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Separations, Volume 12, Issue 8

2025 August - 36 articles

Cover Story: Extra virgin olive oil production generates a large quantity of phenolic-rich waste biomass in the form of olive leaves. Olive leaf extracts exhibit powerful antioxidant properties, making them a promising resource for the food industry. Despite their long history in traditional medicine, olive leaves’ potential remains untapped, partly because the content of phenolic compounds is influenced by many factors. This study investigates how the concentration of bioactive phenols in olive leaves varies according to cultivar, harvesting year, and the plant's phenological phase. In total, 25 phenolic derivatives were analyzed using HPLC-DAD-MS; the resulting data were processed with 3-way ANOVA, Genetic Algorithm with Linear Discriminant Analysis, and Random Forest, highlighting correlations between phenolic compounds and different sources of variability. View this paper
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Articles (36)

  • Article
  • Open Access
1 Citations
1,493 Views
18 Pages

The excessive emission of cadmium (Cd2+) poses a serious threat to the aquatic environment due to its high toxicity and bioaccumulation potential. This study constructed three types of vertical-subsurface-flow constructed wetlands configured with iro...

  • Article
  • Open Access
4 Citations
2,066 Views
15 Pages

The increasing presence of tetracycline antibiotics (TCs) in water sources poses significant environmental and public health risks, necessitating effective treatment technologies. This study investigates the degradation of three types of TCs in water...

(This article belongs to the Section Environmental Separations)
  • Article
  • Open Access
2 Citations
1,711 Views
12 Pages

Microwave Extraction of Antioxidant Polysaccharides from Plantago depressa and Their Effects on SOD and GSH-Px in Drosophila melanogaster Model

  • Chenqian Sun,
  • Qian Liu,
  • Xiaohua Yang,
  • Lu Li and ,
  • Yubin Wang,
  • Keran Xu and
  • Huafeng Zhang
  • + 2 authors+ 0 author

A microwave extraction method was developed to isolate antioxidant polysaccharides from Plantago depressa (psyllium), and the structure, free radical-scavenging ability, as well as in vivo antioxidant activity of psyllium polysaccharides were analyze...

(This article belongs to the Section Analysis of Food and Beverages)
  • Article
  • Open Access
3 Citations
3,170 Views
20 Pages

This study aims to compare the carbon footprints associated with the fabrication of two types of alumina-based tubular ceramic membranes used in microfiltration (MF): a multichannel membrane produced by extrusion and dip-coating, and an asymmetric ho...

(This article belongs to the Special Issue Design and Preparation of Sustainable Separation Membrane for Efficient Water Purification)
  • Review
  • Open Access
7 Citations
4,346 Views
19 Pages

Membrane separation technology can be operated in moderate conditions with low energy consumption and has been widely explored and increasingly applied in the water treatment, food, chemical, and pharmaceutical industries. As an upgraded counterpart,...

(This article belongs to the Special Issue Design and Preparation of Sustainable Separation Membrane for Efficient Water Purification)
  • Article
  • Open Access
1 Citations
1,136 Views
12 Pages

Effect of Performance and Fouling Mechanisms of Thermo-Responsive Membranes on Treating Secondary Effluent Containing Added Sulfamethoxazole

  • Lian Yang,
  • Haoran Qiu,
  • Yingjie Yang,
  • Lijun Zhao and ,
  • Ping Xiao,
  • Guoliang Liu,
  • Jiang Chang,
  • Shaoxia Yang and
  • Feng Xiao
  • + 4 authors+ 0 author

Wastewater treatment plants generally lack a specialized design for the efficient removal of sulfamethoxazole (SMX), a toxic and bio-resistant compound. In this study, secondary effluent from a Beijing wastewater reclamation treatment plant was spike...

(This article belongs to the Special Issue Application of Adsorption and Separation Technologies in Water Treatment)
  • Article
  • Open Access
2 Citations
2,394 Views
28 Pages

Coriander (Coriandrum sativum L.) has significant value in the food industry due to its unique flavor and health benefits. However, its polyphenol content and antioxidant activity have not been systematically analyzed during storage. This study optim...

