Exploring Synthetic Organic Chemistry to Combat Pathogenic Infections
A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Novel Antimicrobial Agents".
Deadline for manuscript submissions: 30 April 2026 | Viewed by 4
Special Issue Editors
Interests: synthetic organic chemistry; medicinal and pharmaceutical chemistry; anti-inflammatory synthesis of medicinal compounds; organic synthesis; heterocyclic chemistry; synthetic medicinal chemistry; heterocyclic compounds synthesis
Special Issues, Collections and Topics in MDPI journals
Interests: medicinal chemistry; drug design; organic synthesis; heterocyclic compounds; biological activity; SAR; ADME; lipophilicity; PCA; K-means clustering; peptide chemistry
Special Issues, Collections and Topics in MDPI journals
Interests: chemically synthetized and/or modified antimicrobial molecules; antimicrobial potential testing; antimicrobial resistance; molecular docking; molecular descriptors
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The global rise in antimicrobial resistance has intensified the need for new and effective strategies to treat infectious diseases. While traditional antibiotics continue to lose efficacy, synthetic organic chemistry emerges as a powerful tool in the discovery and development of novel antimicrobial agents.
This Special Issue, titled “Exploring Synthetic Organic Chemistry to Combat Pathogenic Infections”, aims to showcase recent progress in the synthesis of bioactive compounds designed to target resistant and emerging pathogens. We invite original research articles, reviews, and short communications that demonstrate how synthetic methodologies can be harnessed to address urgent medical needs.
Topics of interest include, but are not limited to, the following:
- Synthesis of novel antimicrobial agents.
- Synthetic modifications of natural products.
- Structure–activity relationship (SAR) and/or molecular docking studies for antimicrobial molecules.
- Biological evaluation of the antimicrobial potential of new compounds.
- Multifunctional and resistance-bypassing compounds.
- Targeted drug delivery strategies involving new synthetic molecules.
Through this Special Issue, we seek to highlight the essential role of synthetic chemistry in the development of next-generation antimicrobials and to encourage collaboration between chemists, microbiologists, and clinicians.
We look forward to your valuable contributions.
Dr. Cătălin Araniciu
Dr. Ioana Ionuț
Dr. Gabriel Marc
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- synthetic organic chemistry
- antimicrobial agents
- structure–activity relationship (SAR)
- drug design
- molecular docking
- drug discovery
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