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Bioengineering, Volume 10, Issue 12

2023 December - 104 articles

Cover Story: Obstruction of the LVAD flow path can occur when blood clots or tissue overgrowth form within the inflow cannula, pump body, or outflow graft, and it can lead to thrombus, embolism, and stroke. The impact of progressive pump inflow obstruction (PO) on the pressure and flow dynamics of the LVAD-supported heart was measured in a mock circulatory loop. Pressure and flow decreased with PO, shifting more of the flow through the aortic valve such that the total flow decreased by 6–11% and decreased the efficiency of the work of the native heart up to 60%. PO restricts diastolic flow through the LVAD, which reduces mitral inflow and decreases the strength and energy of the intraventricular vortices. The changes in flow architecture produced by PO include flow stasis and increased shear, which predispose the system to thromboembolic risk. View this paper
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Articles (104)

  • Article
  • Open Access
14 Citations
5,379 Views
17 Pages

Exoskeleton rehabilitation robots have been widely used in the rehabilitation treatment of stroke patients. Clinical studies confirmed that rehabilitation training with active movement intentions could improve the effectiveness of rehabilitation trea...

(This article belongs to the Section Biomedical Engineering and Biomaterials)
  • Review
  • Open Access
13 Citations
3,410 Views
20 Pages

The Autonomization Principle in Vascularized Flaps: An Alternative Strategy for Composite Tissue Scaffold In Vivo Revascularization

  • Yanis Berkane,
  • David M. Kostyra,
  • Theodoros Chrelias,
  • Mark A. Randolph,
  • Alexandre G. Lellouch,
  • Curtis L. Cetrulo,
  • Korkut Uygun,
  • Basak E. Uygun,
  • Nicolas Bertheuil and
  • Jérôme Duisit

Autonomization is a physiological process allowing a flap to develop neo-vascularization from the reconstructed wound bed. This phenomenon has been used since the early application of flap surgeries but still remains poorly understood. Reconstructive...

(This article belongs to the Section Regenerative Engineering)
  • Article
  • Open Access
3 Citations
2,870 Views
13 Pages

Improved Hypertension Risk Assessment with Photoplethysmographic Recordings Combining Deep Learning and Calibration

  • Jesús Cano,
  • Vicente Bertomeu-González,
  • Lorenzo Fácila,
  • Fernando Hornero,
  • Raúl Alcaraz and
  • José J. Rieta

Hypertension, a primary risk factor for various cardiovascular diseases, is a global health concern. Early identification and effective management of hypertensive individuals are vital for reducing associated health risks. This study explores the pot...

(This article belongs to the Special Issue Machine Learning for Biomedical Applications, Volume II)
  • Article
  • Open Access
12 Citations
3,373 Views
20 Pages

Among the various biochemical and biophysical inducers for neural regeneration, electrical stimulation (ES) has recently attracted considerable attention as an efficient means to induce neuronal differentiation in tissue engineering approaches. The a...

(This article belongs to the Section Nanobiotechnology and Biofabrication)
  • Article
  • Open Access
7 Citations
3,872 Views
12 Pages

Exploring the Role of Desmoplastic Physical Stroma in Pancreatic Cancer Progression Using a Three-Dimensional Collagen Matrix Model

  • Xiaoyu Song,
  • Yuma Nihashi,
  • Masamichi Yamamoto,
  • Daiki Setoyama,
  • Yuya Kunisaki and
  • Yasuyuki S. Kida

Pancreatic ductal adenocarcinoma (PDAC) is a refractory tumor with a poor prognosis, and its complex microenvironment is characterized by a fibrous interstitial matrix surrounding PDAC cells. Type I collagen is a major component of this interstitial...

(This article belongs to the Special Issue The New Frontiers of Artificial Organs Engineering)
  • Article
  • Open Access
2 Citations
2,782 Views
12 Pages

A Virtual Inner Ear Model Selects Ramped Pulse Shapes for Vestibular Afferent Stimulation

  • Joseph Chen,
  • Jayden Sprigg,
  • Nicholas Castle,
  • Cayman Matson,
  • Abderrahmane Hedjoudje and
  • Chenkai Dai

Bilateral vestibular deficiency (BVD) results in chronic dizziness, blurry vision when moving the head, and postural instability. Vestibular prostheses (VPs) show promise as a treatment, but the VP-restored vestibulo-ocular reflex (VOR) gain in human...

