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Processes, Volume 8, Issue 4

April 2020 - 119 articles

Cover Story: Amyloid beta peptide (Aβ)-related studies require an adequate supply of purified Aβ. Aβs are “difficult sequences” to synthesize chemically, and low yields are common due to aggregation during purification. Here, we demonstrate an easier synthesis, deprotection, reduction, cleavage, and purification process for Aβ(1-40) using standard Fmoc-protected amino acids and SPPS resin (HMBA resin) that provide higher yields of Aβ(1-40) than previous standard protocols. The method described herein is not limited to the production of Aβ(1-40) and can be used to synthesize other easily-oxidized and aggregating sequences. Our proposed methodology will contribute to various fields using “difficult sequence” peptides. View this paper.
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Articles (119)

  • Article
  • Open Access
7 Citations
3,838 Views
9 Pages

24 April 2020

Tissue adhesives have been widely used in surgical procedures. Compared to traditional surgical sutures, tissue adhesives provide fast bonding experiences and full closure of wounds. However, current tissue adhesives are mostly fossil-based synthetic...

  • Article
  • Open Access
16 Citations
5,527 Views
15 Pages

Enhancing Astaxanthin Biosynthesis by Rhodosporidium toruloides Mutants and Optimization of Medium Compositions Using Response Surface Methodology

  • Tuyet Nhung Tran,
  • Dai-Hung Ngo,
  • Quoc Tuan Tran,
  • Hoang Chinh Nguyen,
  • Chia-Hung Su and
  • Dai-Nghiep Ngo

24 April 2020

Astaxanthin is a valuable carotenoid, which has been approved as a food coloring by the US Food and Drug Administration and is considered as a food dye by the European Union (European Commission). This work aimed to attain Rhodosporidium toruloides m...

  • Article
  • Open Access
6 Citations
4,279 Views
15 Pages

23 April 2020

Over the past two decades, the alkaline persulfate oxidation (PO) with thermal and/or ultraviolet (UV) assisted digestion method has been widely used for digestion of nitrogen containing compounds (N-compounds) in water quality routine analysis in la...

  • Article
  • Open Access
20 Citations
6,525 Views
27 Pages

Optimisation and Modelling of Anaerobic Digestion of Whiskey Distillery/Brewery Wastes after Combined Chemical and Mechanical Pre-Treatment

  • Burcu Gunes,
  • Maxime Carrié,
  • Khaled Benyounis,
  • Joseph Stokes,
  • Paul Davis,
  • Cathal Connolly and
  • Jenny Lawler

23 April 2020

Whiskey distillery waste streams consisting of pot ale (liquid residue) and spent grain (solid residue) are high strength organic wastes and suitable feedstock for anaerobic digestion (AD) from both economic and environmental stand points. Anaerobic...

  • Article
  • Open Access
23 Citations
4,294 Views
14 Pages

23 April 2020

Bone has a complex hierarchical structure with the capability of self-regeneration. In the case of critical-sized defects, the regeneration capabilities of normal bones are severely impaired, thus causing non-union healing of bones. Therefore, bone t...

  • Editorial
  • Open Access
2,459 Views
3 Pages

23 April 2020

Microwave heating has been widely used in the chemical industry because of its advantages, such as fast heating rate, selective and controllable heating, increasing reaction rate and reducing by-products in chemical reactions. The Special Issue conta...

  • Article
  • Open Access
23 Citations
5,103 Views
11 Pages

The Integration of Collaborative Robot Systems and Their Environmental Impacts

  • Lucian Stefanita Grigore,
  • Iustin Priescu,
  • Daniela Joita and
  • Ionica Oncioiu

23 April 2020

Today, industrial robots are used in dangerous environments in all sectors, including the sustainable energy sector. Sensors and processors collect and transmit information and data from users as a result of the application of robot control systems a...

  • Article
  • Open Access
5 Citations
4,360 Views
24 Pages

23 April 2020

Cost reduction is a cornerstone of the Lean administration’s sustainability through modify its algorithms scheme to become multi-useful. This paper focuses on control “movement” waste, to minimize pipeline, cabling and sewerage netw...

  • Feature Paper
  • Article
  • Open Access
15 Citations
8,885 Views
17 Pages

22 April 2020

Computational methods have become reliable tools in many disciplines for research and industrial design. There are, however, an ever-increasing number of details waiting to be included in the models and software, including, e.g., chemical reactions a...

  • Article
  • Open Access
23 Citations
6,832 Views
16 Pages

Holographic Imaging of Insect Cell Cultures: Online Non-Invasive Monitoring of Adeno-Associated Virus Production and Cell Concentration

  • Daniel A. M. Pais,
  • Paulo R. S. Galrão,
  • Anastasiya Kryzhanska,
  • Jérémie Barbau,
  • Inês A. Isidro and
  • Paula M. Alves

22 April 2020

The insect cell-baculovirus vector system has become one of the favorite platforms for the expression of viral vectors for vaccination and gene therapy purposes. As it is a lytic system, it is essential to balance maximum recombinant product expressi...

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Processes - ISSN 2227-9717