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Microorganisms, Volume 8, Issue 3

2020 March - 149 articles

Cover Story: Siboglinidae worms are known to host chemosynthetic endosymbionts in a dedicated trophosome organ. However, little is known about their tube as a potential niche for other microorganisms. In this study, siboglinids sampled from four mud volcanoes in the Gulf of Cádiz (El Cid MV, Bonjardim MV, Al Gacel MV, and Anastasya MV) revealed that the tube was colonized by a thick microbial biofilm. This external biofilm of the tubes was mostly composed of cell-aggregations of methanotrophic bacteria, but other morphotypes such as filamentous, prosthecate, spirillum-like and rod-shaped bacteria were also observed. Yet, these microorganisms seem to influence in the structure and composition of the tube. Thus, siboglinids’ tubes remarkably increase the microbial biomass related to the worms and provide an additional microbial niche in deep-sea ecosystems.View this paper.
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Articles (149)

  • Article
  • Open Access
2 Citations
4,084 Views
7 Pages

Multicenter Evaluation of the C6 Lyme ELISA Kit for the Diagnosis of Lyme Disease

  • Silvia Zannoli,
  • Michela Fantini,
  • Simona Semprini,
  • Barbara Marchini,
  • Barbara Ceccarelli,
  • Monica Sparacino,
  • Pasqua Schiavone,
  • Anna Belgrano,
  • Maurizio Ruscio and
  • Vittorio Sambri
  • + 4 authors

Lyme disease (LD), caused by infection with Borrelia burgdorferi, is the most common tick-borne infection in many regions of Eurasia. Antibody detection is the most frequently used laboratory test, favoring a two-step serodiagnostic algorithm; immuno...

  • Article
  • Open Access
55 Citations
6,289 Views
21 Pages

Epidemiological Surveillance of Norovirus and Rotavirus in Sewage (2016–2017) in Valencia (Spain)

  • Cristina Santiso-Bellón,
  • Walter Randazzo,
  • Alba Pérez-Cataluña,
  • Susana Vila-Vicent,
  • Roberto Gozalbo-Rovira,
  • Carlos Muñoz,
  • Javier Buesa,
  • Gloria Sanchez and
  • Jesús Rodríguez Díaz

The aim of the present study was to perform the molecular epidemiology of rotaviruses and noroviruses detected in sewage samples from a large wastewater facility from the city of Valencia, Spain. A total of 46 sewage samples were collected over a one...

  • Article
  • Open Access
32 Citations
3,931 Views
19 Pages

First Report on the Prevalence and Subtype Distribution of Blastocystis sp. in Edible Marine Fish and Marine Mammals: A Large Scale-Study Conducted in Atlantic Northeast and on the Coasts of Northern France

  • Nausicaa Gantois,
  • Angélique Lamot,
  • Yuwalee Seesao,
  • Colette Creusy,
  • Luen-Luen Li,
  • Sébastien Monchy,
  • Sadia Benamrouz-Vanneste,
  • Jacky Karpouzopoulos,
  • Jean-Luc Bourgain and
  • Eric Viscogliosi
  • + 8 authors

Blastocystis is frequently identified in humans and animal hosts and exhibits a large genetic diversity with the identification of 17 subtypes (STs). Despite its zoonotic potential, its prevalence and ST distribution in edible marine fish and marine...

  • Article
  • Open Access
4 Citations
3,975 Views
12 Pages

Unraveling the Fungal Community Associated with Leaf Spot on Crataegus sp.

  • Sonia Salazar-Cerezo,
  • María de la Cruz Meneses-Sánchez,
  • Rebeca D. Martínez-Contreras and
  • Nancy Martínez-Montiel

Crataegus sp. is a tree that grows in temperate zones with worldwide distribution and is commonly known in Mexico as tejocote. The use of products derived from Crataegus in traditional medicine, food, and cosmetics has increased over the last few yea...

  • Review
  • Open Access
7 Citations
5,172 Views
18 Pages

Vast evolutionary distances separate the known herpesviruses, adapted to colonise specialised cells in predominantly vertebrate hosts. Nevertheless, the distinct herpesvirus families share recognisably related genomic attributes. The taxonomic Family...