(This article belongs to the Section Regenerative Engineering)
  • Review
  • Open Access
605 Citations
46,505 Views
21 Pages

The integration of artificial intelligence (AI) into medical imaging has guided in an era of transformation in healthcare. This literature review explores the latest innovations and applications of AI in the field, highlighting its profound impact on...

(This article belongs to the Special Issue AI and Big Data Research in Biomedical Engineering)
  • Article
  • Open Access
3 Citations
3,008 Views
12 Pages

The treatment of critically ill patients remains an evolving and controversial issue. Mechanical circulatory support through a percutaneous approach for the management of cardiogenic shock has taken place in recent years. The combined use of IABP and...

(This article belongs to the Section Biomedical Engineering and Biomaterials)
  • Article
  • Open Access
3 Citations
5,688 Views
13 Pages

This study investigated clinical aspects of the traditional ear impression and 3D ear scanning techniques. Adult earmold-users and non-users participated in this study. The earmold-users also participated in the earmold comfort comparison study by we...

(This article belongs to the Section Regenerative Engineering)
  • Article
  • Open Access
8 Citations
2,310 Views
15 Pages

Non-Invasive Electroanatomical Mapping: A State-Space Approach for Myocardial Current Density Estimation

  • Erik Engelhardt,
  • Eric Elzenheimer,
  • Johannes Hoffmann,
  • Christy Meledeth,
  • Norbert Frey and
  • Gerhard Schmidt

Electroanatomical mapping is a method for creating a model of the electrophysiology of the human heart. Medical professionals routinely locate and ablate the site of origin of cardiac arrhythmias with invasive catheterization. Non-invasive localizati...

(This article belongs to the Section Biosignal Processing)
  • Article
  • Open Access
17 Citations
3,576 Views
18 Pages

Combined Edge Loss UNet for Optimized Segmentation in Total Knee Arthroplasty Preoperative Planning

  • Luca Marsilio,
  • Andrea Moglia,
  • Matteo Rossi,
  • Alfonso Manzotti,
  • Luca Mainardi and
  • Pietro Cerveri

Bone segmentation and 3D reconstruction are crucial for total knee arthroplasty (TKA) surgical planning with Personalized Surgical Instruments (PSIs). Traditional semi-automatic approaches are time-consuming and operator-dependent, although they prov...

(This article belongs to the Special Issue Artificial Intelligence in Surgery)
  • Article
  • Open Access
6 Citations
3,958 Views
10 Pages

Post-Operative Delirium and Cognitive Dysfunction in Aged Patients Undergoing Cardiac Surgery: A Randomized Comparison between Two Blood Oxygenators

  • Lorenzo Mantovani,
  • Elisa Mikus,
  • Elena Tenti,
  • Diego Sangiorgi,
  • Samantha Zannoni,
  • Andrea Cavallucci,
  • Letizia Ferroni,
  • Paolo Cimaglia,
  • Valentina Tolio and
  • Carlo Savini
  • + 1 author

In elderly patients undergoing cardiac surgery, extracorporeal circulation affects the incidence of post-operative delirium and cognitive impairment with an impact on quality of life and mortality. In this study, a new oxygenator system (RemoweLL 2)...

(This article belongs to the Section Biomedical Engineering and Biomaterials)
  • Article
  • Open Access
29 Citations
4,272 Views
16 Pages

Enhancing Skin Lesion Detection: A Multistage Multiclass Convolutional Neural Network-Based Framework

  • Muhammad Umair Ali,
  • Majdi Khalid,
  • Hanan Alshanbari,
  • Amad Zafar and
  • Seung Won Lee

The early identification and treatment of various dermatological conditions depend on the detection of skin lesions. Due to advancements in computer-aided diagnosis and machine learning approaches, learning-based skin lesion analysis methods have att...

(This article belongs to the Section Biosignal Processing)
  • Article
  • Open Access
4 Citations
3,406 Views
18 Pages

Non-contact remote photoplethysmography can be used in a variety of medical and healthcare fields by measuring vital signs continuously and unobtrusively. Recently, end-to-end deep learning methods have been proposed to replace the existing handcraft...

