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Chemosensors
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Advancements of Chemosensors and Biosensors in China—3rd Edition
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Advancements of Chemosensors and Biosensors in China—3rd Edition

A special issue of Chemosensors (ISSN 2227-9040).

Deadline for manuscript submissions: 30 June 2026 | Viewed by 2899

Editors

Prof. Dr. Chunsheng Wu

E-Mail Website
Guest Editor
Institute of Medical Engineering, School of Basic Medical Sciences, Xi’an Jiaotong University, Xi’an 710061, China
Interests: cell- and molecule-based biosensors; DNA biosensors; microfluidic chips; molecular diagnostics; micro/nano devices for chemical sensing; electrochemical sensors
Special Issues, Collections and Topics in MDPI journals
Dr. Liping Du

E-Mail Website
Guest Editor
Institute of Medical Engineering, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Xi'an Jiaotong University, Xi'an 710061, China
Interests: biosensor; chemical sensor; electrochemical devices and sensors; biomimetic sensor
Special Issues, Collections and Topics in MDPI journals
Dr. Wei Chen

E-Mail Website
Guest Editor
Institute of Medical Engineering, School of Basic Medical Sciences, Xi’an Jiaotong University, Xi’an 710061, China
Interests: MOFs; aptamer; PAMAM dendrimer; nanomaterials-based biosensors; polymer composites; electrospinning; cellulose; conductive polymer
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Chemosensors are devices that transform chemical information, ranging from the concentration of a specific sample component to total composition analysis, into an analytically useful signal. The development of efficient chemosensors and biosensors is highly important in various aspects of biomedical science and analytical and environmental science. This Special Issue will provide an overview of the frontiers and progress of chemosensors and biosensors in China.

Topics include but are not limited to the following:

  • Electrochemical sensors;
  • Optical chemical sensors;
  • Mass-sensitive sensors;
  • Field-effect transistor sensors;
  • Catalytic sensors;
  • Acoustic and thermal sensors;
  • Sensor array;
  • Innovative materials and their sensing applications;
  • Other sensors.

Prof. Dr. Chunsheng Wu
Dr. Liping Du
Dr. Wei Chen
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Chemosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • electrochemical sensors
  • optical chemical sensors
  • mass-sensitive sensors
  • field-effect transistor sensors
  • catalytic sensors
  • acoustic and thermal sensors
  • sensor array
  • innovative materials and their sensing applications
  • other sensors

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Related Special Issues

Published Papers (4 papers)