  • Review
  • Open Access
81 Citations
10,384 Views
18 Pages

As the major postharvest disease of citrus fruit, postharvest green mold is caused by the necrotrophic fungus Penicillium digitatum (Pd), which leads to huge economic losses worldwide. Fungicides are still the main method currently used to control po...

  • Article
  • Open Access
8 Citations
3,623 Views
10 Pages

Liver Transudate, a Potential Alternative to Detect Anti-Hepatitis E Virus Antibodies in Pigs and Wild Boars (Sus scrofa)

  • Alejandro Navarro,
  • Carmen Bárcena,
  • Pilar Pozo,
  • Alberto Díez-Guerrier,
  • Irene Martínez,
  • Coral Polo,
  • Clara Duque,
  • David Rodríguez-Lázaro,
  • Joaquín Goyache and
  • Nerea García

In recent years, cases of hepatitis E virus (HEV) infection have increased in Europe in association with the consumption of contaminated food, mainly from pork products but also from wild boars. The animal’s serum is usually tested for the pres...

  • Article
  • Open Access
27 Citations
7,276 Views
15 Pages

Deinococcus radiodurans is known for its extreme resistance to ionizing radiation, oxidative stress, and other DNA-damaging agents. The robustness of this bacterium primarily originates from its strong oxidative resistance mechanisms. Hundreds of gen...

  • Review
  • Open Access
35 Citations
5,977 Views
11 Pages

Bridging the Gap: A Role for Campylobacter jejuni Biofilms

  • Greg Tram,
  • Christopher J. Day and
  • Victoria Korolik

Campylobacter jejuni is the leading cause of bacterial gastroenteritis in the developed world. Cases of Campylobacteriosis are common, as the organism is an avian commensal and is passed on to humans through contaminated poultry meat, water, and food...

  • Article
  • Open Access
11 Citations
3,715 Views
18 Pages

Lipids from oleaginous microorganisms, including oleaginous yeasts, are recognized as feedstock for biodiesel production. A production process development of these organisms is necessary to bring lipid feedstock production up to the industrial scale....

  • Article
  • Open Access
10 Citations
6,723 Views
20 Pages

Formate Utilization by the Crenarchaeon Desulfurococcus amylolyticus

  • Ipek Ergal,
  • Barbara Reischl,
  • Benedikt Hasibar,
  • Lokeshwaran Manoharan,
  • Aaron Zipperle,
  • Günther Bochmann,
  • Werner Fuchs and
  • Simon K.-M. R. Rittmann

Formate is one of the key compounds of the microbial carbon and/or energy metabolism. It owes a significant contribution to various anaerobic syntrophic associations, and may become one of the energy storage compounds of modern energy biotechnology....

  • Article
  • Open Access
69 Citations
6,699 Views
13 Pages

Quorum sensing (QS) plays an important role during infection for the opportunistic human pathogen Pseudomonas aeruginosa. Quorum sensing inhibition (QSI) can disrupt this initial event of infection without killing bacterial cells, and thus QS inhibit...

  • Article
  • Open Access
19 Citations
5,099 Views
18 Pages

Fungal Microbiota of Sea Buckthorn Berries at Two Ripening Stages and Volatile Profiling of Potential Biocontrol Yeasts

  • Juliana Lukša,
  • Iglė Vepštaitė-Monstavičė,
  • Violeta Apšegaitė,
  • Laima Blažytė-Čereškienė,
  • Ramunė Stanevičienė,
  • Živilė Strazdaitė-Žielienė,
  • Bazilė Ravoitytė,
  • Dominykas Aleknavičius,
  • Vincas Būda and
  • Elena Servienė
  • + 1 author

Sea buckthorn, Hippophae rhamnoides L., has considerable potential for landscape reclamation, food, medicinal, and cosmetics industries. In this study, we analyzed fungal microorganism populations associated with carposphere of sea buckthorn harveste...