(This article belongs to the Section Biosignal Processing)
  • Perspective
  • Open Access
3 Citations
2,219 Views
11 Pages

A Fermentation State Marker Rule Design Task in Metabolic Engineering

  • Egils Stalidzans,
  • Reinis Muiznieks,
  • Konstantins Dubencovs,
  • Elina Sile,
  • Kristaps Berzins,
  • Arturs Suleiko and
  • Juris Vanags

There are several ways in which mathematical modeling is used in fermentation control, but mechanistic mathematical genome-scale models of metabolism within the cell have not been applied or implemented so far. As part of the metabolic engineering ta...

(This article belongs to the Section Biochemical Engineering)
  • Article
  • Open Access
1 Citations
2,348 Views
11 Pages

Revolutionizing Patient Monitoring in Age-Related Macular Degeneration: A Comparative Study on the Necessity and Efficiency of the AMD VIEWER

  • Hitoshi Tabuchi,
  • Tomofusa Yamauchi,
  • Toshihiko Nagasawa,
  • Hodaka Deguchi,
  • Mao Tanabe,
  • Hayato Tanaka and
  • Tsutomu Yasukawa

(1) Background: Age-related Macular Degeneration (AMD) is a critical condition leading to blindness, necessitating lifelong clinic visits for management, albeit with existing challenges in monitoring its long-term progression. This study introduced a...

(This article belongs to the Special Issue Biomedical Imaging and Data Analytics for Disease Diagnosis and Treatment)
  • Article
  • Open Access
23 Citations
4,471 Views
17 Pages

Traditional cervical cancer diagnosis mainly relies on human papillomavirus (HPV) concentration testing. Considering that HPV concentrations vary from individual to individual and fluctuate over time, this method requires multiple tests, leading to h...

(This article belongs to the Section Biomedical Engineering and Biomaterials)
  • Review
  • Open Access
10 Citations
5,453 Views
18 Pages

In the field of synthetic biology, rapid advancements in DNA assembly and editing have made it possible to manipulate large DNA, even entire genomes. These advancements have facilitated the introduction of long metabolic pathways, the creation of lar...

(This article belongs to the Section Cellular and Molecular Bioengineering)
  • Article
  • Open Access
10 Citations
2,932 Views
15 Pages

To evaluate the secretory function of adrenal incidentaloma, this study explored the usefulness of a contrast-enhanced computed tomography (CECT)-based radiomics model for distinguishing aldosterone-producing adenoma (APA) from non-functioning adrena...

(This article belongs to the Special Issue Recent Advances in Optical Imaging and Machine Learning in Biomedicine)
  • Article
  • Open Access
2 Citations
2,418 Views
21 Pages

Anti-Apoptosis Therapy for Meniscal Avascular Zone Repair: A Proof-of-Concept Study in a Lapine Model

  • Wenqiang Yan,
  • Yue Wu,
  • Fengyuan Zhao,
  • Ruilan Dai,
  • Yunan Zhou,
  • Dingge Liu,
  • Jin Cheng,
  • Xiaoqing Hu and
  • Yingfang Ao

In the present study, 24 rabbits were firstly used to evaluate the apoptosis index and matrix degeneration after untreated adult meniscal tears. Vertical tears (0.25 cm in length) were prepared in the avascular zone of the anterior horn. Specimens we...

(This article belongs to the Special Issue Stem/Progenitor Cells for Musculoskeletal Disease Modeling and Tissue Repair)
  • Article
  • Open Access
16 Citations
5,221 Views
24 Pages

A Critical Assessment of Generative Models for Synthetic Data Augmentation on Limited Pneumonia X-ray Data

  • Daniel Schaudt,
  • Christian Späte,
  • Reinhold von Schwerin,
  • Manfred Reichert,
  • Marianne von Schwerin,
  • Meinrad Beer and
  • Christopher Kloth

In medical imaging, deep learning models serve as invaluable tools for expediting diagnoses and aiding specialized medical professionals in making clinical decisions. However, effectively training deep learning models typically necessitates substanti...

(This article belongs to the Special Issue Artificial Intelligence (AI) for Medical Image Processing)
  • Article
  • Open Access
7 Citations
3,449 Views
22 Pages

The surge of diabetes poses a significant global health challenge, particularly in Oman and the Middle East. Early detection of diabetes is crucial for proactive intervention and improved patient outcomes. This research leverages the power of machine...