  • Article
  • Open Access
1 Citations
2,547 Views
11 Pages

Phytochemical and Nutritional Profile of Apricot, Plum-Apricot, and Plum Stones

  • Dasha Mihaylova,
  • Galia Gentscheva,
  • Nadezhda Petkova-Ognyanova,
  • Anton Slavov and
  • Aneta Popova

Fruit stones constitute a significant portion of solid waste generated from the consumption and processing of fruits. This study demonstrated the potential of fruit stones as viable sources of nutritional compounds. The stones from three types of fru...

(This article belongs to the Section Analysis of Natural Products and Pharmaceuticals)
  • Article
  • Open Access
3 Citations
2,918 Views
13 Pages

Due to the nearly identical chemical properties of Lu and Yb, the production of no-carrier-added (NCA) 177Lu faces significant challenges in their separation. Achieving efficient and streamlined separation of Lu and Yb is crucial for the production o...

  • Article
  • Open Access
14 Citations
5,467 Views
34 Pages

Hydrophobic Natural Deep Eutectic Solvents for Extraction of Bioactive Compounds: Multiscale Characterization, Quantum Simulations, and Molecular Interaction Studies with Cry j 1 and Amb a 1 Allergens

  • Tochukwu Oluwatosin Maduka,
  • Qingyue Wang,
  • Miho Suzuki,
  • Christian Ebere Enyoh and ,
  • Weiqian Wang and
  • Md. Sohel Rana
  • + 1 author+ 0 author

This study explores the synthesis, characterization, and extraction efficiency of hydrophobic natural deep eutectic solvents (NADESs), along with the allergen-modulating potential of extracted bioactive compounds. Six NADESs were synthesized using bi...

(This article belongs to the Special Issue Green Extraction of Natural Products for Application in Pharmaceuticals, Foods, Cosmetics and Agriculture)
  • Article
  • Open Access
3,296 Views
19 Pages

Ultrafiltration strips water of bacteria. The common misconception is that the filtrate is thus free of bacteria. This only applies, however, in the case that the filtrate compartment is sterile. In real-world applications, the filtrate is rapidly re...

(This article belongs to the Section Environmental Separations)
  • Article
  • Open Access
1 Citations
3,258 Views
24 Pages

The copper oxide ore in Zambia exhibits complex mineralogical characteristics, with copper primarily occurring in mica. The local hydrometallurgical plant employs heating–agitation acid leaching, which is hindered by a low leaching rate and pro...

(This article belongs to the Section Environmental Separations)
  • Article
  • Open Access
2 Citations
2,012 Views
14 Pages

Base Mine Lake (BML) is the first full-scale demonstration of water-capped tailing technology in a pit lake to reclaim lands impacted by surface mining in the Alberta Oil Sands Region (AOSR). Biogeochemical cycling and/or exchange near the fluid wate...

(This article belongs to the Section Forensic Science and Toxicology)
  • Article
  • Open Access
1,971 Views
12 Pages

The acquisition of high-purity impurities is pivotal for structural identification and an origin analysis, thereby laying a critical foundation for subsequent toxicological evaluation, quality standard development, and process optimization. This stud...

(This article belongs to the Section Chromatographic Separations)
  • Article
  • Open Access
5 Citations
4,602 Views
22 Pages

Valorization of the Bioactive Potential of Juniperus communis L. Berry Extracts Using a Box–Behnken Design and Characterization of Kernel Oil Compounds

  • Theofania Tsitsirigka,
  • Dimitrios Kalompatsios,
  • Vassilis Athanasiadis,
  • Eleni Bozinou and ,
  • Athanassios I. Sfougaris and
  • Stavros I. Lalas
  • + 1 author+ 0 author

This study presents a comprehensive valorization of Juniperus communis L., a plant known for its culinary and therapeutic applications. Juniper berries are rich in antioxidant compounds such as polyphenols and ascorbic acid, while their kernels conta...

(This article belongs to the Special Issue Advances in the Analysis of Bioactive Plant Extracts: Separation Techniques and Their Applications)
  • Article
  • Open Access
2,258 Views
10 Pages

Molluscicidal Activity of the Crude Extract and Fractions of Myrsine parvifolia

  • Keyla Nunes Farias Gomes,
  • Leonardo da Silva Rangel,
  • João Claudio Vitoria Ático Leite,
  • Gabriel Rocha Caldas and ,
  • Arthur Luiz Corrêa,
  • Marcelo Guerra Santos,
  • Leandro Machado Rocha,
  • José Augusto Albuquerque dos Santos and
  • Robson Xavier Faria
  • + 4 authors+ 0 author

As the second most common infectious parasitic disease in the world, schistosomiasis is present in Brazil, mainly in the Northeast and Southeast regions. Currently, the recommended form of prevention is controlling this disease’s intermediate h...