  • Article
  • Open Access
29 Citations
6,706 Views
28 Pages

Whole Genome Sequencing Differentiates Presumptive Extended Spectrum Beta-Lactamase Producing Escherichia coli along Segments of the One Health Continuum

  • Emelia H. Adator,
  • Matthew Walker,
  • Claudia Narvaez-Bravo,
  • Rahat Zaheer,
  • Noriko Goji,
  • Shaun R. Cook,
  • Lisa Tymensen,
  • Sherry J. Hannon,
  • Deirdre Church and
  • Tim A. McAllister
  • + 4 authors

Antimicrobial resistance (AMR) has important implications for the continued use of antibiotics to control infectious diseases in both beef cattle and humans. AMR along the One Health continuum of the beef production system is largely unknown. Here, w...

  • Article
  • Open Access
29 Citations
6,185 Views
15 Pages

Most double-stranded (ds) DNA phages utilize holin proteins to secrete endolysin for host peptidoglycan lysis. In contrast, several holin-independent endolysins with secretion sequences or signal-arrest-release (SAR) sequences are secreted via the Se...

  • Article
  • Open Access
51 Citations
5,158 Views
12 Pages

Prevalence, Antimicrobial Resistance, Virulence Genes and Genetic Diversity of Salmonella Isolated from Retail Duck Meat in Southern China

  • Zhengquan Chen,
  • Jie Bai,
  • Shaojun Wang,
  • Xibin Zhang,
  • Zeqiang Zhan,
  • Haiyan Shen,
  • Hongxia Zhang,
  • Junping Wen,
  • Yuan Gao and
  • Jianmin Zhang
  • + 1 author

Salmonella is an important cause of foodborne diseases. This study was undertaken to investigate the prevalence, serotype distribution, antimicrobial resistance, virulence genes, and genetic diversity of Salmonella isolates recovered from fresh duck...

  • Article
  • Open Access
22 Citations
3,664 Views
11 Pages

Evaluation of Cyprinid Herpesvirus 2 Latency and Reactivation in Carassius gibel

  • Wenjun Chai,
  • Lin Qi,
  • Yujun Zhang,
  • Mingming Hong,
  • Ling Jin,
  • Lijuan Li and
  • Junfa Yuan

Cyprinid herpesvirus 2 (CyHV-2, species Cyprinid herpesvirus 2) causes severe mortality in ornamental goldfish, crucian carp (Carassius auratus), and gibel carp (Carassius gibelio). It has been shown that the genomic DNA of CyHV-2 could be detected i...

  • Review
  • Open Access
39 Citations
7,009 Views
12 Pages

Do Foliar Endophytes Matter in Litter Decomposition?

  • Emily R. Wolfe and
  • Daniel J. Ballhorn

Litter decomposition rates are affected by a variety of abiotic and biotic factors, including the presence of fungal endophytes in host plant tissues. This review broadly analyzes the findings of 67 studies on the roles of foliar endophytes in litter...

  • Article
  • Open Access
22 Citations
4,009 Views
14 Pages

Brucellosis is a major zoonotic public health threat worldwide, causing veterinary morbidity and major economic losses in endemic regions. However, no efficacious brucellosis vaccine is yet available, and live attenuated vaccines commonly used in ani...

  • Article
  • Open Access
59 Citations
5,476 Views
19 Pages

The Interplay between Mucosal Microbiota Composition and Host Gene-Expression is Linked with Infliximab Response in Inflammatory Bowel Diseases

  • Nikolas Dovrolis,
  • George Michalopoulos,
  • George E. Theodoropoulos,
  • Kostantinos Arvanitidis,
  • George Kolios,
  • Leonardo A. Sechi,
  • Aristidis G. Eliopoulos and
  • Maria Gazouli

Even though anti-TNF therapy significantly improves the rates of remission in inflammatory bowel disease (IBD) patients, there is a noticeable subgroup of patients who do not respond to treatment. Dysbiosis emerges as a key factor in IBD pathogenesis...

  • Article
  • Open Access
27 Citations
6,957 Views
19 Pages

Methylosinus trichosporium OB3b is an obligate aerobic methane-utilizing alpha-proteobacterium. Since its isolation, M. trichosporium OB3b has been established as a model organism to study methane metabolism in type II methanotrophs. M. trichosporium...

