You are currently viewing a new version of our website. To view the old version click .

Cells, Volume 12, Issue 1

January-1 2023 - 203 articles

Cover Story: The gut microbiota plays an important role in maintaining the host’s health by delicately balancing commensal and pathogenic bacteria, thus influencing their metabolic, oxidative and cognitive status. Despite there being interindividual differences, it is known that the composition of the microbiota in the elderly differs significantly from that of young people. Even with an accumulation of new evidence regarding the efficacy of microbiota therapies, communicating this to the elderly is a difficult challenge. A detailed understanding of the actions of gut microorganisms is useful to delay the onset of age-related pathologies and to develop strategies which target individual needs. In this study, we discuss the effects of physical activity, dietary interventions and supplements as part of an integrated strategy to implement microbiota health with the goal of healthy aging. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (203)

  • Article
  • Open Access
12 Citations
3,426 Views
18 Pages

Synergism of Feeding and Digestion Regulated by the Neuropeptide F System in Ostrinia furnacalis Larvae

  • Jiajia Zhao,
  • Yu Song,
  • Xuemin Jiang,
  • Lei He,
  • Liya Wei and
  • Zhangwu Zhao

3 January 2023

Feeding is crucial for the growth and survival of animals, including humans, but relatively little is known about how it is regulated. Here, we show that larval feeding in Ostrinia furnacalis is regulated by neuropeptide F (NPF, the homologous peptid...

  • Article
  • Open Access
6 Citations
3,006 Views
10 Pages

Pervasive Platelet Secretion Defects in Patients with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

  • Johannes Kalbhenn,
  • Jan-Steffen Pooth,
  • Georg Trummer,
  • David Kranzhöfer,
  • Axel Schlagenhauf and
  • Barbara Zieger

3 January 2023

Critically ill COVID-19 patients suffer from thromboembolic as well as bleeding events. Endothelial dysfunction, spiking of von Willebrand factor (vWF), and excessive cytokine signaling result in coagulopathy associated with substantial activation of...

  • Review
  • Open Access
26 Citations
7,427 Views
22 Pages

3 January 2023

GBA gene variants were the first genetic risk factor for Parkinson’s disease. GBA encodes the lysosomal enzyme glucocerebrosidase (GBA), which is involved in sphingolipid metabolism. GBA exhibits a complex physiological function that includes n...

  • Systematic Review
  • Open Access
29 Citations
9,239 Views
22 Pages

Effect of Different Application Modalities on the Bonding Performance of Adhesive Systems to Dentin: A Systematic Review and Meta-Analysis

  • Louis Hardan,
  • Rim Bourgi,
  • Carlos Enrique Cuevas-Suárez,
  • Walter Devoto,
  • Maciej Zarow,
  • Paulo Monteiro,
  • Natalia Jakubowicz,
  • Amine El Zoghbi,
  • Dariusz Skaba and
  • Davide Mancino
  • + 3 authors

3 January 2023

Diverse types of dental adhesives exhibit different cytotoxic outcomes on cells in vitro. Currently, no standard adhesive application technique has so far been decisive for clinicians for better durability of resin–dentin bonds of adhesive syst...

  • Article
  • Open Access
10 Citations
3,064 Views
28 Pages

Maternal Hyperhomocysteinemia Disturbs the Mechanisms of Embryonic Brain Development and Its Maturation in Early Postnatal Ontogenesis

  • Dmitrii S. Vasilev,
  • Anastasiia D. Shcherbitskaia,
  • Natalia L. Tumanova,
  • Anastasiia V. Mikhel,
  • Yulia P. Milyutina,
  • Anna A. Kovalenko,
  • Nadezhda M. Dubrovskaya,
  • Daria B. Inozemtseva,
  • Irina V. Zalozniaia and
  • Alexander V. Arutjunyan

3 January 2023

Maternal hyperhomocysteinemia causes the disruption of placental blood flow and can lead to serious disturbances in the formation of the offspring’s brain. In the present study, the effects of prenatal hyperhomocysteinemia (PHHC) on the neurona...

  • Feature Paper
  • Article
  • Open Access
4 Citations
3,112 Views
17 Pages

Transcriptomic Analysis Reveals JAK2/MPL-Independent Effects of Calreticulin Mutations in a C. elegans Model

  • Ana Guijarro-Hernández,
  • Laura Eder-Azanza,
  • Cristina Hurtado,
  • David Navarro-Herrera,
  • Begoña Ezcurra,
  • Francisco Javier Novo,
  • Juan Cabello and
  • José Luis Vizmanos

2 January 2023

There is growing evidence that Ph-negative myeloproliferative neoplasms (MPNs) are disorders in which multiple molecular mechanisms are significantly disturbed. Since their discovery, CALR driver mutations have been demonstrated to trigger pathogenic...

  • Review
  • Open Access
56 Citations
10,370 Views
15 Pages

Multiple Roles of PLK1 in Mitosis and Meiosis

  • Jaroslav Kalous and
  • Daria Aleshkina

2 January 2023

Cells are equipped with a diverse network of signaling and regulatory proteins that function as cell cycle regulators and checkpoint proteins to ensure the proper progression of cell division. A key regulator of cell division is polo-like kinase 1 (P...

  • Feature Paper
  • Article
  • Open Access
30 Citations
4,029 Views
15 Pages

Azilsartan Modulates HMGB1/NF-κB/p38/ERK1/2/JNK and Apoptosis Pathways during Renal Ischemia Reperfusion Injury

  • Rania Alaaeldin,
  • Sally M. Bakkar,
  • Reham H. Mohyeldin,
  • Fares E. M. Ali,
  • Nehad M. Reda Abdel-Maqsoud and
  • Moustafa Fathy

2 January 2023

Renal ischemia/reperfusion (IR) injury is characterized by an unexpected impairment of blood flow to the kidney. Azilsartan is an angiotensin receptor blocker that is approved for the management of hypertension. The present study aimed to investigate...

  • Review
  • Open Access
600 Citations
46,339 Views
33 Pages

Probiotics Mechanism of Action on Immune Cells and Beneficial Effects on Human Health

  • Chiara Mazziotta,
  • Mauro Tognon,
  • Fernanda Martini,
  • Elena Torreggiani and
  • John Charles Rotondo

2 January 2023

Immune cells and commensal microbes in the human intestine constantly communicate with and react to each other in a stable environment in order to maintain healthy immune activities. Immune system-microbiota cross-talk relies on a complex network of...

of 21

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Cells - ISSN 2073-4409