2026 December - 18 articles
12 November 2026
Background/Objectives: Type 2 diabetes (T2D) remission is increasingly attainable, but its implications for long-term microvascular risk remain uncertain. Methods: We critically appraised longitudinal reports relating achieved remission to subsequent...
Background: Obesity is increasingly recognized as a complex neuroimmunometabolic disorder rather than simply a consequence of excessive caloric intake. Chronic low-grade inflammation, oxidative stress, gut microbiota dysbiosis, hypothalamic dysfuncti...
Background/Objectives: GLP-1 receptor agonists (GLP-1RAs) and the dual GIP/GLP-1 receptor agonist tirzepatide reduce body weight, but their effects on muscle-related body-composition measures and physical function remain uncertain. We evaluated chang...
Background: Near-infrared autofluorescence (NIRAF) imaging has been widely used to identify parathyroid glands, but its impact on postoperative hypoparathyroidism and hypocalcemia remains controversial. This systematic review aims to evaluate the imp...
6 November 2026
Background: Well-differentiated pancreatic neuroendocrine tumors (PanNETs) develop in ~80% of patients with multiple endocrine neoplasia type 1 (MEN1) and remain the leading cause of MEN1-related mortality. Whether MEN1-associated PanNETs display dis...
Background/Objectives: Tubal ectopic pregnancy (TEP) remains a significant cause of maternal morbidity and mortality. Early access to pregnancy assessment units now allows for the detection of many TEPs at a stage at which they could potentially reso...
Background: In adults with type 1 diabetes (T1D), routine anthropometric assessment may not detect deterioration in muscle quality and cellular integrity. Body mass index (BMI) remains useful as a first-line screening tool but cannot distinguish lean...
Hypertension remains the leading preventable cause of cardiovascular disease and premature death worldwide. In the hypertensive state, renal and cardiovascular dysfunctions become entrenched in a self-perpetuating feedback loop, with immune cells eme...
Background: Cirrhosis is related to low levels of circulating insulin-like growth factor (IGF-1), which itself is caused by decreased synthesis by functional hepatic parenchyma. IGF-1 is also correlated with endogenous E2 and T in adolescents and dec...
Background: Roux-en-Y gastric bypass (RYGB) has been performed as a means for patients to lose weight through both a restrictive and malabsorptive process. This malabsorption can lead to nutritional deficiencies, especially those that require the duo...
Background/Objectives: The concurrent occurrence of papillary (PTC) and medullary (MTC) thyroid carcinoma within the same thyroid gland is an exceptionally rare clinical entity. We conducted a systematic review to synthesize available evidence on the...
Background/Objectives: To provide an updated overview of adrenal incidentaloma evaluation, characterize the principal imaging mimics across pediatric and adult populations, and propose a clinically actionable approach integrating endocrine assessment...
Background/Objectives: Although papillary thyroid carcinoma generally has an excellent prognosis, recurrence remains an important clinical problem in adolescents and young adults (AYA), while the prognostic value of molecular markers in this populati...
Introduction: Remogliflozin is a sodium–glucose cotransporter-2 inhibitor used for type 2 diabetes mellitus (T2DM), but its overall efficacy and safety remain fragmented. This updated systematic review and meta-analysis evaluated the efficacy a...
Background. Behavioral procrastination has traditionally been considered a self-regulatory and psychological phenomenon; however, growing evidence suggests that chronic procrastination may also contribute to adverse physical health outcomes through p...
Retinol-binding protein 4 (RBP4) is the primary carrier of retinol in the circulation and is produced mainly by the liver. Interest in RBP4 expanded after reports of elevated circulating levels in insulin-resistant mice and some human populations, le...
Background: Diabetes in males leads to hyperglycemia-induced oxidative stress and inflammation in the testis, resulting in apoptosis. Diabetes-induced testicular impairment has been linked to the implication with the gut–brain axis. Sodium buty...
Background: Obesity is strongly associated with type 2 diabetes, but clinical and metabolic characteristics vary among adults with obesity. This cross-sectional study evaluated whether routinely available nonglycemic variables could classify biochemi...