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Research

13 pages, 5578 KB  
Article
Gold Nanoparticle-Based Composite Electrode for Sensitive Electrochemical Detection of Melamine
by Liqin Cui, Kun Fan, Jia Ma, Yun Lu, Yanfang Wang and Jiao Yang
Chemosensors 2026, 14(6), 133; https://doi.org/10.3390/chemosensors14060133 - 10 Jun 2026
Viewed by 176
Abstract
Melamine, characterized by its high nitrogen content, has been illegally added to food and feed to falsely increase apparent protein levels. However, melamine and its metabolites pose serious risks to human and animal health, including kidney stones, renal failure, and even death, as [...] Read more.
Melamine, characterized by its high nitrogen content, has been illegally added to food and feed to falsely increase apparent protein levels. However, melamine and its metabolites pose serious risks to human and animal health, including kidney stones, renal failure, and even death, as well as potential carcinogenic effects. Therefore, accurate detection of trace melamine is of great importance and urgency. Electrochemical sensors based on nanomaterials have been widely used for melamine detection due to their high sensitivity, good selectivity, rapid response, and simple operation. In this work, a composite nanosheet-structured electrode was fabricated, and a dense layer of gold nanoparticles was modified on its surface to enhance electrochemical performance. Cyclic voltammetry and electrochemical impedance spectroscopy measurements indicated that this electrode exhibited highly sensitive electrochemical properties. In addition, differential pulse voltammetry was employed for melamine detection, and the results showed a wide linear range of 20–500 nM with an LOD of 4.7 nM. The proposed electrode enabled the detection of melamine in milk samples, exhibiting good anti-interference ability and long-term stability. Full article
(This article belongs to the Special Issue Advancements of Chemosensors and Biosensors in China—3rd Edition)
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14 pages, 6774 KB  
Article
Alternating Current Electroluminescent Sensor for Visual Detection of Trace Water in Oil
by Yuyang Li, Zhengying Wang, Shuangyang Kuang, Keyuan Ding, Xiaotian Zhu and Xiaoyan Wei
Chemosensors 2026, 14(6), 123; https://doi.org/10.3390/chemosensors14060123 - 24 May 2026
Viewed by 258
Abstract
The trace water content in industrial oil critically affects the operational stability and service life of industrial equipment and serves as a key indicator for evaluating oil quality. Therefore, the rapid, sensitive, and visual detection of trace water in oil is of great [...] Read more.
The trace water content in industrial oil critically affects the operational stability and service life of industrial equipment and serves as a key indicator for evaluating oil quality. Therefore, the rapid, sensitive, and visual detection of trace water in oil is of great engineering significance for equipment condition monitoring and early fault warning. Existing detection methods predominantly rely on precision instruments; although they enable quantitative analysis, their operational procedures are complicated and time-consuming, which are unsuitable for on-site real-time monitoring. Consequently, there is an urgent need for a novel trace water detection sensor that offers high sensitivity, visualization, and adaptability to oil-phase environments. Herein, a coplanar electrode alternating current electroluminescent (ACEL) sensor is developed for the visual detection of trace water in oil. The ACEL sensor features a multilayer structure comprising a substrate layer, a coplanar electrode layer, and a humidity-sensitive luminescent layer. The humidity-sensitive luminescent layer consists of humidity-sensitive hydrogel and ZnS: Cu electroluminescent powder, forming a loose and porous film that enables high-sensitivity humidity sensing and simultaneously electroluminescent visual signal output. The sensing mechanism study reveals that variations in trace water content modulate the dielectric properties of the humidity-sensitive layer, which further affect the electroluminescent intensity of the ACEL sensor. In addition, the ACEL sensor enables the rapid, naked-eye recognition of humidity changes under trace water conditions without the need for precision instruments, achieving a rapid response time of 3 s and a detection limit as low as 60 ppm, all making it applicable for different types of industrial oils. Thus, this ACEL sensor features a novel detection mechanism, excellent universality, fast response, and ease of operation, offering a new visual sensing strategy for trace water detection in industrial oil and holding broad prospects for practical applications. Full article
(This article belongs to the Special Issue Advancements of Chemosensors and Biosensors in China—3rd Edition)
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21 pages, 8567 KB  
Article
High-Performance Cataluminescence Sensor Based on UIO-66/HKUST-1 Composite for Rapid Detection of Dichloromethane
by Taoyou Zhou, Jingjie Fan, Pengyu Zhang, Yun Wang, Xiangxiang Wang, Lining Bao, Mingjian Yi, Yuxian Guo, Bai Sun, Lingtao Kong and Shuguang Zhu
Chemosensors 2026, 14(3), 58; https://doi.org/10.3390/chemosensors14030058 - 3 Mar 2026
Viewed by 922
Abstract
Dichloromethane, as a widely used highly volatile industrial solvent, has neurotoxicity and hepatotoxicity and is suspected of being a carcinogen to humans. Therefore, it is necessary to develop a detection method that is more convenient for users, responds faster and is more efficient [...] Read more.
Dichloromethane, as a widely used highly volatile industrial solvent, has neurotoxicity and hepatotoxicity and is suspected of being a carcinogen to humans. Therefore, it is necessary to develop a detection method that is more convenient for users, responds faster and is more efficient than traditional analytical techniques. In cataluminescence (CTL) technology, as a promising alternative, the performance of CTL sensors critically depends on the design of high-performance sensitive materials. In this study, by rationally designing two typical metal–organic frameworks (MOFs), UIO-66 (zirconium-based) and HKUST-1 (copper-based), UIO-66/HKUST-1 nanocomposites for dichloromethane CTL detection were prepared by using a simple hydrothermal method. The experimental results show that when the composition ratio of UIO-66 is 2%, this composite exhibits the strongest CTL response to dichloromethane. Under optimized conditions, this sensor exhibits high selectivity, excellent stability (RSD = 3.98%), and a rapid response advantage for dichloromethane. The response time and recovery time are 5 and 19 s, respectively. It shows a good linear relationship within the concentration range of 8.4–84 ppm, along with a detection limit as low as 1.71 ppm. Analysis indicates that the enhanced performance stems from the formation of high-concentration oxygen vacancies and significantly strengthened synergistic effects at the UIO-66/HKUST-1 composite. This increases the concentration of surface reactive oxygen species, thereby providing more active sites for catalytic reactions. This work provides a robust and efficient sensing strategy for dichloromethane detection. Full article
(This article belongs to the Special Issue Advancements of Chemosensors and Biosensors in China—3rd Edition)
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12 pages, 1632 KB  
Article
Polyethyleneimine-MOF-235 Composite-Enhanced Electrochemical Detection of Silver Nanoparticles in Cosmetics
by Shuo Duan and Huang Dai
Chemosensors 2025, 13(11), 392; https://doi.org/10.3390/chemosensors13110392 - 8 Nov 2025
Cited by 1 | Viewed by 996
Abstract
Silver nanoparticles (AgNPs) are extensively utilized in cosmetics and healthcare products, creating an urgent need for sensitive quantification methods. We report the first application of a metal–organic framework for electrochemical AgNPs sensing in cosmetic samples. A glassy carbon electrode was modified with polyethyleneimine-encapsulated [...] Read more.
Silver nanoparticles (AgNPs) are extensively utilized in cosmetics and healthcare products, creating an urgent need for sensitive quantification methods. We report the first application of a metal–organic framework for electrochemical AgNPs sensing in cosmetic samples. A glassy carbon electrode was modified with polyethyleneimine-encapsulated MOF-235 (PEI-MOF-235/GCE); the PEI layer enriches AgNPs through Ag–N coordination, whereas the high-surface-area MOF catalyzes their oxidative dissolution. Under optimized conditions (catalyst loading 1.4 µg mm−3, pH 4.3 PBS), differential-pulse voltammetry provided a linear range of 10–100 ng L−1 and a detection limit of 3.93 ng L−1 (S/N = 3). The sensor exhibited excellent stability (RSD ≤ 4.7%) and good anti-interference capability toward common aquatic ions. Compared with a standard HPLC method, recoveries in spiked cosmetic samples were 97.9–102.6%. This MOF-based strategy offers a sensitive, selective, and field-deployable platform for routine monitoring of trace AgNPs. Full article
(This article belongs to the Special Issue Advancements of Chemosensors and Biosensors in China—3rd Edition)
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