The Worldwide Problem of Antifungal Resistance: From Basic to Clinic

edited by

Max Carlos Ramírez-Soto

and

Alexandro Bonifaz

submission deadline 28 Feb 2026 | 2 articles | Viewed by 9392 | Submission Open

Keywords: antifungal agents; antifungal resistance; fungal pathogens; pharmacology; therapeutic use

Antimicrobial Stewardship and Infection Prevention in Intensive Care Unit

edited by

Mihai Sava

and

Majdi N. Al-Hasan

submission deadline 28 Feb 2026 | 4 articles | Viewed by 9061 | Submission Open

Keywords: antimicrobial stewardship; infection prevention; intensive care unit (ICU); antimicrobial resistance; healthcare-associated infections; patient safety

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Virulence, Antimicrobial Resistance and Biofilm Production in Veterinary, Zoonotic and Food-Related Pathogens

edited by Óscar Mencía-Ares, Paula Fernández-Gómez and

Sonia Martinez

submission deadline 28 Feb 2026 | 7 articles | Viewed by 7817 | Submission Open

Keywords: animal health; antimicrobial resistance; biofilm; food-borne pathogens; microbiology; pathogenicity; public health; veterinary pathogens; virulence; zoonosis

(This special issue belongs to the Section Antibiotics in Animal Health)

Emerging Challenges in Food Safety: Addressing Antimicrobial Resistance, Virulence Factors, and Biofilm Formation in Food-Borne Pathogens

edited by

Liora Mihaela Colobățiu

, Marian Mihaiu and

Zorita Diaconeasa

submission deadline 28 Feb 2026 | 3 articles | Viewed by 7264 | Submission Open

Keywords: antimicrobial resistance; food-borne pathogens; food safety; virulence factors; biofilm formation; resistance genes; food production; public health; molecular epidemiology; infection control

Antibacterial, Antibiofilm and Anti-virulence Activity Research of Both Natural and Synthetic Products, 2nd Edition

edited by

Eliana De Gregorio

and

Anna Esposito

submission deadline 28 Feb 2026 | 2 articles | Viewed by 7217 | Submission Open

Keywords: antimicrobial agent; antibiofilm agent; synergy between new antimicrobial products and conventional antibiotics; anti-virulence agent; mechanism of drug action; repurposing of approved drugs as antibacterial agent; biofilms; virulence factors

(This special issue belongs to the Section Plant-Derived Antibiotics)

Antibiotics and the Evolution of Resistance: Insights into Horizontal Gene Transfer

edited by

Günther Koraimann

and

Elisabeth Grohmann

submission deadline 28 Feb 2026 | 2 articles | Viewed by 4496 | Submission Open

Keywords: antibiotic resistance spread and evolution; pathogens; one health; plasmids; integrative conjugative elements; bacteriophages; conjugative transfer; transduction

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antibiotic Therapy in Respiratory Tract Infections (RTIs)

edited by Ágnes Tóth and

Attila Csaba Nagy

submission deadline 28 Feb 2026 | 3 articles | Viewed by 3522 | Submission Open

Keywords: antibiotic therapy; respiratory tract infections; clinical guidelines; prescribing practices; antibacterial resistance; antimicrobial stewardship

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antibacterial and Antibiofilm Properties of Biomaterial

edited by

Ziba Najmi

and Alessandro Calogero Scalia

submission deadline 28 Feb 2026 | 2 articles | Viewed by 3497 | Submission Open

Keywords: biomaterials surfaces; coating; biofilm formation; biofilm eradication

(This special issue belongs to the Section Antibiofilm Strategies)

Progress and Challenges in the Antibiotic Treatment of Infections

edited by Marina Bubonja-Sonje

submission deadline 28 Feb 2026 | 3 articles | Viewed by 3263 | Submission Open

Keywords: antimicrobial therapy; antimicrobial stewardship; antimicrobial resistance; rapid microbiological diagnostics