(This article belongs to the Special Issue Advanced Research on Extraction and Analysis of Plant Extracts)
  • Article
  • Open Access
9 Citations
4,762 Views
18 Pages

Ion-exchange membranes (IEMs) are widely used in reverse-electrodialysis (RED) technology, which can collect the salinity gradient energy between concentrated and diluted solutions and convert it into electromotive force (EMF) to drive power generati...

(This article belongs to the Section Purification Technology)
  • Article
  • Open Access
4 Citations
1,824 Views
21 Pages

Experimental and Quantum Mechanical Studies of Efficient Re(VII)/Mo(VI) Separation by a Magnetic Amino-Functionalized Polymer

  • Bojana Marković,
  • Goran Janjić,
  • Antonije Onjia,
  • Tamara Tadić and ,
  • Plamen Stefanov and
  • Aleksandra Nastasović
  • + 1 author+ 0 author

A previously synthesized and functionalized magnetic glycidyl methacrylate-based nanocomposite, mPGMT-deta, was tested as a sorbent for Re(VII) oxoanions in Mo(VI)-containing solutions. The effect of pH on the removal efficiency and the separation fa...

(This article belongs to the Section Materials in Separation Science)
  • Article
  • Open Access
5 Citations
3,466 Views
18 Pages

Preparation of EDTA-2Na-Fe3O4-Activated Carbon Composite and Its Adsorption Performance for Typical Heavy Metals

  • Yannan Lv,
  • Shenrui Han,
  • Wenqing Wen,
  • Xinzhu Bai and ,
  • Qiao Sun,
  • Li Chen,
  • Haonan Zhang,
  • Fansong Mu and
  • Meng Luo
  • + 4 authors+ 0 author

This study developed a new magnetic adsorbent from waste coconut shells using high-temperature carbonization, EDTA-2Na chelation, and Fe3O4 magnetic loading. Response surface methodology optimized the preparation conditions to a mass ratio of activat...

(This article belongs to the Special Issue Application of Advanced Materials and Technologies in the Separation and Adsorption)
  • Article
  • Open Access
1 Citations
3,690 Views
20 Pages

Chromatographic and Chemometric Characterization of the Two Wild Edible Mushrooms Fistulina hepatica and Clitocybe nuda: Insights into Nutritional, Phenolic, and Antioxidant Profiles

  • Ana Saldanha,
  • Mikel Añibarro-Ortega,
  • Adriana K. Molina,
  • José Pinela and ,
  • Maria Inês Dias and
  • Carla Pereira
  • + 1 author+ 0 author

Fistulina hepatica (Schaeff.) With. and Clitocybe nuda (Bull.) H.E. Bigelow & A.H. Sm. are wild edible mushrooms with nutritional and functional potential that remain insufficiently characterized. This study provides the first comparative assessm...

(This article belongs to the Special Issue Advanced Separation Methods for Safety Assessment and Valorization of By-Products)
  • Review
  • Open Access
8 Citations
4,767 Views
23 Pages

Flocculants are indispensable in water and wastewater treatment, enabling the aggregation and removal of suspended particles, colloids, and emulsions. However, the conventional development and application of flocculants rely heavily on empirical meth...

(This article belongs to the Section Environmental Separations)
  • Article
  • Open Access
2 Citations
2,315 Views
17 Pages

Inverse Punicines: Isomers of Punicine and Their Application in LiAlO2, Melilite and CaSiO3 Separation

  • Maximilian H. Fischer,
  • Ali Zgheib,
  • Iliass El Hraoui,
  • Alena Schnickmann and ,
  • Thomas Schirmer,
  • Gunnar Jeschke and
  • Andreas Schmidt
  • + 2 authors+ 0 author

The transition to sustainable energy systems demands efficient recycling methods for critical raw materials like lithium. In this study, we present a new class of pH- and light-switchable flotation collectors based on isomeric derivatives of the natu...

