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Biology, Volume 8, Issue 4

December 2019 - 26 articles

Cover Story: The role of autophagy in cell survival and cell death decisions is highly dependent on its extent and on the respective cellular context. A pro-death function of autophagy may be exerted either via nonselective bulk autophagy or excessive (lethal) removal of mitochondria via selective mitophagy, opening new avenues for the therapeutic exploitation of autophagy in apopotisis-resistant cancers such as glioblastoma (GBM). The natural anticancer agent (-)-gossypol (AT-101) causes mitochondrial damage, including mitochondrial permeability transition pore (mPTP) opening, thereby inducing selective degradation of damaged mitochondria via mitophagy. In parallel, AT-101 induces the mitophagy receptors BNIP3 and BNIP3L/NIX, as well as the mitophagy-inducer HMOX1, further enhancing the extent of mitochondrial degradation and culminating in the demise of GBM cells via cell-lethal mitophagy. View this paper
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Articles (26)

  • Article
  • Open Access
5 Citations
4,350 Views
23 Pages

17 December 2019

The gametic lethal gene gal in combination with the semidwarfing gene d60 causes complementary lethality in rice. Here, we attempted to ascertain the existence of gal and clarify male gamete abortion caused by d60 and gal. Through the F2 to F4 genera...

  • Article
  • Open Access
22 Citations
5,417 Views
22 Pages

11 December 2019

Symbioses with soil microorganisms are central in shaping the diversity and productivity of land plants and provide protection against a diversity of stresses, including metal toxicity. Arbuscular mycorrhizal fungi (AMF) can form extensive extraradic...

  • Article
  • Open Access
49 Citations
8,564 Views
20 Pages

In Vitro Antidiabetic, Anti-Obesity and Antioxidant Analysis of Ocimum basilicum Aerial Biomass and in Silico Molecular Docking Simulations with Alpha-Amylase and Lipase Enzymes

  • Zoy I Noor,
  • Dildar Ahmed,
  • Hafiz Muzzammel Rehman,
  • Muhammad Tariq Qamar,
  • Matheus Froeyen,
  • Sarfraz Ahmad and
  • Muhammad Usman Mirza

4 December 2019

The present study explored phytochemicals, porcine pancreatic α-amylase (PPA) and lipase (PPL) inhibitory activities and antioxidant potential of polar and nonpolar extracts of the leaves and flowers of Ocimum basilicum and the in-silico mode o...

  • Article
  • Open Access
25 Citations
5,316 Views
14 Pages

Selection of Lactic Acid Bacteria (LAB) Antagonizing Vibrio parahaemolyticus: The Pathogen of Acute Hepatopancreatic Necrosis Disease (AHPND) in Whiteleg Shrimp (Penaeus vannamei)

  • Linh Nguyen Thi Truc,
  • Ai Trinh Ngoc,
  • To Tran Thi Hong,
  • Tuu Nguyen Thanh,
  • Huong Huynh Kim,
  • Long Pham Kim,
  • Giang Huynh Truong,
  • Phu Truong Quoc and
  • Tinh Nguyen Thi Ngoc

1 December 2019

Acute hepatopancreatic necrosis disease (AHPND) has recently emerged as a serious disease of cultured shrimp. A total of 19 lactic acid bacteria (LAB) strains isolated from shrimp samples were characterized based on morphological characteristics, bio...

  • Review
  • Open Access
96 Citations
11,351 Views
19 Pages

Advances in Omics Approaches for Abiotic Stress Tolerance in Tomato

  • Juhi Chaudhary,
  • Praveen Khatri,
  • Pankaj Singla,
  • Surbhi Kumawat,
  • Anu Kumari,
  • Vinaykumar R,
  • Amit Vikram,
  • Salesh Kumar Jindal,
  • Hemant Kardile and
  • Rahul Kumar
  • + 2 authors

25 November 2019

Tomato, one of the most important crops worldwide, has a high demand in the fresh fruit market and processed food industries. Despite having considerably high productivity, continuous supply as per the market demand is hard to achieve, mostly because...

  • Article
  • Open Access
19 Citations
5,521 Views
17 Pages

17 November 2019

Changes in environmental salinity challenge fish homeostasis and may affect physiological performance, such as swimming capacity and metabolism, which are important for foraging, migration, and escaping predators in the wild. The effects of salinity...

  • Article
  • Open Access
21 Citations
10,012 Views
26 Pages

Reproductive Biology and Ecology of the Green Mussel Perna viridis: A Multidisciplinary Approach

  • Md Asaduzzaman,
  • Aysha Rahi Noor,
  • Md Moshiur Rahman,
  • Sumi Akter,
  • Nayeema Ferdausy Hoque,
  • Abrar Shakil and
  • Md Abdul Wahab

15 November 2019

A multidisciplinary approach was applied to explore deeper knowledge about the reproductive biology and ecology of the green mussel (Perna viridis) by interlinking among ecological factors, ingested gut plankton, gonad fatty acid profile, and reprodu...

  • Article
  • Open Access
5 Citations
4,383 Views
12 Pages

14 November 2019

Anthropogenic eutrophication has caused widespread environmental problems in freshwater lakes, reducing biodiversity and disrupting the classic pelagic food chain. Increasing our understanding of the exact role of nutrients and physicochemical variab...

  • Article
  • Open Access
5 Citations
3,723 Views
21 Pages

13 November 2019

Uncharacterized protein STY1099, encoded by the yccT gene, was previously identified as the most altered (i.e., upregulated) protein among the ZnO nanoparticle (NP) stimulon of Salmonella enterica serovar Enteritidis. Here we combined various stress...

  • Article
  • Open Access
16 Citations
3,514 Views
18 Pages

Cryotolerance of Stallion Spermatozoa Relies on Aquaglyceroporins rather than Orthodox Aquaporins

  • Ariadna Delgado-Bermúdez,
  • Federico Noto,
  • Sebastián Bonilla-Correal,
  • Estela Garcia-Bonavila,
  • Jaime Catalán,
  • Marion Papas,
  • Sergi Bonet,
  • Jordi Miró and
  • Marc Yeste

12 November 2019

Aquaporins (AQPs), a family of ubiquitous water channels divided into orthodox AQPs, aquaglyceroporins (GLPs), and superAQPs, are present in stallion spermatozoa. The aim of this study was to elucidate the functional relevance of each group of AQPs d...

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Biology - ISSN 2079-7737Creative Common CC BY license