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Epidemiology and Genomics of Antimicrobial Resistance of Difficult-to-Treat Pathogens

edited by Simone Ambretti

submission deadline 28 Feb 2026 | 3 articles | Viewed by 2388 | Submission Open

Keywords: antimicrobial resistance; difficult-to-treat pathogens; epidemiology; genomics; MRSA; VRE; ESBL; CRE; CRAB; MDR pseudomonas aeruginosa

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Genetic Mechanisms of Bacterial Survival: Antibiotic Resistance and Defense Strategies

edited by

Caio Augusto Martins Aires

and

Thiago Pavoni Gomes Chagas

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1493 | Submission Open

Keywords: antimicrobial resistance mechanisms; disinfectant and antiseptic resistance; biofilm formation; genomic insights; horizontal gene transfer

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antimicrobial Stewardship in the Management of Bloodstream Infections

edited by

Zoran Todorovic

Gordana Dragović

and Saša Trailović

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1291 | Submission Open

Keywords: bloodstream infections; antimicrobial drugs; immunodeficiency; sepsis; antimicrobial resistance; therapeutic drug monitoring

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Advances in Antimicrobial Strategies to Control Listeria in Food and Clinical Settings

edited by

José Ramos-Vivas

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1253 | Submission Open

Keywords: Listeria monocytogenes; antimicrobial agents; biofilms; probiotic strains; mechanisms of resistance

Pioneering the Microbiome—Infections, Inflammation, Inflammatory Bowel Disease and the Role of Antibiotic Therapy

edited by

Gaurav Agrawal

and

Roger Pickup

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1202 | Submission Open

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Epidemiology and Pathogenomics of the Corynebacterium Genus

edited by

Vasco Azevedo

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1107 | Submission Open

Keywords: Corynebacterium; epidemiology; genomics; diagnostic; vaccine; drugs

Urinary Tract Infections: Diagnosis, Etiology, Antibiotic Treatment, and Current Trends in Antimicrobial Resistance

edited by Michael Mihailov Petrov

submission deadline 28 Feb 2026 | 2 articles | Viewed by 1016 | Submission Open

Keywords: urinary tract infections (UTIs); etiology; epidemiology; microbiological diagnosis; antimicrobial resistance; treatment; molecular genetic methods; resistotypes; rapid identification; uropathogens

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Pharmacologic Management of MDR Respiratory and Bacteraemic Infections

edited by

Demosthènes A. Makris

and Konstantinos D. Mantzarlis

submission deadline 28 Feb 2026 | Viewed by 469 | Submission Open

Keywords: pneumonia; bacteraemia; intensive care; MDR infections; antibiotics

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Optimization of Antimicrobial Stewardship in Public Health, 2nd Edition

edited by

Aoife Fleming

and

Vito D'Andrea

submission deadline 28 Feb 2026 | Viewed by 296 | Submission Open

Keywords: antimicrobial stewardship; antimicrobial prescribing; antimicrobial surveillance; primary care; secondary care; long-term care; penicillin allergy; pharmacy; public health; general practice; point-of-care testing; qualitative research

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antimicrobial Activity of Different Plant Extracts, Plant-Derived Compounds and Synthetic Derivatives of Natural Compounds on Pathogenic Microorganisms, 3rd Edition

edited by

Anna Duda-Madej

Joanna Kozłowska

and

Katarzyna Wińska

submission deadline 28 Feb 2026 | Viewed by 265 | Submission Open

Keywords: antimicrobial activity; plant extracts; plant-derived compounds; synthetic derivatives; flavonoids; multidrug resistance; pathogenic strains

(This special issue belongs to the Section Plant-Derived Antibiotics)

Impact of Plant-Derived Products as Novel Antimicrobial Agents

edited by Eleonora Spinozzi

submission deadline 28 Feb 2026 | Viewed by 253 | Submission Open

Keywords: natural compounds; plant bacteria; fungal infections; antimicrobial

(This special issue belongs to the Section Plant-Derived Antibiotics)

