You are currently viewing a new version of our website. To view the old version click .

Genes, Volume 11, Issue 1

January 2020 - 115 articles

Cover Story: Astronaut Dr. Peggy Whitson turns the maintenance work area (MWA, blue surface) into a research bench aboard the International Space Station (ISS). Enabled by the miniPCR (Amplyus) and the MinION (Oxford Nanopore Technologies), pictured side-by-side on the MWA, Whitson prepared and sequenced DNA from bacteria collected from, and cultured aboard, the ISS. The agar slide used for bacterial culture was returned to the ground for standard laboratory processing and identification. The identifications obtained aboard the ISS matched those determined on the ground down to the species level, marking the first ever identification of microbes entirely off Earth. View this paper.
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (115)

  • Article
  • Open Access
16 Citations
4,488 Views
16 Pages

Expression Analysis of XTH in Stem Swelling of Stem Mustard and Selection of Reference Genes

  • Mengyao Li,
  • Fangjie Xie,
  • Qi He,
  • Jie Li,
  • Jiali Liu,
  • Bo Sun,
  • Ya Luo,
  • Yong Zhang,
  • Qing Chen and
  • Fen Zhang
  • + 4 authors

20 January 2020

Accurate analysis of gene expression requires selection of appropriate reference genes. In this study, we report analysis of eight candidate reference genes (ACTIN, UBQ, EF-1α, UBC, IF-4α, TUB, PP2A, and HIS), which were screened from the...

  • Article
  • Open Access
10 Citations
5,856 Views
13 Pages

Contribution of Known Genetic Risk Variants to Dyslipidemias and Type 2 Diabetes in Mexico: A Population-Based Nationwide Study

  • Alicia Huerta-Chagoya,
  • Hortensia Moreno-Macías,
  • Magdalena Sevilla-González,
  • Rosario Rodríguez-Guillén,
  • María L. Ordóñez-Sánchez,
  • Donají Gómez-Velasco,
  • Liliana Muñóz-Hernández,
  • Yayoi Segura-Kato,
  • Olimpia Arellano-Campos and
  • Ivette Cruz-Bautista
  • + 2 authors

20 January 2020

Dyslipidemias are common risk factors for the development of chronic disorders including type 2 diabetes (T2D). Over 100 associated loci have been identified but few reports have evaluated the population attributable fraction captured by them in popu...

  • Article
  • Open Access
6 Citations
4,573 Views
12 Pages

20 January 2020

We sequenced the mitochondrial genome of six colonial volvocine algae, namely: Pandorina morum, Pandorina colemaniae, Volvulina compacta, Colemanosphaera angeleri, Colemanosphaera charkowiensi, and Yamagishiella unicocca. Previous studies have typica...

  • Article
  • Open Access
8 Citations
4,138 Views
16 Pages

19 January 2020

Immune response to infections has been shown to be mediated by genetic diversity in pattern recognition receptors, leading to disease tolerance or susceptibility. We elucidated naturally occurring variations within the bovine CD14 gene promoter in tr...

  • Review
  • Open Access
67 Citations
10,729 Views
25 Pages

Understanding the Relevance of DNA Methylation Changes in Immune Differentiation and Disease

  • Carlos de la Calle-Fabregat,
  • Octavio Morante-Palacios and
  • Esteban Ballestar

18 January 2020

Immune cells are one of the most complex and diverse systems in the human organism. Such diversity implies an intricate network of different cell types and interactions that are dependently interconnected. The processes by which different cell types...

  • Article
  • Open Access
4 Citations
4,790 Views
17 Pages

The Expression of Decidual Protein Induced by Progesterone (DEPP) Is Controlled by Three Distal Consensus Hypoxia Responsive Element (HRE) in Hypoxic Retinal Epithelial Cells

  • Katrin Klee,
  • Federica Storti,
  • Jordi Maggi,
  • Vyara Todorova,
  • Duygu Karademir,
  • Wolfgang Berger,
  • Marijana Samardzija and
  • Christian Grimm

18 January 2020

Hypoxia affects the development and/or progression of several retinopathies. Decidual protein induced by progesterone (DEPP) has been identified as a hypoxia-responsive gene that may be part of cellular pathways such as autophagy and connected to ret...

  • Article
  • Open Access
8 Citations
3,512 Views
12 Pages

High-Concentrate Feeding to Dairy Cows Induces Apoptosis via the NOD1/Caspase-8 Pathway in Mammary Epithelial Cells

  • Zain ul Aabdin,
  • Xiaoye Cheng,
  • Hongyu Dai,
  • Yan Wang,
  • Benazir Sahito,
  • Animesh Chandra Roy,
  • Meena Arif Memon and
  • Xiangzhen Shen

17 January 2020

(1) Background: The effects of a high-concentrate (HC) diet in inducing mammary epithelial cell apoptosis in dairy cows via the NOD1/Caspase-8 pathway have never been investigated before the current study. (2) Methods: Twelve Holstein Frisian cows at...

  • Review
  • Open Access
25 Citations
5,416 Views
11 Pages

17 January 2020

Next-generation sequencing has led to the recent discovery of several novel pancreatic cancer susceptibility genes. These genes include ataxia telangiectasia mutated (ATM), a serine/threonine kinase that is an integral component of DNA repair. Pathog...

  • Article
  • Open Access
9 Citations
5,034 Views
27 Pages

Population Genomics in Rhamdia quelen (Heptapteridae, Siluriformes) Reveals Deep Divergence and Adaptation in the Neotropical Region

  • Néstor Ríos,
  • Adrián Casanova,
  • Miguel Hermida,
  • Belén G. Pardo,
  • Paulino Martínez,
  • Carmen Bouza and
  • Graciela García

17 January 2020

Rhamdia quelen, a Neotropical fish with hybridization between highly divergent mitochondrial DNA (mtDNA) lineages, represents an interesting evolutionary model. Previous studies suggested that there might be demographic differences between coastal la...

  • Article
  • Open Access
13 Citations
4,801 Views
11 Pages

Mitochondrial DNA Haplotypes Influence Energy Metabolism across Chicken Transmitochondrial Cybrids

  • Minghua Kong,
  • Hai Xiang,
  • Jikun Wang,
  • Jian Liu,
  • Xiben Zhang and
  • Xingbo Zhao

16 January 2020

The association between mitochondrial DNA haplotype and productive performances has been widely reported in chicken breeds. However, there has not been physiological evidence of this seen previously. In this study, chicken transmitochondrial cells we...

of 12

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Genes - ISSN 2073-4425Creative Common CC BY license