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Journal of Clinical Medicine, Volume 14, Issue 13

July-1 2025 - 424 articles

Cover Story: Venous thromboembolism (VTE) is a major source of preventable morbidity in neurocritically ill patients, yet the optimal timing and agent for pharmacologic thromboprophylaxis (PTP) remain uncertain. In this review of 90 studies, including 669,725 patients with traumatic brain injury, intracerebral hemorrhage, subarachnoid hemorrhage, or spinal cord injury, or those requiring neurosurgical intervention, early PTP (within 24–72 hours) was generally associated with reduced VTE risk without a consistently increased risk of bleeding. Enoxaparin showed potential benefits over unfractionated heparin in certain subgroups. Safety may be improved in some injury types, with early repeat imaging suggesting stable bleeding. Despite variability in study designs and quality, this updated assessment of the literature supports early, individualized PTP strategies. View this paper
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Articles (424)

  • Article
  • Open Access
3,121 Views
13 Pages

Association of Atrial Fibrillation with Incident Probable Dementia and Cognitive Impairment in the Systolic Blood Pressure Intervention Trial (SPRINT)

  • Parham Samimisedeh,
  • Richard Kazibwe,
  • Christopher L. Schaich,
  • Timothy M. Hughes and
  • Elsayed Z. Soliman

7 July 2025

Background: The association between atrial fibrillation (AF) and dementia and cognitive decline in individuals with hypertension is not well established. Methods: The Systolic Blood Pressure Intervention Trial (SPRINT) enrolled participants with hype...

  • Article
  • Open Access
1,651 Views
13 Pages

7 July 2025

Background: Patients with ST-elevation myocardial infarction (STEMI) and multivessel coronary artery disease (MVD) who undergo complete revascularization (CR) have a more favorable prognosis than those who receive incomplete revascularization (IR), a...

  • Article
  • Open Access
3,291 Views
14 Pages

The Efficacy of Albumin Infusion in Septic Patients with Hypoalbuminemia: An International Retrospective Observational Study

  • Hsin-Yu Liu,
  • Yu-Ching Chen,
  • Ju-Fang Liu,
  • Pei-Sung Hsu,
  • Wen-Pin Cheng and
  • Shih-Sen Lin

7 July 2025

Background/Objectives: Albumin supplementation is widely used for hypoalbuminemia treatment in patients with critical illness, especially those with cirrhosis. However, studies have demonstrated that routine albumin administration is not always advan...

  • Review
  • Open Access
2 Citations
2,889 Views
21 Pages

7 July 2025

The reconstruction of a severely resorbed alveolar bone is a significant challenge in dental implantology and maxillofacial surgery. Traditional bone grafting materials, including autogenous, allogeneic, xenogeneic, and alloplastic materials, have li...

  • Review
  • Open Access
1 Citations
2,452 Views
15 Pages

7 July 2025

Intraoperative cell salvage (ICS) is a blood conservation technique utilized in major surgery, yet its application in oncologic procedures remains debated. Concerns persist about the theoretical risk of metastasis through reinfusion of tumor cells, d...

  • Article
  • Open Access
1 Citations
1,164 Views
16 Pages

Right Atrial Pressure/Pulmonary Capillary Wedge Pressure Ratio Predicts In-Hospital Mortality in Left Ventricular Assist Device Recipients

  • Berhan Keskin,
  • Aykun Hakgor,
  • Bilge Yilmaz,
  • Korhan Erkanli,
  • Beytullah Cakal,
  • Arzu Yazar,
  • Yahya Yildiz,
  • Bilal Boztosun and
  • Ibrahim Oguz Karaca

7 July 2025

Background/Objectives: Right ventricular failure (RVF) is a major contributor to early mortality after left ventricular assist device (LVAD) implantation. While various markers of right ventricular function and right ventriculoarterial coupling have...

  • Article
  • Open Access
859 Views
9 Pages

Three-Dimensional Model Improves Body Image Perception After Bariatric Surgery

  • Cyril Gauthier,
  • Matthieu Poussier,
  • Célia Lloret-Linares,
  • Marc Danan and
  • Anamaria Nedelcu

7 July 2025

Background: Despite losing weight, the majority of subjects retained an obese view of themselves. The aim of the study was to evaluate the usefulness of a 3D modeling tool in improving the body image of patients who have undergone bariatric surgery....

  • Feature Paper
  • Review
  • Open Access
2 Citations
14,242 Views
21 Pages

7 July 2025

Transthyretin-related (ATTR) amyloidosis is a progressive, multisystem disease caused by the extracellular deposition of misfolded transthyretin (TTR) monomers as insoluble amyloid fibrils. Clinical manifestations vary widely and may include cardiomy...

  • Article
  • Open Access
1 Citations
2,343 Views
10 Pages

Microencapsulated Sodium Butyrate in the Prevention of Acute Radiotherapy Proctitis: Single-Center Prospective Study

  • Renato Cannizzaro,
  • Stefania Maiero,
  • Paola Pelizzo,
  • Marco Gulotta,
  • Sonia Facchin,
  • Giulia Tessarolo,
  • Antonella Zucchetto,
  • Fabio Matrone,
  • Stefano Realdon and
  • Roberto Bortolus

7 July 2025

Background/Objectives: Prostate cancer is the most frequent cancer in men, for which Radiotherapy (RT) is used as a radical or post-surgical treatment. Actinic proctitis is one of the most disabling side effects of RT. Intestinal microbiome studies h...

  • Protocol
  • Open Access
1,184 Views
18 Pages

Glucose Homeostasis, Metabolomics, and Pregnancy Outcomes After Bariatric Surgery (GLORIA): Protocol for a Multicentre Prospective Cohort Study

  • Ellen Deleus,
  • Niels Bochanen,
  • Dries Ceulemans,
  • Hanne Debunne,
  • Bénédicte Denys,
  • Roland Devlieger,
  • Ina Geerts,
  • Annouschka Laenen,
  • Lisbeth Jochems and
  • Els Lannoey
  • + 13 authors

7 July 2025

Background: Metabolic bariatric surgery is a highly effective and long-lasting treatment for obesity and related chronic conditions. Women of reproductive age represent the largest group undergoing these procedures. Observational studies suggest an i...

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J. Clin. Med. - ISSN 2077-0383