  • Article
  • Open Access
28 Citations
4,231 Views
15 Pages

Lactobacillus paracasei A13 and High-Pressure Homogenization Stress Response

  • Lorenzo Siroli,
  • Giacomo Braschi,
  • Samantha Rossi,
  • Davide Gottardi,
  • Francesca Patrignani and
  • Rosalba Lanciotti

Sub-lethal high-pressure homogenization treatments applied to Lactobacillus paracasei A13 demonstrated to be a useful strategy to enhance technological and functional properties without detrimental effects on the viability of this strain. Modificatio...

  • Brief Report
  • Open Access
9 Citations
5,255 Views
8 Pages

Seroprevalence in Bats and Detection of Borrelia burgdorferi in Bat Ectoparasites

  • Arinjay Banerjee,
  • Kaushal Baid,
  • Taylor Byron,
  • Alyssa Yip,
  • Caleb Ryan,
  • Prasobh Raveendran Thampy,
  • Hugh Broders,
  • Paul Faure and
  • Karen Mossman

The role of bats in the enzootic cycle of Lyme disease and relapsing fever-causing bacteria is a matter of speculation. In Canada, Borrelia burgdorferi sensu stricto (ss) is the genospecies that is responsible for most cases of Lyme disease in humans...

  • Article
  • Open Access
7 Citations
3,920 Views
18 Pages

Taxonomic Characterization and Secondary Metabolite Analysis of NEAU-wh3-1: An Embleya Strain with Antitumor and Antibacterial Activity

  • Han Wang,
  • Tianyu Sun,
  • Wenshuai Song,
  • Xiaowei Guo,
  • Peng Cao,
  • Xi Xu,
  • Yue Shen and
  • Junwei Zhao

Cancer is a serious threat to human health. With the increasing resistance to known drugs, it is still urgent to find new drugs or pro-drugs with anti-tumor effects. Natural products produced by microorganisms have played an important role in the his...

  • Article
  • Open Access
99 Citations
11,728 Views
22 Pages

In the midst of the major soil degradation and erosion faced by tropical ecosystems, rehabilitated forests are being established to avoid the further deterioration of forest lands. In this context, cellulolytic, nitrogen-fixing (N-fixing), phosphate-...

  • Article
  • Open Access
49 Citations
12,327 Views
19 Pages

We assessed the diversity, structure, and assemblage of bacterial and fungal communities associated with banana plants with and without Fusarium oxysporum f. sp. cubense (Foc) symptoms. A total of 117,814 bacterial and 17,317 fungal operational taxon...

  • Article
  • Open Access
59 Citations
7,823 Views
18 Pages

Optimised Production and Extraction of Astaxanthin from the Yeast Xanthophyllomyces dendrorhous

  • Zuharlida Tuan Harith,
  • Micael de Andrade Lima,
  • Dimitris Charalampopoulos and
  • Afroditi Chatzifragkou

Currently, astaxanthin demand is fulfilled by chemical synthesis using petroleum-based feedstocks. As such, alternative pathways of natural astaxanthin production attracts much research interest. This study aimed at optimising bioreactor operation pa...

  • Article
  • Open Access
29 Citations
5,119 Views
9 Pages

The Obesity-Related Gut Bacterial and Viral Dysbiosis Can Impact the Risk of Colon Cancer Development

  • Giuseppina Campisciano,
  • Nicolò de Manzini,
  • Serena Delbue,
  • Carolina Cason,
  • Davide Cosola,
  • Giuseppe Basile,
  • Pasquale Ferrante,
  • Manola Comar and
  • Silvia Palmisano

An incorrect food regimen from childhood is suggested to negatively impact the gut microbiome composition leading to obesity and perhaps to colon rectal cancer (CRC) in adults. In this study, we show that the obesity and cancer gut microbiota share a...

  • Article
  • Open Access
9 Citations
3,691 Views
14 Pages

Small Sample Stress: Probing Oxygen-Deprived Ammonia-Oxidizing Bacteria with Raman Spectroscopy In Vivo

  • Ann-Kathrin Kniggendorf,
  • Regina Nogueira,
  • Somayeh Nasiri Bahmanabad,
  • Andreas Pommerening-Röser and
  • Bernhard Wilhelm Roth

The stress response of ammonia-oxidizing bacteria (AOB) to oxygen deprivation limits AOB growth and leads to different nitrification pathways that cause the release of greenhouse gases. Measuring the stress response of AOB has proven to be a challeng...