(This article belongs to the Section Biosignal Processing)
  • Article
  • Open Access
14 Citations
4,084 Views
24 Pages

Background: Breast cancer is arguably one of the leading causes of death among women around the world. The automation of the early detection process and classification of breast masses has been a prominent focus for researchers in the past decade. Th...

(This article belongs to the Special Issue Artificial Intelligence in Biomedical Imaging)
  • Article
  • Open Access
11 Citations
3,379 Views
14 Pages

Human Induced Pluripotent Spheroids’ Growth Is Driven by Viscoelastic Properties and Macrostructure of 3D Hydrogel Environment

  • Lucas Lemarié,
  • Tanushri Dargar,
  • Isabelle Grosjean,
  • Vincent Gache,
  • Edwin J. Courtial and
  • Jérôme Sohier

Stem cells, particularly human iPSCs, constitute a powerful tool for tissue engineering, notably through spheroid and organoid models. While the sensitivity of stem cells to the viscoelastic properties of their direct microenvironment is well-describ...

(This article belongs to the Section Biomedical Engineering and Biomaterials)
  • Article
  • Open Access
30 Citations
4,625 Views
14 Pages

Background: Accurate preoperative planning for total knee arthroplasty (TKA) is crucial. Computed tomography (CT)-based preoperative planning offers more comprehensive information and can also be used to design patient-specific instrumentation (PSI),...

(This article belongs to the Special Issue Advanced Engineering Technology in Orthopaedic Research)
  • Article
  • Open Access
25 Citations
4,267 Views
17 Pages

In response to the pressing need for robust disease diagnosis from gastrointestinal tract (GIT) endoscopic images, we proposed FLATer, a fast, lightweight, and highly accurate transformer-based model. FLATer consists of a residual block, a vision tra...

(This article belongs to the Special Issue Recent Advance of Machine Learning in Biomedical Image Analysis)
  • Article
  • Open Access
13 Citations
2,923 Views
16 Pages

Towards Optimizing Sub-Normothermic Machine Perfusion in Fasciocutaneous Flaps: A Large Animal Study

  • Yanis Berkane,
  • Alexandre G. Lellouch,
  • Guillaume Goudot,
  • Austin Shamlou,
  • Irina Filz von Reiterdank,
  • Marion Goutard,
  • Pierre Tawa,
  • Paul Girard,
  • Nicolas Bertheuil and
  • Korkut Uygun
  • + 4 authors

Machine perfusion has developed rapidly since its first use in solid organ transplantation. Likewise, reconstructive surgery has kept pace, and ex vivo perfusion appears as a new trend in vascularized composite allotransplants preservation. In autolo...

(This article belongs to the Section Biomedical Engineering and Biomaterials)
  • Article
  • Open Access
6 Citations
3,050 Views
18 Pages

Vibro-Acoustic Platelet Activation: An Additive Mechanism of Prothrombosis with Applicability to Snoring and Obstructive Sleep Apnea

  • Daniel E. Palomares,
  • Phat L. Tran,
  • Catherine Jerman,
  • Moe Momayez,
  • Pierre Deymier,
  • Jawaad Sheriff,
  • Danny Bluestein,
  • Sairam Parthasarathy and
  • Marvin J. Slepian

Introduction: Obstructive sleep apnea (OSA) and loud snoring are conditions with increased cardiovascular risk and notably an association with stroke. Central in stroke are thrombosis and thromboembolism, all related to and initiaing with platelet ac...

(This article belongs to the Special Issue Fundamentals and Applications of Fluid Mechanics and Acoustics in Biomedical Engineering)
  • Article
  • Open Access
3 Citations
2,457 Views
13 Pages

Poly(glycerol sebacate) is a biocompatible elastomer that has gained increasing attention as a potential biomaterial for tissue engineering applications. In particular, PGS is capable of providing shape memory effects and allows for a free form, whic...

(This article belongs to the Special Issue Advanced Engineering Technology in Orthopaedic Research)
  • Article
  • Open Access
6 Citations
4,910 Views
28 Pages

Tuning Fatty Acid Profile and Yield in Pichia pastoris

  • Simon Kobalter,
  • Alena Voit,
  • Myria Bekerle-Bogner,
  • Haris Rudalija,
  • Anne Haas,
  • Tamara Wriessnegger and
  • Harald Pichler

Fatty acids have been supplied for diverse non-food, industrial applications from plant oils and animal fats for many decades. Due to the massively increasing world population demanding a nutritious diet and the thrive to provide feedstocks for indus...

