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Bioengineering, Volume 9, Issue 11

2022 November - 119 articles

Cover Story: Freezing of gait (FOG) is a dramatic manifestation of Parkinson's disease (PD) that typically occurs at gait initiation (GI) and leads patients to falls and reduced quality and quantity of life. In our study, we explored the dynamic and kinematic changes related to PD and FOG during GI. Our results reveal a substantial impairment of feedforward motor programming during GI in PD patients, as shown by the reduction of centre of pressure movements during the imbalance phase. The FOG-specific deterioration of the unloading phase would suggest an impaired integration of motor programmes serving the GI, which could be partly compensated by cerebellar activity preserving temporal movement sequencing. Postural alterations seem to play a minor role in GI impairment in PD patients. View this paper
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Articles (119)

  • Article
  • Open Access
6 Citations
2,966 Views
15 Pages

Global Regulator AdpA_1075 Regulates Morphological Differentiation and Ansamitocin Production in Actinosynnema pretiosum subsp. auranticum

  • Siyu Guo,
  • Tingting Leng,
  • Xueyuan Sun,
  • Jiawei Zheng,
  • Ruihua Li,
  • Jun Chen,
  • Fengxian Hu,
  • Feng Liu and
  • Qiang Hua

Actinosynnema pretiosum is a well-known producer of maytansinoid antibiotic ansamitocin P-3 (AP-3). Growth of A. pretiosum in submerged culture was characterized by the formation of complex mycelial particles strongly affecting AP-3 production. Howev...

  • Article
  • Open Access
2 Citations
3,665 Views
18 Pages

Cultivation and Imaging of S. latissima Embryo Monolayered Cell Sheets Inside Microfluidic Devices

  • Thomas Clerc,
  • Samuel Boscq,
  • Rafaele Attia,
  • Gabriele S. Kaminski Schierle,
  • Bénédicte Charrier and
  • Nino F. Läubli

The culturing and investigation of individual marine specimens in lab environments is crucial to further our understanding of this highly complex ecosystem. However, the obtained results and their relevance are often limited by a lack of suitable exp...

  • Review
  • Open Access
18 Citations
5,320 Views
18 Pages

Stem Cell- and Cell-Based Therapies for Ischemic Stroke

  • Delia Carmen Nistor-Cseppentö,
  • Maria Carolina Jurcău,
  • Anamaria Jurcău,
  • Felicia Liana Andronie-Cioară and
  • Florin Marcu

Stroke is the second cause of disability worldwide as it is expected to increase its incidence and prevalence. Despite efforts to increase the number of patients eligible for recanalization therapies, a significant proportion of stroke survivors rema...

  • Article
  • Open Access
2 Citations
2,806 Views
11 Pages

Identification of Kinetic Abnormalities in Male Patients after Anterior Cruciate Ligament Deficiency Combined with Meniscal Injury: A Musculoskeletal Model Study of Lower Limbs during Jogging

  • Shuang Ren,
  • Xiaode Liu,
  • Haoran Li,
  • Yufei Guo,
  • Yuhan Zhang,
  • Zixuan Liang,
  • Si Zhang,
  • Hongshi Huang,
  • Xuhui Huang and
  • Yingfang Ao
  • + 2 authors

There is little known about kinetic changes in anterior cruciate ligament deficiency (ACLD) combined with meniscal tears during jogging. Therefore, 29 male patients with injured ACLs and 15 healthy male volunteers were recruited for this study to inv...

  • Article
  • Open Access
6 Citations
4,040 Views
13 Pages

Walking Speed Classification from Marker-Free Video Images in Two-Dimension Using Optimum Data and a Deep Learning Method

  • Tasriva Sikandar,
  • Sam Matiur Rahman,
  • Dilshad Islam,
  • Md. Asraf Ali,
  • Md. Abdullah Al Mamun,
  • Mohammad Fazle Rabbi,
  • Kamarul H. Ghazali,
  • Omar Altwijri,
  • Mohammed Almijalli and
  • Nizam U. Ahamed

Walking speed is considered a reliable assessment tool for any movement-related functional activities of an individual (i.e., patients and healthy controls) by caregivers and clinicians. Traditional video surveillance gait monitoring in clinics and a...

  • Review
  • Open Access
21 Citations
7,012 Views
17 Pages

COVID-19 Vaccines: An Updated Overview of Different Platforms

  • Dmitry Kudlay,
  • Andrey Svistunov and
  • Oleg Satyshev

Vaccination has been identified as a critical method of disease control in the context of the current COVID-19 pandemic. The goal of this review is to update information on vaccine development and to identify areas of concern that require further res...

  • Communication
  • Open Access
2 Citations
3,089 Views
10 Pages

Construction of HER2-Specific HIV-1-Based VLPs

  • Sofia A. Martins,
  • Joana Santos,
  • Sandra Cabo Verde,
  • João D. G. Correia and
  • Rita Melo

Virus-like particles (VLPs) are nanoplatforms comprised of one or more viral proteins with the capacity to self-assemble without viral genetic material. VLPs arise as promising nanoparticles (NPs) that can be exploited as vaccines, as drug delivery v...

  • Review
  • Open Access
45 Citations
5,369 Views
17 Pages

Chronic wounds are a silent epidemic threatening the lives of many people worldwide. They are associated with social, health care and economic burdens and can lead to death if left untreated. The treatment of chronic wounds is very challenging as it...

  • Article
  • Open Access
31 Citations
7,524 Views
9 Pages

Heart and Breathing Rate Variations as Biomarkers for Anxiety Detection

  • Florian Ritsert,
  • Mohamed Elgendi,
  • Valeria Galli and
  • Carlo Menon

With advances in portable and wearable devices, it should be possible to analyze and interpret the collected biosignals from those devices to tailor a psychological intervention to help patients. This study focuses on detecting anxiety by using a por...

  • Article
  • Open Access
74 Citations
9,639 Views
18 Pages

Empirical Study of Autism Spectrum Disorder Diagnosis Using Facial Images by Improved Transfer Learning Approach

  • Md Shafiul Alam,
  • Muhammad Mahbubur Rashid,
  • Rupal Roy,
  • Ahmed Rimaz Faizabadi,
  • Kishor Datta Gupta and
  • Md Manjurul Ahsan

Autism spectrum disorder (ASD) is a neurological illness characterized by deficits in cognition, physical activities, and social skills. There is no specific medication to treat this illness; only early intervention can improve brain functionality. S...

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Bioengineering - ISSN 2306-5354