  • Article
  • Open Access
30 Citations
5,013 Views
22 Pages

Understanding the interactions of soil microbial species and how they responded to disturbances are essential to ecological restoration and resilience in the semihumid and semiarid damaged mining areas. Information on this, however, remains unobvious...

  • Review
  • Open Access
258 Citations
18,944 Views
40 Pages

An Overview of Potential Oleaginous Microorganisms and Their Role in Biodiesel and Omega-3 Fatty Acid-Based Industries

  • Alok Patel,
  • Dimitra Karageorgou,
  • Emma Rova,
  • Petros Katapodis,
  • Ulrika Rova,
  • Paul Christakopoulos and
  • Leonidas Matsakas

Microorganisms are known to be natural oil producers in their cellular compartments. Microorganisms that accumulate more than 20% w/w of lipids on a cell dry weight basis are considered as oleaginous microorganisms. These are capable of synthesizing...

  • Communication
  • Open Access
10 Citations
5,777 Views
10 Pages

OXA-48 Carbapenemase in Klebsiella pneumoniae Sequence Type 307 in Ecuador

  • José E. Villacís,
  • Jorge A. Reyes,
  • Hugo G. Castelán-Sánchez,
  • Sonia Dávila-Ramos,
  • Miguel Angel Lazo,
  • Ahmad Wali,
  • Luis A. Bodero,
  • Yadira Toapanta,
  • Cristina Naranjo and
  • Mónica C. Gestal
  • + 3 authors

Antibiotic resistance is on the rise, leading to an increase in morbidity and mortality due to infectious diseases. Klebsiella pneumoniae is a Gram-negative bacterium that causes bronchopneumonia, abscesses, urinary tract infection, osteomyelitis, an...

  • Article
  • Open Access
35 Citations
4,665 Views
15 Pages

Deep Insights into Gut Microbiota in Four Carnivorous Coral Reef Fishes from the South China Sea

  • Yu-Miao Gao,
  • Ke-Shu Zou,
  • Lei Zhou,
  • Xian-De Huang,
  • Yi-Yang Li,
  • Xiang-Yang Gao,
  • Xiao Chen and
  • Xiao-Yong Zhang

Investigations of gut microbial diversity among fish to provide baseline data for wild marine fish, especially the carnivorous coral reef fishes of the South China Sea, are lacking. The present study investigated the gut microbiota of four carnivorou...

  • Review
  • Open Access
59 Citations
7,978 Views
11 Pages

Dietary Carbohydrate Constituents Related to Gut Dysbiosis and Health

  • Ye Seul Seo,
  • Hye-Bin Lee,
  • Yoonsook Kim and
  • Ho-Young Park

Recent studies report that microbiota in the human intestine play an important role in host health and that both long- and short-term diets influence gut microbiota. These findings have fueled interest in the potential of food to promote health by sh...

  • Article
  • Open Access
30 Citations
7,552 Views
16 Pages

Yeasts and Bacterial Consortia from Kefir Grains Are Effective Biocontrol Agents of Postharvest Diseases of Fruits

  • V. Yeka Zhimo,
  • Antonio Biasi,
  • Ajay Kumar,
  • Oleg Feygenberg,
  • Shoshana Salim,
  • Silvana Vero,
  • Michael Wisniewski and
  • Samir Droby

Fungal pathogens in fruits and vegetables cause significant losses during handling, transportation, and storage. Biological control with microbial antagonists replacing the use of chemical fungicides is a major approach in postharvest disease control...

  • Brief Report
  • Open Access
23 Citations
4,088 Views
7 Pages

In this study, we report the presence of the plasmid-mediated colistin resistance (PMCR)-encoding gene mcr-1 in an Escherichia coli isolate, INSali25, recovered from lettuce produced and marketed in Portugal. Colistin MIC from the vegetable E. coli i...

