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Chemosensors
Special Issues
Electrochemical Sensors and Biosensors: Recent Progress, Challenges, and Future Perspectives
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Electrochemical Sensors and Biosensors: Recent Progress, Challenges, and Future Perspectives

A special issue of Chemosensors (ISSN 2227-9040). This special issue belongs to the section "(Bio)chemical Sensing".

Deadline for manuscript submissions: 28 February 2027 | Viewed by 11943

Editor

Dr. Dongmei Dong

E-Mail Website
Guest Editor
Department of Physics and Astronomy, Rowan University, Glassboro, NJ 08028, USA
Interests: electrochemistry; thin solid films; electrochromic; sensors
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Electrochemical sensors and biosensors are crucial tools in modern science, offering unparalleled sensitivity, selectivity, and versatility for a wide range of applications. This Special Issue, titled “Electrochemical Sensors and Biosensors: Recent Progress, Challenges, and Future Perspectives”, aims to highlight the latest developments in sensor design, fabrication, characterization, and application. Contributions will focus on novel materials, such as nanomaterials, polymers, and composites, as well as cutting-edge techniques for enhancing performance and functionality. Topics will also include challenges in scaling up production, ensuring long-term stability, and improving biocompatibility for healthcare, environmental, and industrial applications. We invite researchers to share innovative solutions, interdisciplinary approaches, and insights into the future directions of electrochemical sensing technologies. By bridging gaps between fundamental research and real-world applications, this Special Issue will provide a comprehensive overview of the field's progress and challenges.

Dr. Dongmei Dong
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Chemosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • electrochemical sensors
  • biosensors
  • nanomaterials for sensing
  • advanced electrode materials
  • point-of-care diagnostics
  • environmental monitoring
  • biocompatibility
  • miniaturized sensors
  • signal enhancement techniques
  • real-time monitoring

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Published Papers (3 papers)

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Research

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22 pages, 5706 KB  
Article
Impact of Annealing Treatment on the Potential Stability of SUS316L and Its Possibility for Realizing a Quasi-Reference Electrode
by Kyosuke Sawada, Shinji Okazaki, Tatsuki Inaba and Motohiro Sakuma
Chemosensors 2025, 13(10), 356; https://doi.org/10.3390/chemosensors13100356 - 1 Oct 2025
Viewed by 1084
Abstract
This work demonstrates the use of SUS316L stainless steel as a new material for the fabrication of quasi-reference electrodes (QREs) intended to replace conventional reference electrodes (REs) in electrochemical sensors. The present study examined the potentials generated by SUS316L specimens annealed in air [...] Read more.
This work demonstrates the use of SUS316L stainless steel as a new material for the fabrication of quasi-reference electrodes (QREs) intended to replace conventional reference electrodes (REs) in electrochemical sensors. The present study examined the potentials generated by SUS316L specimens annealed in air at 400 °C and above for 1 h or more. Annealing above 500 °C increased the proportion of Cr in surface oxide films, hence reducing the stability of the potential. Samples annealed at 400 °C for 5 h produced the most stable electrode potential, which was attributed to a higher concentration of Fe in the oxide layer. The potential of such specimens increased by only 28.3 mV between test durations of 24 and 168 h, and potential data acquired at 30 s intervals had a standard deviation of less than 2 µV. Applying a surface treatment prior to immersion in the simulated tap water evidently stabilized the electrode potential, as a consequence of the formation of an inner oxide layer together with an outer layer consisting primarily of iron oxides. Full article
(This article belongs to the Special Issue Electrochemical Sensors and Biosensors: Recent Progress, Challenges, and Future Perspectives)
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Review

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50 pages, 9542 KB  
Review
Nanomaterial-Modified Screen-Printed Electrodes: Advances, Interfacial Engineering Evaluation, and Real-World Applications in Electrochemical Sensing
by Tudor-Alexandru Filip, Vlad-Andrei Scarlatache, Alin Dragomir, Georgiana Prodan-Chiriac and Marius-Andrei Olariu
Chemosensors 2026, 14(5), 107; https://doi.org/10.3390/chemosensors14050107 - 1 May 2026
Viewed by 1433
Abstract
Innovations in nanomaterial science, engineering and printing technologies have increasingly driven advances in electrochemical sensing. Screen-printed electrodes (SPEs) have become a versatile, low-cost, and scalable solution for developing portable electrochemical detection platforms. However, their analytical performance remains intrinsically limited by surface area, electron [...] Read more.
Innovations in nanomaterial science, engineering and printing technologies have increasingly driven advances in electrochemical sensing. Screen-printed electrodes (SPEs) have become a versatile, low-cost, and scalable solution for developing portable electrochemical detection platforms. However, their analytical performance remains intrinsically limited by surface area, electron transfer efficiency, and the immobilization of biomolecules. Recent developments in nanostructured materials, ranging from two-dimensional (2D) materials such as graphene, MXenes, and transition metal dichalcogenides, to one-dimensional nanostructures and hybrid nanocomposites, have transformed the signal transduction landscape of SPE-based electrochemical sensors. Integration of nanomaterials into SPEs has successfully transformed their analytical capabilities, but the diversity of materials and modification strategies has made it difficult to consolidate current knowledge in the field. Strategies that integrate nanomaterials via ink formulation, surface modification, or in situ growth have yielded sensors with unprecedented sensitivity, reproducibility, and selectivity across various chemical and biological targets. This review offers a cross-material synthesis of how nanomaterial engineering transforms the electrochemical performance of SPEs. By integrating insights across morphology, interfacial chemistry, and device-level behavior, it establishes a unified perspective that has been missing from the current literature and clarifies the design principles driving next-generation SPE-based sensing platforms. Full article
(This article belongs to the Special Issue Electrochemical Sensors and Biosensors: Recent Progress, Challenges, and Future Perspectives)
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34 pages, 2273 KB  
Review
The Development, Characteristics, and Challenges of Biosensors: The Example of Blood Glucose Meters
by Hsuan-Yu Chen and Chiachung Chen
Chemosensors 2025, 13(8), 300; https://doi.org/10.3390/chemosensors13080300 - 11 Aug 2025
Cited by 7 | Viewed by 8914
Abstract
Numerous research projects on biosensors have been conducted, and a substantial number of academic studies and conference papers on biosensors are published annually. However, only a few biosensors have been commercialized. In this review, we took blood glucose meters as an example to [...] Read more.
Numerous research projects on biosensors have been conducted, and a substantial number of academic studies and conference papers on biosensors are published annually. However, only a few biosensors have been commercialized. In this review, we took blood glucose meters as an example to review the development, characteristics, and challenges of biosensors in the literature. The four subsystems of the physical sensors are illustrated to emphasize the importance of standardization and traceability in the sensors. The development of physical sensors, chemical sensors, and biosensors is introduced. The importance of reference materials as a standard for evaluating sensor performance is emphasized. The basic technique and four types of chemical transducers are described, and we show that the biosensors’ response must be processed with these chemical sensors. The characteristics of the glucose meter are introduced to explain the success of this sensor, especially the sensing materials of glucosidases. Two types of highly developed and competitive biosensors, continuous glucose monitoring (CGM) and paper-based biosensors, are introduced, and the trends and future implications of both biosensors are illustrated. The challenges facing biosensor development are summarized into several key factors, and future research directions are discussed. A list of factors for the successful commercialization of biosensors is also proposed. Full article
(This article belongs to the Special Issue Electrochemical Sensors and Biosensors: Recent Progress, Challenges, and Future Perspectives)
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