Membranes, Volume 15, Issue 9
2025 September - 35 articles
Cover Story: Hollow fiber membrane oxygenators are lifesaving devices used in extracorporeal membrane oxygenation (ECMO) for patients with severe lung failure. Computational fluid dynamics (CFD) has been used to design and optimize such oxygenators. However, current CFD models are limited by their simplified models of blood gas exchange, neglecting the physiological phenomenon. For the first time, this study presents a validated CFD model that incorporates the Bohr and Haldane effects to couple oxygen and carbon dioxide transport. The proposed model achieves excellent results with experimental data and outperforms previous approaches. The framework provides new opportunities to optimize oxygenator design and improve clinical performance by capturing physiologically realistic gas exchange. View this paper - Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
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