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Chemosensors, Volume 14, Issue 7

2026 July - 25 articles

Cover Story: This manuscript summarizes 25 years of transformative ORNL research (2000–2025) on environmental and biological matrices, showing how elemental detection revealed key natural processes in plants and ecosystems. Major advances include real-time aerosol analysis with LIBS to detect hazardous air pollutants, soil carbon measurement to assess sequestration and land health, and LIBS-based wood analysis to distinguish species, growth environments, and drought effects. The work also linked leaf elemental variation to biomass production, nutrient cycling, and toxic element transfer. More recently, ionomics connected elements to specific genes in plants and fungi, opening new paths in functional biology. View this paper
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Articles (25)

  • Article
  • Open Access
947 Views
13 Pages

Preventing Drug-Facilitated Sexual Assault: A Smartphone-Readout Lateral Flow Assay for GBL Detection in Water and Saliva

  • Jordi Roig-Rubio,
  • Carmen Coll,
  • Salvador Gil,
  • Pau Arroyo and ,
  • José A. Sáez and
  • Pablo Gaviña
  • + 1 author+ 0 author

The rising prevalence of Drug-Facilitated Sexual Assault (DFSA) underscores the urgent need for rapid, sensitive, and selective analytical tools. Among the most concerning substances are γ-hydroxybutyric acid (GHB) and its precursor γ-but...

(This article belongs to the Section Applied Chemical Sensors)
  • Article
  • Open Access
389 Views
14 Pages

As a core component of vitamin B12, Co2+ is closely associated with the health, life performance, and productivity of ruminants. Therefore, the selective and sensitive detection of Co2+ is of great significance. In this work, using the Au–S bon...

(This article belongs to the Special Issue Fluorescent Probes for Highly Sensitive Ion and Compound Detection)
  • Article
  • Open Access
849 Views
16 Pages

Geographical and Seasonal Differentiation Along with Quality Evaluation of Lavender Essential Oil Through Volatile Profiling

  • Cornelia Veronica Floare-Avram,
  • Olivian Marincas,
  • Dana Alina Magdas and
  • Ioana Feher

The study aimed to characterize Romanian lavender essential oils (LEOs) according to geographical regions and harvested years by combining gas chromatography–mass spectrometry (GC/MS) with chemometric analysis and quality evaluation. Sixty-four...

(This article belongs to the Special Issue Advanced Chemometric Methods for Analytical Applications)
  • Article
  • Open Access
1,051 Views
18 Pages

Hydrogen is a clean energy carrier essential for carbon neutrality, but its invisible and odorless nature poses significant safety risks, particularly during low-concentration leaks. Although metal oxide semiconductor (MOS) sensors offer fast respons...

(This article belongs to the Section Materials for Chemical Sensing)
  • Editorial
  • Open Access
790 Views
4 Pages

Chemosensors for diverse analytes have become a significant research topic experiencing innovative real-time development [...]

(This article belongs to the Special Issue Colorimetric and Fluorescent Sensors: Current Status and Future Development)
  • Review
  • Open Access
1 Citations
925 Views
36 Pages

Reperfusion after acute ischemic stroke (AIS) triggers a series of ferroptosis-related molecular events, including iron dyshomeostasis, oxidative/nitrative stress, antioxidant depletion, and membrane lipid peroxidation. Conventional ferroptosis assay...

(This article belongs to the Special Issue Advanced Optical Imaging Technologies and Fluorescent Probes)
  • Review
  • Open Access
1 Citations
944 Views
23 Pages

Functional Materials for Molecular POCT in Infectious Disease Detection: Advances and Regulatory Perspectives

  • Yan Tan,
  • Haonan Wu,
  • Junjun Lan,
  • Ting Qian and ,
  • Xin Zhou,
  • Shiyang Zhao and
  • Hui Wang
  • + 2 authors+ 0 author

On-site nucleic acid analysis for infectious diseases can be rapidly achieved through molecular point-of-care testing (molecular POCT), which plays an indispensable role in early pathogen identification, timely clinical intervention, and public healt...

(This article belongs to the Special Issue Rapid Point-of-Care Testing Technology and Application (Second Edition))
  • Article
  • Open Access
1,979 Views
14 Pages

COC Chip-Integrated Zinc Finger Protein Array for PCR-Free Detection of RASSF1A Promoter Methylation

  • Hye Yeon Jang,
  • Sthitodhi Ghosh,
  • Chong H. Ahn,
  • Narendhar Chandrasekar and ,
  • Michael Taeyoung Hwang and
  • Moon-Soo Kim
  • + 1 author+ 0 author

The detection of RASSF1A (Ras-associated domain family 1 isoform A) promoter methylation in body fluids can offer a powerful tool for the early diagnosis of bladder cancer. Zinc finger proteins (ZFPs) serve as sequence-specific recognition elements f...

