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Pathogens, Volume 8, Issue 4

December 2019 - 144 articles

Cover Story: Leukotoxin is an important and powerful tool expressed by the periodontal pathogen, Aggregatibacter actinomycetemcomitans. The high leukotoxic potential of the virulent JP2 genotype of A. actinomycetemcomitans has been studied extensively. In order to obtain a comprehensive understanding of the leukotoxic potential of different genotypes of A. actinomycetemcomitans serotype b, a geographically widespread collection of strains has been analyzed by several methods. The present study of the leukotoxic potential of both the JP2 and non-JP2 genotype strains of A.actinomycetemcomitans emphasizes the importance of using more than one method when assessing the leukotoxin-related virulence capacity of A. actinomycetemcomitans. View this paper
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Articles (144)

  • Article
  • Open Access
23 Citations
4,556 Views
13 Pages

Genetic Basis and Physiological Effects of Lipid A Hydroxylation in Pseudomonas aeruginosa PAO1

  • Alessandra Lo Sciuto,
  • Matteo Cervoni,
  • Roberta Stefanelli,
  • Maria Concetta Spinnato,
  • Alessandra Di Giamberardino,
  • Carmine Mancone and
  • Francesco Imperi

10 December 2019

Modifications of the lipid A moiety of lipopolysaccharide influence the physicochemical properties of the outer membrane of Gram-negative bacteria. Some bacteria produce lipid A with a single hydroxylated secondary acyl chain. This hydroxylation is c...

  • Article
  • Open Access
19 Citations
4,902 Views
18 Pages

Tuberculosis Epidemiology and Badger (Meles meles) Spatial Ecology in a Hot-Spot Area in Atlantic Spain

  • Pelayo Acevedo,
  • Miguel Prieto,
  • Pablo Quirós,
  • Isabel Merediz,
  • Lucía de Juan,
  • José Antonio Infantes-Lorenzo,
  • Roxana Triguero-Ocaña and
  • Ana Balseiro

10 December 2019

We provide a temporal overview (from 2012 to 2018) of the outcomes of tuberculosis (TB) in the cattle and badger populations in a hot-spot in Asturias (Atlantic Spain). We also study the badger’s spatial ecology from an epidemiological perspect...

  • Article
  • Open Access
3 Citations
3,411 Views
9 Pages

The Impact of SsPI-1 Deletion on Streptococcus suis Virulence

  • Yan Zhao,
  • Gang Li,
  • Xin-Yue Yao,
  • Shu-Guang Lu,
  • Jing Wang,
  • Xiao-Dong Shen and
  • Ming Li

6 December 2019

(1) Background: Streptococcus suis is an important zoonotic pathogen that infects pigs and can occasionally cause life-threatening systemic infections in humans. Two large-scale outbreaks of streptococcal toxic shock-like syndrome in China suggest th...

  • Article
  • Open Access
15 Citations
4,651 Views
18 Pages

Surfactant Protein A Impairs Genital HPV16 Pseudovirus Infection by Innate Immune Cell Activation in A Murine Model

  • Sylvia Ujma,
  • Sinead Carse,
  • Alisha Chetty,
  • William Horsnell,
  • Howard Clark,
  • Jens Madsen,
  • Rose-Marie Mackay,
  • Alastair Watson,
  • Mark Griffiths and
  • Arieh A. Katz
  • + 1 author

6 December 2019

Infection by oncogenic human papillomavirus (HPV) is the principle cause of cervical cancer and other anogenital cancers. The majority of cervical cancer cases occur in low- and middle-income countries (LMIC). Prophylactic vaccines exist to combat HP...

  • Article
  • Open Access
10 Citations
4,244 Views
10 Pages

6 December 2019

The present study aimed to detect and characterize Borrelia spp. in ticks attached to dogs in Korea. Overall, 562 ticks (276 pools) attached to dogs were collected and tested for Borrelia infection by PCR targeting the 5S-23S rRNA intergenic spacer r...

  • Article
  • Open Access
7 Citations
4,799 Views
13 Pages

5 December 2019

Shipping of serum samples that were taken from pigs infected with classical swine fever (CSF) virus is frequently requested with the objective of serological analyses, not only for diagnostic purposes but also for exchange of reference materials that...

  • Review
  • Open Access
18 Citations
5,628 Views
10 Pages

4 December 2019

Multidrug-resistant (MDR) bacterial infections are a leading cause of mortality, affecting approximately 250,000 people in Canada and over 2 million people in the United States, annually. The lack of efficacy of antibiotic-based treatments is often c...

  • Article
  • Open Access
9 Citations
4,409 Views
18 Pages

Phenotypic Characterization of Rhodococcus equi Biofilm Grown In Vitro and Inhibiting and Dissolving Activity of Azithromycin/Rifampicin Treatment

  • Elisa Rampacci,
  • Maria Luisa Marenzoni,
  • Stefano Giovagnoli,
  • Fabrizio Passamonti,
  • Mauro Coletti and
  • Donatella Pietrella

4 December 2019

Microbial biofilm has been implicated in a wide range of chronic infections. In spite of the fact that Rhodococcus equi is a recognized cause of chronic disease in animals and humans, few studies have focused on the sessile phenotype of R. equi. The...

  • Article
  • Open Access
27 Citations
6,134 Views
18 Pages

4 December 2019

This study contributes new knowledge on the diversity of conidial fungi in edible pine (Pinus armandii) seeds found in Yunnan Province, China and emphasizes the importance of edible seed products to ensure food safety standards. We isolated two funga...

  • Article
  • Open Access
5 Citations
3,628 Views
13 Pages

Transcriptomic Analysis of Aggregatibacter actinomycetemcomitans Core and Accessory Genes in Different Growth Conditions

  • Natalia O. Tjokro,
  • Weerayuth Kittichotirat,
  • Annamari Torittu,
  • Riikka Ihalin,
  • Roger E. Bumgarner and
  • Casey Chen

3 December 2019

Aggregatibacter actinomycetemcomitans genome can be divided into an accessory gene pool (found in some but not all strains) and a core gene pool (found in all strains). The functions of the accessory genes (genomic islands and non-island accessory ge...

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Pathogens - ISSN 2076-0817