(This article belongs to the Special Issue Application of Green Flotation Technology in Mineral Processing)
  • Article
  • Open Access
3,212 Views
17 Pages

Cuscohygrine and Hygrine as Biomarkers for Coca Leaf Chewing: Analytical Challenges in GC-MS Detection and Implications for the Differentiation of Cocaine Use in Forensic Toxicology

  • Nélida C. Rubio,
  • Iván Alvarez-Freire,
  • Pamela Cabarcos-Fernández,
  • María J. Tabernero-Duque and ,
  • Inés Sánchez-Sellero,
  • Antonio Moreda-Piñeiro,
  • Pilar Bermejo-Barrera and
  • Ana M. Bermejo-Barrera
  • + 3 authors+ 0 author

Cuscohygrine (CUS) and hygrine (HYG) are pyrrolidine alkaloids proposed as biomarkers of coca leaf consumption, a culturally accepted practice in some Latin American countries. Differentiating legal coca use from illicit cocaine consumption holds for...

  • Article
  • Open Access
1 Citations
1,747 Views
11 Pages

Directed Message-Passing Neural Networks for Gas Chromatography

  • Daniel Struk,
  • Rizky Ilhamsyah,
  • Jean-Marie D. Dimandja and
  • Peter J. Hesketh

In this paper, the directed message-passing neural network architecture is used to predict several quantities of interest in gas chromatography: retention times, Clarke-Glew 3-point thermodynamic parameters for simulation, and retention indices. The...

(This article belongs to the Special Issue State of the Art and Challenges in the Analysis of Volatile Organic Compounds)
  • Article
  • Open Access
2 Citations
2,450 Views
17 Pages

Magnetic nanoparticles (MNPs), especially iron oxide (Fe3O4), display distinctive superparamagnetic characteristics and elevated surface-area-to-volume ratios, facilitating improved physicochemical interactions with solutes and pollutants. These char...

(This article belongs to the Section Purification Technology)
  • Article
  • Open Access
2 Citations
2,469 Views
14 Pages

Carbon Dioxide Absorption by Polyethylene Glycol Dimethyl Ether Modified by 2-methylimidazole

  • Yan Wu,
  • Zicheng Wang,
  • Hui Yu,
  • Bin Ding and ,
  • Ke Fei,
  • Xueli Ma,
  • Baoshen Xu,
  • Yonghu Zhang,
  • Xiaoning Fu and
  • Nan Li
  • + 6 authors+ 1 author

Developing and utilizing capture and storage technologies for CO2 has become a critical research topic due to the significant greenhouse effect caused by excessive CO2 emissions. A conventional physical absorption process for CO2 capture is polyethyl...

(This article belongs to the Section Separation Engineering)
  • Article
  • Open Access
2 Citations
2,544 Views
19 Pages

Efficient Extraction of 1,2-Dichloroethane from Wastewater Using Hydrophobic Deep Eutectic Solvents: A Green Approach

  • Irfan Wazeer,
  • Abdullah Omair,
  • Lahssen El Blidi,
  • Salim Mokraoui and ,
  • Emad Ali and
  • Mohamed K. Hadj-Kali
  • + 1 author+ 0 author

This study provides a thorough examination of the utilization of hydrophobic deep eutectic solvents (HDESs) for the extraction of 1,2-dichloroethane (1,2-DCA) from effluent, with an emphasis on a sustainable and environmentally friendly approach. The...

(This article belongs to the Special Issue Green Separation and Purification Technology)
  • Article
  • Open Access
2 Citations
4,694 Views
27 Pages

Separating 2-Propanol and Water: A Comparative Study of Extractive Distillation, Salting-Out, and Extraction

  • Aleksandra Sander,
  • Marko Rogošić,
  • Leonarda Frljak,
  • Daniela Vasiljević and ,
  • Iva Blažević and
  • Jelena Parlov Vuković
  • + 1 author+ 0 author

Separating azeotropes is an important, difficult, and expensive task, in particular for the 2-propanol–water mixture. The literature on the problem is rich in modeling studies but often lacking even the simplest experimental confirmation. In th...

