Biofabrication Scaffold in Regenerative Medicine

Dear Colleagues,

The emergence of biofabrication technology and its related novel concepts such as 3D and 4D bioprinting has allowed us to fabricate and mimic complex native tissues. Numerous studies have since been reported attempting to recreate native tissues by searching for the best printing parameters and conditions. The parameters vary vastly from the suitability of the biomaterials, scaffold geometry, physical and biological stimulations, and the application of biochemical and biological cues, to searching for the optimal printing conditions. The goal of such tissue engineering is to fabricate complex tissue-like structures for tissue regeneration and personalized treatments such as drug screening and toxicological studies. Of the many parameters involved in bioprinting, the biomaterial plays a huge role in determining the feasibility of constructs for tissue engineering. Biomaterial biocompatibility allows for high cell viability and high retention of growth factors whilst the structural stability and geometry of the printed constructs allows specific cellular proliferation and differentiation. Many studies have attempted to explore suitable biomaterials for various applications by modifying and tuning the characteristics of various biomaterials. Therefore, this Issue is mainly focused on the various novel modifications of biomaterials used for tissue engineering and it is hoped that such a collection of articles could be used as a platform for future brainstorming. 

Dr. Ming-You Shie
Dr. Kan Wang
Guest Editors

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