Natural Extracts as Antimicrobial Agents in Infectious Disease Therapy

edited by

Francesca Mariani

submission deadline 28 Feb 2026 | Viewed by 241 | Submission Open

Keywords: medicinal plants; phytocomplexes; essential oils; intracellular bacteria; bacterial cell wall; minimal inhibitory concentration (MIC); minimal bactericidal concentration (MBC); antiadhesive properties; bacterial biofilm; minimal biofilm-inhibiting concentration (MBIC)

(This special issue belongs to the Section Plant-Derived Antibiotics)

Current Advances and Innovations in Anti-Infective Agents Discovery

edited by

Valnês da Silva Rodrigues-Junior

submission deadline 28 Feb 2026 | 1 articles | Viewed by 203 | Submission Open

Keywords: drug development; antiviral; antibacterial; antifungal; antiparasitic

(This special issue belongs to the Section Novel Antimicrobial Agents)

New Advances in Antibiotic Therapy in the Gastroenterology Field

edited by

Giuseppe Guido Maria Scarlata

and Francesca Serapide

submission deadline 28 Feb 2026 | Viewed by 181 | Submission Open

Keywords: antibiotic therapy; antimicrobial resistance; gastroenterology; infectious diseases; microbiology; gut– liver axis; antimicrobial stewardship; infection control; biomarkers; diagnosis; epidemiology

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antimicrobial Resistance and Pharmacotherapy in the Elderly: Challenges and Innovations in Medication Management

edited by

Tiago Lima

, Ana Marta Lavrador and Ana C. Cabral

submission deadline 28 Feb 2026 | Viewed by 179 | Submission Open

Keywords: antimicrobial resistance; elderly pharmacotherapy; multidrug-resistant infections; medication management; antimicrobial stewardship; polypharmacy; geriatrics; drug& ndash; microbiota interactions

Bacteriocins and Antimicrobial Peptides in the Era of Antimicrobial Resistance

edited by

Umme Laila Urmi

and

Shyam Kumar Mishra

submission deadline 28 Feb 2026 | Viewed by 166 | Submission Open

Keywords: bacteriocins; antimicrobial peptides; antimicrobial resistance; multidrug-resistant pathogens; novel therapeutics

Resistance, Treatment and Prevention of ESKAPE Pathogens

edited by

Steven E. Fiester

and

William Penwell

submission deadline 28 Feb 2026 | Viewed by 151 | Submission Open

Keywords: antibiotic resistance; prevention methods; treatment strategies; ESKAPE pathogens

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Molecular Detection and Characterization of Multidrug Resistance in Staphylococci

edited by

Kunyan Zhang

submission deadline 28 Feb 2026 | Viewed by 151 | Submission Open

Keywords: staphylococcal species (Staphylococcus spp.); staphylococci; Staphylococcus aureus; methicillin-susceptive S. aureus (MSSA); methicillin-resistant S. aureus (MRSA); coagulase-negative staphylococci (CoNS); antibiotic resistance; multidrug-resistant (MDR); molecular evolution; epidemiology; characterization; and pathogenicity of staphylococci; antimicrobial stewardship; infection prevention and control

Antimicrobial Resistance at the Human–Animal Interface: Surveillance, Epidemiology, Modelling and Risk Assessment

edited by

Alessandro Bellato

and

Alessandro Mannelli

submission deadline 28 Feb 2026 | Viewed by 131 | Submission Open

Keywords: antimicrobial resistance (AMR); human– animal interface; One Health; surveillance; epidemiology; risk assessment; veterinary medicine; zoonotic transmission

Peptide-Based Drugs in the Era of Antimicrobial Resistance

edited by

Santos Ramírez Carreto

and

Juana María Jiménez-Vargas

submission deadline 28 Feb 2026 | Viewed by 128 | Submission Open

Keywords: antimicrobial resistance; antimicrobial activity; novel antimicrobial peptides; structure– activity relationship; bionanotechnology; improvement of biological stability; rational drug design; optimization of drug delivery systems