  • Article
  • Open Access
35 Citations
4,983 Views
14 Pages

Chemical Composition of an Aphid Antifeedant Extract from an Endophytic Fungus, Trichoderma sp. EFI671

  • Nutan Kaushik,
  • Carmen E. Díaz,
  • Hemraj Chhipa,
  • L. Fernando Julio,
  • M. Fe Andrés and
  • Azucena González-Coloma

Botanical and fungal biopesticides, including endophytes, are in high demand given the current restrictive legislations on the use of chemical pesticides. As part of an ongoing search for new biopesticides, a series of fungal endophytes have been iso...

  • Article
  • Open Access
12 Citations
4,957 Views
16 Pages

Microbiota Alters Urinary Bladder Weight and Gene Expression

  • Blanka Roje,
  • Anamaria Elek,
  • Vinko Palada,
  • Joana Bom,
  • Aida Iljazović,
  • Ana Šimić,
  • Lana Sušak,
  • Katarina Vilović,
  • Till Strowig and
  • Janoš Terzić
  • + 1 author

We studied the effect of microbiota on the transcriptome and weight of the urinary bladder by comparing germ-free (GF) and specific pathogen-free (SPF) housed mice. In total, 97 genes were differently expressed (fold change > ±2; false disc...

  • Article
  • Open Access
9 Citations
4,124 Views
21 Pages

Phylogenetic Grouping of Human Ocular Escherichia coli Based on Whole-Genome Sequence Analysis

  • Konduri Ranjith,
  • Chinthala Reddy SaiAbhilash,
  • Gumpili Sai Prashanthi,
  • Shalem Raj Padakandla,
  • Savitri Sharma and
  • Sisinthy Shivaji

Escherichia coli is a predominant bacterium in the intestinal tracts of animals. Phylogenetically, strains have been classified into seven phylogroups, A, B1, B2, C, D, E, and F. Pathogenic strains have been categorized into several pathotypes such a...

  • Article
  • Open Access
23 Citations
4,266 Views
22 Pages

The Structure and Diversity of Nitrogen Functional Groups from Different Cropping Systems in Yellow River Delta

  • Huan He,
  • Yongjun Miao,
  • Lvqing Zhang,
  • Yu Chen,
  • Yandong Gan,
  • Na Liu,
  • Liangfeng Dong,
  • Jiulan Dai and
  • Weifeng Chen

The Yellow River Delta (YRD) region is an important production base in Shandong Province. It encompasses an array of diversified crop systems, including the corn–wheat rotation system (Wheat–Corn), soybean–corn rotation system (Soyb...

  • Brief Report
  • Open Access
5 Citations
3,390 Views
12 Pages

Overexpression of Semaphorin 3A Is a Marker Associated with Poor Prognosis in Patients with Nasopharyngeal Carcinoma

  • Tomoko Imoto,
  • Satoru Kondo,
  • Naohiro Wakisaka,
  • Pham Tahnh Hai,
  • Noriko Seishima,
  • Makoto Kano,
  • Takayoshi Ueno,
  • Harue Mizokami,
  • Yosuke Nakanishi and
  • Tomokazu Yoshizaki
  • + 4 authors

Semaphorins were discovered as guidance signals that mediate neural development. Recent studies suggest that semaphorin 3A (Sema3A), a member of the semaphorin family, is involved in the development of several cancers. This study aimed to analyze the...

  • Review
  • Open Access
425 Citations
26,506 Views
21 Pages

Quorum sensing is a cell-to-cell communication system that exists widely in the microbiome and is related to cell density. The high-density colony population can generate a sufficient number of small molecule signals, activate a variety of downstream...

  • Review
  • Open Access
49 Citations
8,174 Views
15 Pages

A Review and Perspective of eDNA Application to Eutrophication and HAB Control in Freshwater and Marine Ecosystems

  • Qi Liu,
  • Yun Zhang,
  • Han Wu,
  • Fengwen Liu,
  • Wei Peng,
  • Xiaonan Zhang,
  • Fengqin Chang,
  • Ping Xie and
  • Hucai Zhang

Changing ecological communities in response to anthropogenic activities and climate change has become a worldwide problem. The eutrophication of waterbodies in freshwater and seawater caused by the effects of human activities and nutrient inputs coul...

  • Article
  • Open Access
39 Citations
9,763 Views
11 Pages

Endotoxin (lipopolysaccharide) testing of drugs is routinely required in pharmaceutical industries. Suitable compendial assays are defined by national pharmacopoeias. At this time, Limulus Amoebocyte Lysate (LAL) assays are the gold standard. LAL is...

