Dear Colleagues,

Recent advances in diagnostic procedures and therapeutic interventions in Multiple sclerosis have substantially improved disease management and outcome. During the last decade, diagnostic criteria have been refined and allowed an earlier diagnosis, while preclinical conditions such as radiologically isolated syndrome, have been extensively studied. Current research explores the feasibility of the use of advanced neuroimaging techniques and blood biomarkers such as the levels of neurofilament light chains, in clinical practice. Future perspectives include the implementation of digital monitoring tools in everyday clinical practice that may allow early detection and prevention of disease worsening.

This Special Issue of the Journal of clinical medicine seeks commentaries, case reports, original research, short reports, and reviews focusing on the advances in research, diagnosis monitoring and treatment of multiple sclerosis and other demyelinating disorders such as neuromyelitis optica and MOG-associated diseases. This Special Issue aims to provide information about advances in phenotyping people with demyelinating disorders, personalization of treatment and long-term monitoring of these disease entities.

Prof. Dr. Nikolaos Grigoriadis
Dr. Maria Eleptheria Evangelopoulos
Dr. Christos Bakirtzis
Guest Editors

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• multiple sclerosis
• demyelination
• disease modifying therapies
• neurodegeneration
• neuromyelitis optica
• disease monitoring
• diagnostic criteria