  • Article
  • Open Access
8 Citations
2,742 Views
23 Pages

Aimed at developing an economical and efficient biosorbent for the adsorption and separation of rare earth ions, this study employed Spirulina dry powder biomass as a biosorbent to investigate its removal performance for Pr3+ in aqueous solutions. Ex...

  • Article
  • Open Access
7 Citations
2,997 Views
14 Pages

Pilot-Scale Phycocyanin Extraction by the Green Two-Step Ultrasound-Based UltraBlu Process

  • Rosaria Lauceri,
  • Melissa Pignataro,
  • Antonio Giorgi,
  • Antonio Idà and
  • Lyudmila Kamburska

Phycocyanin is a natural, non-toxic, blue pigment-protein with many commercial applications. Its exploitation in various biotechnological sectors strongly depends on its purity grade (P). Phycocyanin is largely used in food industry where a low purit...

(This article belongs to the Special Issue Application of Sustainable Separation Techniques in Food Processing)
  • Article
  • Open Access
3 Citations
2,553 Views
14 Pages

Interfacial solar evaporation has emerged as a promising strategy for freshwater production, where 3D evaporators offer distinct advantages in heat management and salt rejection. Freeze–thaw cycling is a widely adopted fabrication method for 3D...

(This article belongs to the Collection Feature Paper Collection in Section 'Materials in Separation Science')
  • Article
  • Open Access
11 Citations
2,648 Views
21 Pages

Seasonal and Cultivar-Dependent Phenolic Dynamics in Tuscan Olive Leaves: A Two-Year Study by HPLC-DAD-MS for Food By-Product Valorization

  • Tommaso Ugolini,
  • Lorenzo Cecchi,
  • Graziano Sani,
  • Irene Digiglio and ,
  • Barbara Adinolfi,
  • Leonardo Ciaccheri,
  • Bruno Zanoni,
  • Fabrizio Melani and
  • Nadia Mulinacci
  • + 4 authors+ 0 author

Olive tree leaf is a phenol-rich, high-potential-value biomass that can be used to formulate food additives and supplements. Leaf phenolic content varies depending on numerous factors, like cultivar, geographical origin, year, and season of harvest....

  • Article
  • Open Access
6 Citations
2,267 Views
11 Pages

Flotation Behaviours of Ilmenite and Associated Solution Chemistry Properties Using Saturated Fatty Acids as the Collector

  • Jihua Zhai,
  • Hao He,
  • Pan Chen,
  • Lin Song and ,
  • Xiaohai Yao and
  • Hongxian Zhang
  • + 1 author+ 0 author

A series of homologous saturated fatty acids were introduced and evaluated as collectors for ilmenite flotation using a combination of micro-flotation tests and surface tension measurements. The results showed that ilmenite exhibited good flotation b...

(This article belongs to the Section Separation Engineering)
  • Article
  • Open Access
2 Citations
2,332 Views
15 Pages

Adsorption Performance and Mechanism of Gallium from Sulfuric Acid Leach Liquor of High-Alumina Fly Ash

  • Wenfen Wu,
  • Chaolu Wen,
  • Shaopeng Li,
  • Zhenhua Sun and ,
  • Xinjuan Hou,
  • Huiquan Li and
  • Zhibin Ma
  • + 2 authors+ 0 author

High-alumina fly ash may potentially be a valuable source of Ga with a concentration of Ga at 80 mg/kg. Direct adsorption and enrichment of Ga from sulfuric acid leach liquor of high-alumina fly ash is developed in this study. The H-type chelating re...

(This article belongs to the Section Environmental Separations)
  • Article
  • Open Access
45 Citations
4,815 Views
25 Pages

The discharge of synthetic dyes in industrial wastewaters poses a serious environmental threat as they are difficult to degrade naturally and are harmful to aquatic organisms. This study aimed to evaluate the feasibility of using clean untreated rice...

(This article belongs to the Section Environmental Separations)
  • Article
  • Open Access
2 Citations
2,468 Views
14 Pages

Tomatoes are globally esteemed not only for their nutritional value but also for their complex and appealing aroma, a key determinant of consumer preference. The present study aimed to comprehensively characterise the volatilomic fingerprints of thre...

(This article belongs to the Section Analysis of Food and Beverages)
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Separations - ISSN 2297-8739