Rapid Point-of-Care Testing Technology and Application (Second Edition)

A special issue of Chemosensors (ISSN 2227-9040). This special issue belongs to the section "Analytical Methods, Instrumentation and Miniaturization".

Deadline for manuscript submissions: 30 November 2026 | Viewed by 727

Editors


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Guest Editor
National Institute for Research and Development in Microtechnologies—IMT Bucharest, 077190 Voluntari, Romania
Interests: nanotechnology-based diagnostic and drug delivery systems; diagnostic imaging; microfluidics; biosensors
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Analytical Chemistry, University of Bucharest, Bucharest, Romania
Interests: analytical chemistry; statistics; diagnostics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We would like to invite you to contribute to this Special Issue, “Rapid Point-of-Care Testing Technology and Application (Second Edition)”. Since the first diagnosed case of COVID-19 in 2019, it has continued to present a challenge to the medical and scientific world, necessitating ongoing efforts to understand the disease and specific approaches to it, from early diagnostics and adequate treatments to prophylaxis. Researchers play a significant role in developing solutions that facilitate diagnostic and prevention modalities at the POCT level; therefore, we seek contributions that can help us manage SARS-CoV-2 infections and progress to the next step: active control. In addition, as AI is gathering increasing interest, we will include new papers on AI-based devices for personalised approaches, such as animal-free point-of-care testing (POCT), medical care, and prophylactic medicine, in the era shaped by globalisation and technology.

Dr. Florina S. Iliescu
Dr. Zenovia Moldovan
Guest Editors

Manuscript Submission Information

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Keywords

  • SARS-CoV-2
  • POCT
  • diagnostic
  • microfluidics
  • biosensors
  • antibody
  • immune response
  • prophylaxis

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Published Papers (1 paper)

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Review

23 pages, 10805 KB  
Review
Functional Materials for Molecular POCT in Infectious Disease Detection: Advances and Regulatory Perspectives
by Yan Tan, Haonan Wu, Junjun Lan, Ting Qian, Xin Zhou, Shiyang Zhao and Hui Wang
Chemosensors 2026, 14(7), 163; https://doi.org/10.3390/chemosensors14070163 - 14 Jul 2026
Viewed by 317
Abstract
On-site nucleic acid analysis for infectious diseases can be rapidly achieved through molecular point-of-care testing (molecular POCT), which plays an indispensable role in early pathogen identification, timely clinical intervention, and public health emergency response. Performance improvements in such systems are largely driven by [...] Read more.
On-site nucleic acid analysis for infectious diseases can be rapidly achieved through molecular point-of-care testing (molecular POCT), which plays an indispensable role in early pathogen identification, timely clinical intervention, and public health emergency response. Performance improvements in such systems are largely driven by innovations in functional materials that refine nucleic acid extraction, amplification, and signal output. This article reviews recent developments in functional materials deployed in molecular POCT, with emphasis on nucleic acid capture matrices, amplification-promoting agents, and signal transduction components. From a medical device regulatory standpoint, we examine how material characteristics shape key analytical indicators, including sensitivity and specificity, and discuss critical risks such as off-target amplification and batch inconsistency. Finally, we outline future directions, highlighting cross-disciplinary cooperation to reconcile technological innovation with risk control for translating advanced materials into high-performance molecular POCT products. Full article
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