Next Article in Journal
Generation of Gellan Gum-Based Adipose-Like Microtissues
Next Article in Special Issue
Three-Dimensional (3D) Printed Microneedles for Microencapsulated Cell Extrusion
Previous Article in Journal
Comminution of Dry Lignocellulosic Biomass: Part II. Technologies, Improvement of Milling Performances, and Security Issues
Previous Article in Special Issue
Stem Cells and Engineered Scaffolds for Regenerative Wound Healing
Open AccessReview

Smart Wound Dressings for Diabetic Chronic Wounds

Bioengineering Department, Clemson University, Clemson, SC 29632, USA
Author to whom correspondence should be addressed.
Bioengineering 2018, 5(3), 51;
Received: 26 May 2018 / Revised: 13 June 2018 / Accepted: 19 June 2018 / Published: 26 June 2018
(This article belongs to the Special Issue Advances in Wound Healing Systems)
Given their severity and non-healing nature, diabetic chronic wounds are a significant concern to the 30.3 million Americans diagnosed with diabetes mellitus (2015). Peripheral arterial diseases, neuropathy, and infection contribute to the development of these wounds, which lead to an increased incidence of lower extremity amputations. Early recognition, debridement, offloading, and controlling infection are imperative for timely treatment. However, wound characterization and treatment are highly subjective and based largely on the experience of the treating clinician. Many wound dressings have been designed to address particular clinical presentations, but a prescriptive method is lacking for identifying the particular state of chronic, non-healing wounds. The authors suggest that recent developments in wound dressings and biosensing may allow for the quantitative, real-time representation of the wound environment, including exudate levels, pathogen concentrations, and tissue regeneration. Development of such sensing capability could enable more strategic, personalized care at the onset of ulceration and limit the infection leading to amputation. This review presents an overview of the pathophysiology of diabetic chronic wounds, a brief summary of biomaterial wound dressing treatment options, and biosensor development for biomarker sensing in the wound environment. View Full-Text
Keywords: diabetes; chronic wounds; smart wound dressing; biochemical sensor diabetes; chronic wounds; smart wound dressing; biochemical sensor
Show Figures

Figure 1

MDPI and ACS Style

Gianino, E.; Miller, C.; Gilmore, J. Smart Wound Dressings for Diabetic Chronic Wounds. Bioengineering 2018, 5, 51.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Search more from Scilit
Back to TopTop