(This article belongs to the Section Biochemical Engineering)
  • Review
  • Open Access
38 Citations
7,966 Views
14 Pages

Investigating Immunomodulatory Biomaterials for Preventing the Foreign Body Response

  • Alexia Kim,
  • Mauricio A. Downer,
  • Charlotte E. Berry,
  • Caleb Valencia,
  • Alex Z. Fazilat and
  • Michelle Griffin

Implantable biomaterials represent the forefront of regenerative medicine, providing platforms and vessels for delivering a creative range of therapeutic benefits in diverse disease contexts. However, the chronic damage resulting from implant rejecti...

(This article belongs to the Special Issue Biomaterials and Their Application to Wound Healing and Tissue Engineering)
  • Review
  • Open Access
63 Citations
7,342 Views
21 Pages

A Systematic Review of Machine-Learning Solutions in Anaerobic Digestion

  • Harvey Rutland,
  • Jiseon You,
  • Haixia Liu,
  • Larry Bull and
  • Darren Reynolds

The use of machine learning (ML) in anaerobic digestion (AD) is growing in popularity and improves the interpretation of complex system parameters for better operation and optimisation. This systematic literature review aims to explore how ML is curr...

(This article belongs to the Section Biochemical Engineering)
  • Article
  • Open Access
11 Citations
2,851 Views
11 Pages

Influence of Lateralization and Distalization on Joint Function after Primary Reverse Total Shoulder Arthroplasty

  • Umile Giuseppe Longo,
  • Edoardo Franceschetti,
  • Arianna Carnevale,
  • Emiliano Schena,
  • Giulia Cozza,
  • Giovanni Perricone,
  • Marco Edoardo Cardinale and
  • Rocco Papalia

The purpose of this study was to investigate how lateralization shoulder angle (LSA) and distalization shoulder angle (DSA) are related to clinical and kinematic outcomes after reverse total shoulder arthroplasty. Thirty-three patients were evaluated...

(This article belongs to the Section Biomechanics and Sports Medicine)
  • Article
  • Open Access
10 Citations
2,504 Views
15 Pages

Osteogenic Effect of a Bioactive Calcium Alkali Phosphate Bone Substitute in Humans

  • Christine Knabe,
  • Doaa Adel-Khattab,
  • Mohamed Rezk,
  • Jia Cheng,
  • Georg Berger,
  • Renate Gildenhaar,
  • Janka Wilbig,
  • Jens Günster,
  • Alexander Rack and
  • Michael Stiller
  • + 2 authors

(1) Background: The desire to avoid autograft harvesting in implant dentistry has prompted an ever-increasing quest for bioceramic bone substitutes, which stimulate osteogenesis while resorbing in a timely fashion. Consequently, a highly bioactive si...

(This article belongs to the Section Biomedical Engineering and Biomaterials)
  • Review
  • Open Access
5 Citations
4,105 Views
15 Pages

The Role of Imaging of Lymphatic System to Prevent Cancer Related Lymphedema

  • Vincenzo Cuccurullo,
  • Marco Rapa,
  • Barbara Catalfamo,
  • Gianluca Gatta,
  • Graziella Di Grezia and
  • Giuseppe Lucio Cascini

Lymphedema is a progressive chronic condition affecting approximately 250 million people worldwide, a number that is currently underestimated. In Western countries, the most common form of lymphedema of the extremities is cancer-related and less radi...

(This article belongs to the Section Biosignal Processing)
  • Article
  • Open Access
6 Citations
3,746 Views
19 Pages

In this study, the surface laser treatment of a new type of dental biomaterial, a Ti-graphite composite, prepared by low-temperature powder metallurgy, was investigated. Different levels of output laser power and the scanning speed of the fiber nanos...

(This article belongs to the Section Biomedical Engineering and Biomaterials)
  • Article
  • Open Access
32 Citations
3,984 Views
16 Pages

An Improved Microaneurysm Detection Model Based on SwinIR and YOLOv8

  • Bowei Zhang,
  • Jing Li,
  • Yun Bai,
  • Qing Jiang,
  • Biao Yan and
  • Zhenhua Wang

Diabetic retinopathy (DR) is a microvascular complication of diabetes. Microaneurysms (MAs) are often observed in the retinal vessels of diabetic patients and represent one of the earliest signs of DR. Accurate and efficient detection of MAs is cruci...