Optimizing Antimicrobial Use: Antimicrobial Stewardship and Surveillance, 2nd Edition

edited by

Jesus Ruiz-Ramos

submission deadline 28 Feb 2026 | Viewed by 109 | Submission Open

Keywords: antimicrobial stewardship; antimicrobial cycling; antimicrobial resistance; decision support; antibiotic optimization; antibiotic therapy

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Epidemiology of and Antibiotic Therapy for Helicobacter pylori Infection

edited by

Peter Birinyi

submission deadline 28 Feb 2026 | Viewed by 66 | Submission Open

Keywords: Helicobacter pylori infection; bismuth citrate; metronidazole; tetracycline; amoxicillin; clarithromycin; proton pump inhibitor; amoxicillin

Antibiotic Resistance and Antimicrobial Use in Pediatric Wards

edited by

Evanthia Botsa

and

Spyridon Karageorgos

submission deadline 28 Feb 2026 | Viewed by 47 | Submission Open

Keywords: antimicrobial resistance (AMR); pediatric infectious diseases; hospital-acquired infections; antimicrobial stewardship; multidrug-resistant organisms (MDROs); diagnostic innovations in pediatrics

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

A Themed Issue in Honor of Professor Stefan Schwarz—Antimicrobial Resistance of Bacteria of Animal Origin: Diagnostics, Monitoring, Mechanisms and Epidemiology

edited by

Igor Loncaric

and Séamus Fanning

submission deadline 1 Mar 2026 | Viewed by 372 | Submission Open

Keywords: antimicrobial resistance; animals; resistance genes; mechanism of resistance; MRSA; ESBL; staphylococci; enterobacterales

Antibiotic Resistance in Bacterial Isolates of Animal Origin

edited by

Tomasz Jarzembowski

and

Lidia Piechowicz

submission deadline 5 Mar 2026 | Viewed by 70 | Submission Open

Keywords: zoonotic infection; resistance genes; “ one health concept” ; Salmonella enterica; Campylobacter jejuni; enterohemorrhagic Escherichia coli; Enterococcus faecalis

(This special issue belongs to the Section Antibiotics in Animal Health)

Antibiotic Stewardship Implementation Strategies

edited by

Massimo Sartelli

submission deadline 15 Mar 2026 | 5 articles | Viewed by 5498 | Submission Open

Keywords: antibiotic stewardship; implementation; hospital settings

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antibiotics for Primary Care Practice

edited by Reza Nassiri

submission deadline 15 Mar 2026 | Viewed by 505 | Submission Open

Keywords: primary care practice; nursing home practice; remote practice; antibiotic prescription habits; antibiotic resistance in clinical practice; public health consequences of antibiotic resistance; antibiotics stewardship practices; elements of safe practice

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Surveillance of Carbapenem-Resistant Microbes and Strategies to Combat Them

edited by Daniela Cejas and Marcela Radice

submission deadline 15 Mar 2026 | Viewed by 217 | Submission Open

Keywords: antibiotic resistance; epidemiology; carbapenemases; carbapenem resistance; enterobacterales; acinetobacter baumannii; resistance plasmids; surveillance; genomics; high-risk clones

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Challenges and Emerging Strategies to Tackle the Global Burden of Antimicrobial Resistance

edited by

Tomislav Meštrović

submission deadline 20 Mar 2026 | 4 articles | Viewed by 14332 | Submission Open

Keywords: antimicrobial resistance (AMR); global burden of AMR; AMR in the context of public and global health; diagnostic and treatment of AMR; new approaches to AMR surveillance; antibiotic stewardship; local and global policy initiatives on AMR; prevention of AMR

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antibiotic Resistance in Hospital-Acquired Infections

edited by Andreea-Loredana Golli,

Ovidiu Zlatian

and

Alice Elena Ghenea

submission deadline 20 Mar 2026 | 4 articles | Viewed by 5694 | Submission Open

Keywords: healthcare-associated infections; multi-drug resistance; epidemiology; antimicrobial therapy; patient outcomes; infection prevention and control strategies