  • Article
  • Open Access
26 Citations
8,922 Views
17 Pages

Epstein–Barr Virus Infection of Oral Squamous Cells

  • Chukkris Heawchaiyaphum,
  • Hisashi Iizasa,
  • Tipaya Ekalaksananan,
  • Ati Burassakarn,
  • Tohru Kiyono,
  • Yuichi Kanehiro,
  • Hironori Yoshiyama and
  • Chamsai Pientong

The Epstein–Barr virus (EBV) is a human herpesvirus associated with various cancers. The number of reports that describe infection of EBV in oral squamous carcinoma cells is increasing. However, there is no available in vitro model to study the...

  • Article
  • Open Access
19 Citations
4,251 Views
22 Pages

Extensive Therapeutic Drug Monitoring of Colistin in Critically Ill Patients Reveals Undetected Risks

  • Stefan Felix Ehrentraut,
  • Stefan Muenster,
  • Stefan Kreyer,
  • Nils Ulrich Theuerkauf,
  • Christian Bode,
  • Folkert Steinhagen,
  • Heidi Ehrentraut,
  • Jens-Christian Schewe,
  • Matthias Weber and
  • Thomas Muders
  • + 1 author

(1) Background: With the rise of multi-/pan-drug resistant (MDR/PDR) pathogens, the less utilized antibiotic Colistin has made a comeback. Colistin fell out of favor due to its small therapeutic range and high potential for toxicity. Today, it is use...

  • Article
  • Open Access
22 Citations
5,484 Views
18 Pages

There is No Distinctive Gut Microbiota Signature in the Metabolic Syndrome: Contribution of Cardiovascular Disease Risk Factors and Associated Medication

  • Adrián Cortés-Martín,
  • Carlos E. Iglesias-Aguirre,
  • Amparo Meoro,
  • María Victoria Selma and
  • Juan Carlos Espín

The gut microbiota (GM) has attracted attention as a new target to combat several diseases, including metabolic syndrome (MetS), a pathological condition with many factors (diabetes, obesity, dyslipidemia, hypertension, etc.) that increase cardiovasc...

  • Article
  • Open Access
16 Citations
5,676 Views
15 Pages

Proteomic Adaptation of Streptococcus pneumoniae to the Human Antimicrobial Peptide LL-37

  • Pierre-Alexander Mücke,
  • Sandra Maaß,
  • Thomas P. Kohler,
  • Sven Hammerschmidt and
  • Dörte Becher

Secreted antimicrobial peptides (AMPs) are an important part of the human innate immune system and prevent local and systemic infections by inhibiting bacterial growth in a concentration-dependent manner. In the respiratory tract, the cationic peptid...

  • Article
  • Open Access
39 Citations
4,860 Views
15 Pages

Plant Growth Promotion Abilities of Phylogenetically Diverse Mesorhizobium Strains: Effect in the Root Colonization and Development of Tomato Seedlings

  • Esther Menéndez,
  • Juan Pérez-Yépez,
  • Mercedes Hernández,
  • Ana Rodríguez-Pérez,
  • Encarna Velázquez and
  • Milagros León-Barrios

Mesorhizobium contains species widely known as nitrogen-fixing bacteria with legumes, but their ability to promote the growth of non-legumes has been poorly studied. Here, we analyzed the production of indole acetic acid (IAA), siderophores and the s...

  • Article
  • Open Access
8 Citations
3,652 Views
11 Pages

Contamination Pathways can Be Traced along the Poultry Processing Chain by Whole Genome Sequencing of Listeria innocua

  • Mayada Gwida,
  • Stefanie Lüth,
  • Maged El-Ashker,
  • Amira Zakaria,
  • Fatma El-Gohary,
  • Mona Elsayed,
  • Sylvia Kleta and
  • Sascha Al Dahouk

Foodborne infection with Listeria causes potentially life-threatening disease listeriosis. Listeria monocytogenes is widely recognized as the only species of public health concern, and the closely related species Listeria innocua is commonly used by...

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Microorganisms - ISSN 2076-2607