(This article belongs to the Section (Bio)chemical Sensing)
  • Article
  • Open Access
430 Views
15 Pages

SDRMixer: A Lightweight Dynamic Response Mixer for Deployable Mixed-Gas Quantification Using Sensor Arrays

  • Jiahao Zhang,
  • Zaihua Duan,
  • Yuanming Wu,
  • Zhen Yuan and ,
  • Yadong Jiang and
  • Huiling Tai
  • + 1 author+ 0 author

Low-cost gas sensor arrays are attractive for mixed-gas monitoring, but deployment-oriented modeling remains challenging because mixed-gas responses are nonlinear, cross-sensitive, and strongly dependent on sensor dynamic states. Existing electronic-...

(This article belongs to the Special Issue Functional Nanomaterial-Based Gas Sensors and Humidity Sensors, 2nd Edition)
  • Article
  • Open Access
416 Views
19 Pages

The dried rhizome of Atractylodes lancea (RAL) is a widely used traditional Chinese medicine (TCM). Its quality evaluation and origin authentication have long relied on time-consuming chromatographic methods, which are poorly suited for rapid, on-sit...

(This article belongs to the Section Applied Chemical Sensors)
  • Review
  • Open Access
1,206 Views
34 Pages

Functional 2D Nanomaterials Gas Sensor for Exhaled Breath Analysis: A Review

  • Yuqing Zhang,
  • Yanjie Wang,
  • Kun Zhu,
  • Zhiqiang Lan and ,
  • Jie Wang,
  • Jian He,
  • Xiujian Chou and
  • Yong Zhou
  • + 3 authors+ 0 author

Exhaled breath analysis has emerged as a promising non-invasive approach for disease diagnosis, leveraging gas sensors for their high sensitivity, portability, and real-time monitoring capabilities. Two-dimensional nanomaterials, such as graphene, tr...

(This article belongs to the Special Issue Functional Nanomaterial-Based Gas Sensors and Humidity Sensors, 2nd Edition)
  • Article
  • Open Access
1,300 Views
23 Pages

E-Nose Classification of Muscles in Dry-Cured Bísaro Ham Using Piercing-Assisted Volatile Extraction

  • Lia Vasconcelos,
  • Javier Mateo,
  • Nuno A. S. Dias,
  • Ana Leite and ,
  • Alfredo Teixeira,
  • Sandra S. Q. Rodrigues and
  • Luís G. Dias
  • + 2 authors+ 0 author

This study evaluated the use of an E-nose using a piercing-assisted volatile extraction as a practical and non-destructive tool for distinguishing between three muscle types (biceps femoris—BF; semitendinosus—ST; and semimebranosus—...

(This article belongs to the Topic Advances in Analysis of Food and Beverages, 2nd Edition)
  • Review
  • Open Access
1 Citations
1,162 Views
20 Pages

Sodium Alginate-Based Hydrogels: Sensing and Indicating for Intelligent Food Packaging

  • Fengchao Zhou,
  • Liyan Xie,
  • Guorong Lin,
  • Yilin Lin and ,
  • Jiandong Shen,
  • Shibin Deng and
  • Gaowa Xing
  • + 2 authors+ 0 author

Intelligent food packaging (IFP) is among the key technologies for overcoming global challenges of food safety and food resource waste. Its core lies in monitoring the quality of food in real-time without damage. Sodium alginate (SA), a natural polys...

(This article belongs to the Section Materials for Chemical Sensing)
  • Article
  • Open Access
569 Views
15 Pages

A Novel Ratiometric Fluorescent Nanosensor Based on N-CDs@UiO-66-NH2 for Sensitive and Selective Detection of Nitrite

  • Tong Xiang,
  • Chongyang Zhang,
  • Qiongqiong Ren,
  • Jinlong Chang and ,
  • Linyan Xie and
  • Xuming Sun
  • + 1 author+ 0 author

Nitrite (NO2−) is a crucial environmental and food safety indicator, and excessive intake poses severe threats to human health; thus, highly sensitive and selective detection methods are urgently needed. Herein, a ratiometric fluorescent nanose...

(This article belongs to the Special Issue Advancements of Chemosensors and Biosensors in China—3rd Edition)
  • Review
  • Open Access
1 Citations
1,229 Views
34 Pages

Chemoresistive Metal Oxide-Based Sensors Synthesized Through Physical Vapor Deposition Techniques for Gas Detection

  • Andrei-Silviu Zancu,
  • Mihai Robert Zamfir,
  • Nicolae Cristian Mihailescu,
  • Constantin Pintilie and
  • Nicu Doinel Scărișoreanu

In our day-to-day lives, we are regularly exposed to a wide spectrum of dangerous gases. Their origins vary, ranging from industrial activities to objects found within our very homes. Naturally, there is an interest in developing cost-efficient and d...

