Table of Contents
Bioengineering, Volume 5, Issue 3 (September 2018)
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Cover Story (view full-size image) A low percentage of novel drug candidates succeed and reach the end of the drug discovery pipeline. [...] Read more. A low percentage of novel drug candidates succeed and reach the end of the drug discovery pipeline. Emerging technologies involving the production of organoids from human pluripotent stem cells (hPSCs) and the use of organ-on-a-chip devices are showing great promise for developing a more reliable, rapid, and cost-effective drug discovery process. We address the current progress and challenges related to the process of obtaining organoids from hPSCs, as well as ways to create devices that will allow a precise examination of the in vitro effects generated by drug candidates in different organ systems. View this paper.