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Diagnostics, Volume 12, Issue 8

August 2022 - 257 articles

Cover Story: Increasing evidence shows the benefit of near-infrared fluorescence optical imaging (FOI, Xiralite™) for the diagnosis of rheumatoid arthritis, psoriatic arthritis, and osteoarthritis, among others. FOI visualizes impaired microcirculation of the hands, which in most cases leads to an increased accumulation of the contrast agent ICG in the affected regions, indicative of inflammation. This work summarizes the important image features, i.e., location, shape, and timing, found in patients with various rheumatic diseases. Enhancement patterns of patients’ FOI examinations are characterized and assigned to inflammatory anatomical structures, known to be typical for the respective diseases, in their clinical diagnoses. View this paper
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Articles (257)

  • Article
  • Open Access
23 Citations
3,318 Views
23 Pages

The trade-off between speed and precision is a key step in the detection of small polyps in wireless capsule endoscopy (WCE) images. In this paper, we propose a hybrid network of an inception v4 architecture-based single-shot multibox detector (Hyb-S...

  • Review
  • Open Access
14 Citations
14,560 Views
11 Pages

Cracked teeth can pose a diagnostic dilemma for a clinician as they can mimic several other conditions. The constant physiological stress along with any pathological strain like trauma or iatrogenic causes can lead to the development of microcracks i...

  • Article
  • Open Access
6 Citations
2,433 Views
12 Pages

Patients with obstructive hypertrophic cardiomyopathy (HOCM) have large papillary and trabecular muscles (PTMs), which are myocardial tissue. PTMs are usually excluded from the myocardium and included in the left ventricular (LV) cavity when determin...

  • Article
  • Open Access
22 Citations
4,379 Views
16 Pages

Interstitial Lung Fibrosis Following COVID-19 Pneumonia

  • Mihai Lazar,
  • Ecaterina Constanta Barbu,
  • Cristina Emilia Chitu,
  • Catalin Tiliscan,
  • Laurentiu Stratan,
  • Sorin Stefan Arama,
  • Victoria Arama and
  • Daniela Adriana Ion

Background and Objectives: Pulmonary fibrosis represents a stage of normal physiologic response to inflammatory aggression, mostly self-limiting and reversible; however, numerous patients treated for SARS-CoV-2 pneumonia present after release from ho...

  • Article
  • Open Access
5 Citations
2,337 Views
11 Pages

Detection of Autoantibodies in Saliva as New Avenue for the Diagnosis and Management of Autoimmune Patients

  • Savino Sciascia,
  • Chelsea Bentow,
  • Massimo Radin,
  • Alice Barinotti,
  • Irene Cecchi,
  • Silvia Foddai,
  • Dario Roccatello and
  • Michael Mahler

(1) Background: Autoimmune diseases are characterized by autoantibodies directed to a large number of antigenic targets and are measured using serum as sample matrix. Although serum is a very common specimen type, it comes with certain drawbacks. Mos...

  • Review
  • Open Access
10 Citations
8,121 Views
13 Pages

The Management of Pregnancy Complicated with the Previable Preterm and Preterm Premature Rupture of the Membranes: What about a Limit of Neonatal Viability?—A Review

  • Stepan Feduniw,
  • Zuzanna Gaca,
  • Olga Malinowska,
  • Weronika Brunets,
  • Magdalena Zgliczyńska,
  • Marta Włodarczyk,
  • Anna Wójcikiewicz and
  • Michał Ciebiera

Preterm premature rupture of the membranes (PPROM) at the limit of viability is associated with low neonatal survival rates and a high rate of neonatal complications in survivors. It carries a major risk of maternal morbidity and mortality. The limit...

  • Article
  • Open Access
5 Citations
4,069 Views
13 Pages

Postmortem Bacteriology in Forensic Autopsies—A Single Center Retrospective Study in Romania

  • Iuliana Diac,
  • Arthur-Atilla Keresztesi,
  • Anda-Mihaela Cerghizan,
  • Mihai Negrea and
  • Cătălin Dogăroiu

Postmortem bacteriology examinations have been a controversial topic over the years, though the value of postmortem bacteriology cultures remains promising. The aim of this study was to review the postmortem bacteriological sampling procedures and re...

  • Article
  • Open Access
4 Citations
2,603 Views
15 Pages

Advancing Brain Metastases Detection in T1-Weighted Contrast-Enhanced 3D MRI Using Noisy Student-Based Training

  • Engin Dikici,
  • Xuan V. Nguyen,
  • Matthew Bigelow,
  • John L. Ryu and
  • Luciano M. Prevedello

The detection of brain metastases (BM) in their early stages could have a positive impact on the outcome of cancer patients. The authors previously developed a framework for detecting small BM (with diameters of <15 mm) in T1-weighted contrast-enh...

  • Article
  • Open Access
4 Citations
3,747 Views
14 Pages

Assessment of Pulpal Status in Primary Teeth Following Direct Pulp Capping in an Experimental Canine Model

  • Andreea Igna,
  • Cornel Igna,
  • Mariana Ioana Miron,
  • Larisa Schuszler,
  • Roxana Dascălu,
  • Mihaela Moldovan,
  • Adrian Aristide Voicu,
  • Carmen Darinca Todea,
  • Marius Boariu and
  • Maria-Alexandra Mârțu
  • + 1 author

(1) Background: This study aimed to assess the pulpal response of primary teeth by pulse-oximetry (PO) in a canine model, following direct pulp capping (DPC). (2) Methods: Forty-eight primary teeth from eight canine subjects were divided into three t...

  • Article
  • Open Access
24 Citations
5,793 Views
9 Pages

Cell Toxicity Study of Antiseptic Solutions Containing Povidone–Iodine and Hydrogen Peroxide

  • Veronica Romano,
  • Donato Di Gennaro,
  • Anna Maria Sacco,
  • Enrico Festa,
  • Emanuela Roscetto,
  • Morena Anna Basso,
  • Tiziana Ascione and
  • Giovanni Balato

The increasing incidence of periprosthetic joint infections (PJIs) has led to a growing interest in developing strategies to prevent and treat this severe complication. The surgical site’s application of antiseptic solutions to eliminate contam...

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Diagnostics - ISSN 2075-4418