Prospects in Transgenic Technology 2020
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Technologies and Resources for Genetics".
Deadline for manuscript submissions: closed (29 February 2020) | Viewed by 52604
Special Issue Editors
Interests: gene editing technologies; animal models of human genetic diseases; embryonic stem cells
Special Issue Information
Dear colleagues,
With the advent of gene editing technologies, the ability to manipulate genomes has become amenable to nearly all species. Gene modification protocols that lead to new ways of generating genetically engineered model systems are being developed at an exponential pace, with new techniques reported almost daily. With this technology, we may be able to easily generate models of diseases affecting both humans and other animals, increase food production worldwide, and perform gene therapy to alleviate disease, among the many possibilities. However, success should be based on an understanding of when to use newer vs. established technologies. Scientists should be aware of both expected and unexpected consequences of the particular method chosen for gene modification. Analyses and assessments that take into account such consequences are critical for acceptance by society, as is an ethical approach to determining what uses such technology can have.
This Special Issue of Genes welcomes original research manuscripts and review papers that address the science and ethics of gene modification. Topics of interest include, but are not limited to:
- New methods and protocols using gene editing technology;
- Research describing previously unforeseen caveats with gene modification;
- Gene modification research in unconventional animal models or exotic species;
- The use of gene editing to enhance agrarian species for food production;
- Gene editing used for gene therapy;
- Ethical considerations associated with gene modification, particularly in humans;
- How gene editing affects the 3Rs of animal use;
- Methods of public outreach and education used for gene modification acceptance.
Dr. Wojtek Auerbach
Dr. Jan Parker-Thornburg
Guest Editors
Manuscript Submission Information
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Keywords
- Gene editing technologies
- Gene modification
- Genome engineering
- Transgenic technology
- Models of disease
- Food production
- Gene therapy
- CRISPR-Cas9
- Nucleases
- Ethics
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