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Hospital-Acquired Infections, Multidrug Resistant (MDR) Bacteria, AI, and Alternative Approaches to Antibiotic Therapy

edited by

Susu Zughaier

and

Nayeem Ahmad

submission deadline 20 Mar 2026 | Viewed by 68 | Submission Open

Keywords: antimicrobial resistance; hospital-acquired infections; multidrug resistant; artificial intelligence; nosocomial infection; molecular mechanism of resistant bacteria

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Linking Genomic Mutations to Antimicrobial Resistance and Virulence

edited by

Eduardo Alvarez Duarte

submission deadline 30 Mar 2026 | Viewed by 74 | Submission Open

Keywords: antifungal resistance; antifungal drugs; antibiotics; resistance; antimicrobial resistance; genetic mutations; SNP

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Optimizing Antibiotic Use and Consumption: Integrating Surveillance, Policy and Practice

edited by

Paola Lichtenberger

submission deadline 30 Mar 2026 | Viewed by 43 | Submission Open

Keywords: infectious disease; antimicrobial stewardship; antibiotic use; antimicrobial consumption; point prevalence survey

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antimicrobials Use: Clinical Safety to Environmental Risk—Learning from One Health Approach

edited by

Anabela Almeida

Leonor M. Meisel

and

Ana Fortuna

submission deadline 31 Mar 2026 | 8 articles | Viewed by 35910 | Submission Open

Keywords: antimicrobials; antifungals; antiviral; environment; antimicrobial resistance; pharmacokinetics; risk-assessment; prioritisation; One-Health

Antibiotics as Major Disruptors of Gut Microbiota

edited by

Gábor Ternák

submission deadline 31 Mar 2026 | 6 articles | Viewed by 28477 | Submission Open

Keywords: microbiome; gut flora; development of gut flora; dysbiosis; antibiotics; antibiotic classes; antibiotic consumption; gut– brain axis; short-chain fatty acids; metabolom; mediator molecules; composition of gut flora

Membranes to Fight Drug-Resistant Microbes

edited by

Nermina Malanovic

submission deadline 31 Mar 2026 | 6 articles | Viewed by 20405 | Submission Open

Keywords: antimicrobial peptides; membrane-active compounds; mode of action; lipidoids; vaccines

(This special issue belongs to the Section Antimicrobial Peptides)

Antibiotics: Fighting Disease and Promoting Health by Embracing the Two Sides of the Same Coin

edited by

Chrysoula Voidarou

Elisavet Stavropoulou

and

Eugenia Bezirtzoglou

submission deadline 31 Mar 2026 | 2 articles | Viewed by 7679 | Submission Open

Keywords: antibiotics; probiotics; antibacterial activity; functional food; natural compounds; natural antimicrobials; microbiome; antimicrobial resistance; resistome

(This special issue belongs to the Section The Global Need for Effective Antibiotics)

Companion Animals: Antimicrobial Resistance in Bacterial and Fungal Pathogens Associated with Skin and Ear Infections

edited by

Dominik Łagowski

and

Ewelina Czyzewska-Dors

submission deadline 31 Mar 2026 | 4 articles | Viewed by 7129 | Submission Open

Keywords: dermatophytes; Candida; companion animals; drug susceptibility; Malassezia; mechanisms of resistance; molecular detection; Pseudomonas; Staphylococcus; One Health; MDR; veterinary

(This special issue belongs to the Section Antibiotics in Animal Health)

Genomic Insights and Implications of Emerging Antimicrobial Resistance

edited by

Daniela Bencardino

and

Christian Berens

submission deadline 31 Mar 2026 | 4 articles | Viewed by 4881 | Submission Open

Keywords: antibiotic-resistance; molecular typing; genomic technologies; high-threat pathogens; epidemiological surveillance; emerging and re-emerging infectious diseases; one health approach

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antibiotics Resistance in Animals and the Environment, 2nd Edition

edited by

Anil Poudel

submission deadline 31 Mar 2026 | 2 articles | Viewed by 3838 | Submission Open

Keywords: antimicrobial resistance; environment; epidemiology; genomics; multi-drug resistance; sympatric; wildlife

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

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