(This article belongs to the Section Biosignal Processing)
  • Review
  • Open Access
13 Citations
3,842 Views
36 Pages

Simulation and Optimization: A New Direction in Supercritical Technology Based Nanomedicine

  • Yulan Huang,
  • Yating Zheng,
  • Xiaowei Lu,
  • Yang Zhao,
  • Da Zhou,
  • Yang Zhang and
  • Gang Liu

In recent years, nanomedicines prepared using supercritical technology have garnered widespread research attention due to their inherent attributes, including structural stability, high bioavailability, and commendable safety profiles. The preparatio...

(This article belongs to the Section Nanobiotechnology and Biofabrication)
  • Article
  • Open Access
2,735 Views
13 Pages

Left Ventricular Assist Device Pump Obstruction Reduces Native Heart Efficiency

  • Ricardo Montes,
  • Saniya Salim Ueckert,
  • Vi Vu and
  • Karen May-Newman

Obstruction of the LVAD flow path can occur when blood clots or tissue overgrowth form within the inflow cannula, pump body, or outflow graft, and it can lead to thrombus, embolism, and stroke. The goal of this study was to measure the impact of prog...

(This article belongs to the Special Issue Individualized Cardiovascular Implants: Latest Devices, Techniques and Strategies)
  • Article
  • Open Access
5 Citations
5,503 Views
14 Pages

Screw Stress Distribution in a Clavicle Fracture with Plate Fixation: A Finite Element Analysis

  • Angelo Alito,
  • Domenico Fenga,
  • Giada Tropeano,
  • Demetrio Milardi,
  • Danilo Leonetti,
  • Alba Migliorato,
  • Adriana Tisano,
  • Danilo D’Andrea and
  • Vincenzo Filardi

Clavicle midshaft fractures are mostly treated surgically by open internal reduction with a superior or anteroinferior plate and screws or by intramedullary nailing. Screw positioning plays a critical role in determining the stress distribution. Ther...

(This article belongs to the Special Issue Application of Computational Models in Optimizing Orthopedic Surgical Treatment)
  • Article
  • Open Access
6 Citations
6,823 Views
14 Pages

High-Accuracy Neuro-Navigation with Computer Vision for Frameless Registration and Real-Time Tracking

  • Isabella Chiurillo,
  • Raahil M. Sha,
  • Faith C. Robertson,
  • Jian Liu,
  • Jacqueline Li,
  • Hieu Le Mau,
  • Jose M. Amich,
  • William B. Gormley and
  • Roman Stolyarov

For the past three decades, neurosurgeons have utilized cranial neuro-navigation systems, bringing millimetric accuracy to operating rooms worldwide. These systems require an operating room team, anesthesia, and, most critically, cranial fixation. As...

(This article belongs to the Special Issue Machine Learning and Artificial Intelligence for Biomedical Applications)
  • Editorial
  • Open Access
22 Citations
3,347 Views
3 Pages

In recent years, we have witnessed remarkable progress in the field of regenerative medicine, in large part fuelled by developments in advanced biofabrication technologies such as three-dimensional (3D) bioprinting [...]

(This article belongs to the Section Biomedical Engineering and Biomaterials)
  • Article
  • Open Access
7 Citations
2,353 Views
14 Pages

Multimodal MRI for Estimating Her-2 Gene Expression in Endometrial Cancer

  • Xiwei Li,
  • Shifeng Tian,
  • Changjun Ma,
  • Lihua Chen,
  • Jingwen Qin,
  • Nan Wang,
  • Liangjie Lin and
  • Ailian Liu

Purpose: To assess the value of multimodal MRI, including amide proton transfer-weighted imaging (APT), diffusion kurtosis imaging (DKI), and T2 mapping sequences for estimating human epidermal growth factor receptor-2 (Her-2) expression in patients...