(This article belongs to the Section Materials for Chemical Sensing)
  • Article
  • Open Access
1 Citations
830 Views
21 Pages

In this study, an integrated machine learning (ML)-based calibration approach was employed for the data-driven calibration of a low-cost PM2.5 sensor. The primary objective was to systematically evaluate the relative contributions of location-specifi...

(This article belongs to the Section Analytical Methods, Instrumentation and Miniaturization)
  • Review
  • Open Access
1,074 Views
47 Pages

Single-entity electrochemistry (SEE) expands the scope of analytical electrochemical measurement by shifting attention from ensemble-averaged currents to individually resolved stochastic events. This review evaluates progress toward two analytical en...

(This article belongs to the Special Issue Electrochemical Sensors and Biosensors: Recent Progress, Challenges, and Future Perspectives)
  • Article
  • Open Access
1 Citations
408 Views
17 Pages

Rapid Geographical Origin Discrimination of Tremella fusiform Based on Temporal Response Features of Electronic Nose

  • Ying Li,
  • Meng Liu,
  • Zhaomin Sun,
  • Lei Yu and ,
  • Feifei Gong and
  • Guangyu Yan
  • + 1 author+ 0 author

Rapid geographical origin discrimination of Tremella fuciformis is important for quality control and authenticity assessment; however, conventional analytical methods are often time-consuming and require complex sample preparation. In this study, a r...

(This article belongs to the Section Applied Chemical Sensors)
  • Article
  • Open Access
569 Views
15 Pages

Short-wave near-infrared (SW-NIR) spectroscopy provides a rapid and nondestructive sensing route for monitoring bread staling, but formulation-dependent moisture redistribution and starch retrogradation can make pooled spectral regression unstable. T...

(This article belongs to the Special Issue Spectroscopy, Imaging and Chemometric Modelling for Quality Analysis in Food and Drug Research)
  • Article
  • Open Access
973 Views
21 Pages

Rational Design of a Hydrophobic Ion-Pair Sensor for Potentiometric Determination of Cationic Surfactants in Disinfectants: Combined Experimental and DFT Study

  • Marija Kraševac Sakač,
  • Maksym Fizer,
  • Hanna Zhukouskaya,
  • Martin Hrubý and ,
  • Jiří Pánek,
  • Jasmin Suljagić,
  • Dean Marković,
  • Domagoj Drenjančević,
  • Nikola Sakač and
  • Marija Jozanović
  • + 6 authors+ 1 author

Cationic surfactants are widely used in disinfectants, creating a need for rapid and reliable analytical methods for their determination in complex formulations. In this study, a new hydrophobic ion-pair, 1,3-didecyl-2-methylimidazolium tetrakis(perf...

(This article belongs to the Special Issue Potentiometric Sensors in Analytical Chemistry)
  • Article
  • Open Access
462 Views
13 Pages

Aflatoxin B1 (AFB1), a highly carcinogenic mycotoxin, has been the focus of research for the development of efficient detection methods. In this study, a novel magnetic immuno-ratiometric fluorescent sensing system was constructed for the quantitativ...

(This article belongs to the Section Optical Chemical Sensors)
  • Article
  • Open Access
2 Citations
727 Views
16 Pages

Assessment of Cooked Meatballs’ Edibility Using Calibrated MOS Sensors and Microbiological Validation

  • Luigi Masi,
  • Revathy Gurusamy,
  • Daniel Garcia-Romeo,
  • Andreas Schütze and ,
  • Rafael Pagán and
  • Christian Bur
  • + 1 author+ 0 author

Food waste is often driven by consumer uncertainty about the spoilage of stored food, especially for cooked meal leftovers where microbial growth is the main concern. We analyzed whether metal oxide semiconductor (MOS) gas sensors placed inside ordin...

(This article belongs to the Special Issue Applications of Electronic Nose (E-Nose) and Electronic Tongue (E-Tongue) in Food Quality: 2nd Edition)
  • Article
  • Open Access
434 Views
21 Pages

This work aims to study and improve the long-term stability of conductimetric biosensors for urea detection in clinical and environmental samples, which are fundamentally limited by complex thermal and temporal drifts due to temperature-sensitive enz...

(This article belongs to the Topic Recent Advances in Chemical Artificial Intelligence)
  • Review
  • Open Access
548 Views
31 Pages

This manuscript will present an advancement of transformative research that has been conducted at Oak Ridge National Laboratory (ORNL) over a 25-year period (2000–2025) on a variety of environmental and biological matrices. These investigations...

(This article belongs to the Special Issue Application of Laser-Induced Breakdown Spectroscopy, 3rd Edition)
  • Article
  • Open Access
503 Views
19 Pages

Routine monitoring of ortho-phthalaldehyde (OPA) disinfectants is critical for endoscope reprocessing, yet commercial test strips suffer from subjective visual ambiguity, strict manual timing, and susceptibility to sample matrix dilution. This study...

(This article belongs to the Section Analytical Methods, Instrumentation and Miniaturization)
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Chemosensors - ISSN 2227-9040