Advances in the Analysis of Bioactive Plant Extracts: Separation Techniques and Their Applications

A special issue of Separations (ISSN 2297-8739). This special issue belongs to the section "Analysis of Natural Products and Pharmaceuticals".

Deadline for manuscript submissions: 10 January 2026 | Viewed by 48

Special Issue Editors


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Guest Editor
Faculty of Technology, Department of Food Technology and Biotechnology, University of Nis, Leskovac, Serbia
Interests: food analysis; phytochemistry; enzyme; biotechnology; LC-MS/MS; antioxidant activity

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Guest Editor
Faculty of Technology, Department of Organic and Technological Sciences, University of Nis, Leskovac, Serbia
Interests: chemistry of natural organic compounds; chemical kinetics; ICP-OES; photochemistry; dietary supplements; nanomaterials

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Guest Editor
Faculty of Technology and Metallurgy, University of Belgrade, 11000 Belgrade, Serbia
Interests: enzyme reaction engineering; biocatalysis; biotransformation; design and optimization of enzyme transformations of natural compounds; modeling of bioprocesses; plant proteins; bioactive peptides; enzymatic-assisted extraction; intensification of bioactive compound extraction; immobilized enzymes; encapsulation of bioactive compounds
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Special Issue Information

Dear Colleagues,

Natural products remain an abundant source of structurally diverse and biologically active compounds with potential pharmaceutical applications. With the continuous advancement of analytical methodologies, the quantification, identification, and characterization of constituents derived from natural sources have become more accurate and efficient. This Special Issue aims to gather original research and review articles focusing on the latest analytical approaches applied to natural products and pharmaceuticals, including innovative chromatographic and spectroscopic techniques and hyphenated methods (e.g., LC-MS, GC-MS, NMR). Emphasis will also be placed on the standardization, quality control, stability, and bioavailability of plant-derived compounds, as well as the challenges and solutions in metabolite profiling and analytical validation. We warmly invite contributions from scientists working across the fields of pharmaceutical analysis, natural product chemistry, and bioactive compound research.

Dr. Saša Savić
Dr. Sanja Petrovic
Prof. Dr. Zorica Knežević-Jugović
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Separations is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • natural products
  • pharmaceutical analysis
  • bioactive compounds
  • chromatographic techniques
  • spectroscopic methods
  • LC-MS/ICP-OES/GC-MS/NMR
  • metabolite profiling
  • stability testing and quality control

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Published Papers

This special issue is now open for submission.
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