(This article belongs to the Special Issue Advanced Diffusion MRI and Its Clinical Applications)
  • Article
  • Open Access
6 Citations
4,628 Views
18 Pages

Training Postural Balance Control with Pelvic Force Field at the Boundary of Stability

  • Isirame Omofuma,
  • Victor Santamaria,
  • Xupeng Ai and
  • Sunil Agrawal

This study characterizes the effects of a postural training program on balance and muscle control strategies in a virtual reality (VR) environment. The Robotic Upright Stand Trainer (RobUST), which applies perturbative forces on the trunk and assisti...

(This article belongs to the Section Biomechanics and Sports Medicine)
  • Article
  • Open Access
2 Citations
2,564 Views
11 Pages

The Effect of Cerclage Banding Distally to a Clamshell Fracture Pattern in Total Hip Arthroplasty—A Biomechanical Study

  • Philipp Kastner,
  • Ivan Zderic,
  • Boyko Gueorguiev,
  • Torsten Pastor,
  • Matthias Luger,
  • Tobias Gotterbarm and
  • Clemens Schopper

Objectives: As currently there is no existing biomechanical work on the topic of interest, the aim of the current study was to investigate the effect of cerclage banding distally to an intraoperatively occurring proximal periprosthetic femoral clamsh...

(This article belongs to the Special Issue Advances in Trauma and Injury Biomechanics)
  • Communication
  • Open Access
6 Citations
3,501 Views
18 Pages

Discovery Viewer (DV): Web-Based Medical AI Model Development Platform and Deployment Hub

  • Valentin Fauveau,
  • Sean Sun,
  • Zelong Liu,
  • Xueyan Mei,
  • James Grant,
  • Mikey Sullivan,
  • Hayit Greenspan,
  • Li Feng and
  • Zahi A. Fayad

The rapid rise of artificial intelligence (AI) in medicine in the last few years highlights the importance of developing bigger and better systems for data and model sharing. However, the presence of Protected Health Information (PHI) in medical data...

(This article belongs to the Section Biosignal Processing)
  • Article
  • Open Access
2,221 Views
14 Pages

Reliability of Systematic and Targeted Biopsies versus Prostatectomy

  • Tianyuan Guan,
  • Abhinav Sidana and
  • Marepalli B. Rao

Systematic Biopsy (SBx) has been and continues to be the standard staple for detecting prostate cancer. The more expensive MRI guided biopsy (MRITBx) is a better way of detecting cancer. The prostatectomy can provide an accurate condition of the pros...

(This article belongs to the Section Biomedical Engineering and Biomaterials)
  • Review
  • Open Access
72 Citations
15,873 Views
27 Pages

fNIRS-EEG BCIs for Motor Rehabilitation: A Review

  • Jianan Chen,
  • Yunjia Xia,
  • Xinkai Zhou,
  • Ernesto Vidal Rosas,
  • Alexander Thomas,
  • Rui Loureiro,
  • Robert J. Cooper,
  • Tom Carlson and
  • Hubin Zhao

Motor impairment has a profound impact on a significant number of individuals, leading to a substantial demand for rehabilitation services. Through brain–computer interfaces (BCIs), people with severe motor disabilities could have improved comm...

(This article belongs to the Special Issue Technologies for Monitoring and Rehabilitation of Motor Disabilities)
  • Article
  • Open Access
8 Citations
3,265 Views
17 Pages

The manual segmentation of retinal layers from OCT scan images is time-consuming and costly. The deep learning approach has potential for the automatic delineation of retinal layers to significantly reduce the burden of human graders. In this study,...

(This article belongs to the Special Issue Pathophysiology and Translational Research of Retinal Diseases)
  • Article
  • Open Access
6 Citations
3,283 Views
19 Pages

Improvement of Metal-Doped β-TCP Scaffolds for Active Bone Substitutes via Ultra-Short Laser Structuring

  • Íris Soares,
  • Lamborghini Sotelo,
  • Ina Erceg,
  • Florian Jean,
  • Marie Lasgorceix,
  • Anne Leriche,
  • Maja Dutour Sikirić,
  • Katarina Marušić,
  • Silke Christiansen and
  • Albena Daskalova

Various efforts have been made to develop antibacterial biomaterials capable of also sustaining bone remodulation to be used as bone substitutes and reduce patient infection rates and related costs. In this work, beta-tricalcium phosphate (β-TCP...

(This article belongs to the Special Issue Bone Tissue Engineering and Translational Research)

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Bioengineering - ISSN 2306-5354