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Nutrients, Volume 9, Issue 6

June 2017 - 109 articles

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Cover Story: Chronic overconsumption of sugar-sweetened beverages (SSBs) is amongst the dietary factors most consistently found to be associated with obesity, type 2 diabetes (T2D) and cardiovascular disease (CVD) risk in large epidemiological studies. Public health initiatives aimed specifically at decreasing SSB overconsumption will most likely be successful in influencing SSB consumption per se. However, comprehensive strategies targeting poor dietary patterns and aiming at improving global dietary quality are likely to have much more impact in addressing the unprecedented public health challenges that we are currently facing. View the paper

Articles (109)

  • Article
  • Open Access
59 Citations
8,801 Views
17 Pages

Glucose and Lipid Dysmetabolism in a Rat Model of Prediabetes Induced by a High-Sucrose Diet

  • Ana Burgeiro,
  • Manuela G. Cerqueira,
  • Bárbara M. Varela-Rodríguez,
  • Sara Nunes,
  • Paula Neto,
  • Frederico C. Pereira,
  • Flávio Reis and
  • Eugénia Carvalho

21 June 2017

Glucotoxicity and lipotoxicity are key features of type 2 diabetes mellitus, but their molecular nature during the early stages of the disease remains to be elucidated. We aimed to characterize glucose and lipid metabolism in insulin-target organs (l...

  • Article
  • Open Access
24 Citations
7,358 Views
20 Pages

Despite Inflammation, Supplemented Essential Amino Acids May Improve Circulating Levels of Albumin and Haemoglobin in Patients after Hip Fractures

  • Roberto Aquilani,
  • Ginetto Carlo Zuccarelli,
  • Anna Maria Condino,
  • Michele Catani,
  • Carla Rutili,
  • Consiglia Del Vecchio,
  • Pietro Pisano,
  • Manuela Verri,
  • Paolo Iadarola and
  • Simona Viglio
  • + 1 author

21 June 2017

Essential amino acids (EAAs) are nutritional substrates that promote body protein synthesis; thus we hypothesised that their supplementation may improve circulating albumin (Alb) and haemoglobin (Hb) in rehabilitative elderly patients following hip f...

  • Article
  • Open Access
32 Citations
6,533 Views
13 Pages

21 June 2017

Although vitamins play a major role in health, and their deficiency may be linked to symptoms of optic-nerve dysfunction, the association between serum vitamin levels and glaucoma in humans remains controversial. In this study, articles in the PubMed...

  • Article
  • Open Access
24 Citations
5,960 Views
16 Pages

20 June 2017

Medium-chain fatty acids (MCFA) are a directly and readily absorbed source of energy. Exposure early-in-life to increased MCFA levels might affect development and impact (lipid) metabolism later in life. We tested whether an increased MCFA intake ear...

  • Article
  • Open Access
84 Citations
16,520 Views
17 Pages

PREVIEW: Prevention of Diabetes through Lifestyle Intervention and Population Studies in Europe and around the World. Design, Methods, and Baseline Participant Description of an Adult Cohort Enrolled into a Three-Year Randomised Clinical Trial

  • Mikael Fogelholm,
  • Thomas Meinert Larsen,
  • Margriet Westerterp-Plantenga,
  • Ian Macdonald,
  • J. Alfredo Martinez,
  • Nadka Boyadjieva,
  • Sally Poppitt,
  • Wolfgang Schlicht,
  • Gareth Stratton and
  • Jouko Sundvall
  • + 13 authors

20 June 2017

Type-2 diabetes (T2D) is one of the fastest growing chronic diseases worldwide. The PREVIEW project has been initiated to find the most effective lifestyle (diet and physical activity) for the prevention of T2D, in overweight and obese participants w...

  • Article
  • Open Access
63 Citations
18,395 Views
13 Pages

Spirulina Protects against Hepatic Inflammation in Aging: An Effect Related to the Modulation of the Gut Microbiota?

  • Audrey M. Neyrinck,
  • Bernard Taminiau,
  • Hannah Walgrave,
  • Georges Daube,
  • Patrice D. Cani,
  • Laure B. Bindels and
  • Nathalie M. Delzenne

20 June 2017

Aging predisposes to hepatic dysfunction and inflammation that can contribute to the development of non-alcoholic fatty liver disease. Spirulina, a cyanobacterium used as a food additive or food supplement, has been shown to impact immune function. W...

  • Review
  • Open Access
42 Citations
10,406 Views
23 Pages

Toxic AGE (TAGE) Theory for the Pathophysiology of the Onset/Progression of NAFLD and ALD

  • Masayoshi Takeuchi,
  • Jun-ichi Takino,
  • Akiko Sakasai-Sakai,
  • Takanobu Takata and
  • Mikihiro Tsutsumi

20 June 2017

Non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease (ALD) are among the most common causes of chronic liver diseases in the westernized world. NAFLD and ALD are frequently accompanied by extrahepatic complications, including hepatoc...

  • Article
  • Open Access
29 Citations
8,894 Views
11 Pages

Modulatory Effects of Guarana (Paullinia cupana) on Adipogenesis

  • Natália Da Silva Lima,
  • Erica De Paula Numata,
  • Leonardo Mendes de Souza Mesquita,
  • Pollyana Hammoud Dias,
  • Wagner Vilegas,
  • Alessandra Gambero and
  • Marcelo Lima Ribeiro

20 June 2017

Guarana (Paullinia cupana) is a plant originated in Brazil that presents a beneficial effect on body weight control and metabolic alterations. The aim of this study was to evaluate the effects of guarana on genes and miRNAs related to adipogenesis in...

  • Article
  • Open Access
17 Citations
8,170 Views
17 Pages

19 June 2017

A low Omega-3 Index (eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in erythrocytes) is associated with cardiac, cerebral, and other health issues. Intake of EPA and DHA, but not of alpha-linolenic acid (ALA), increases the Omega-3 Index....

  • Article
  • Open Access
37 Citations
7,890 Views
17 Pages

19 June 2017

We aimed to investigate the association between dairy product consumption and the risk of obesity and metabolic syndrome (MetS) in Korean adults. Data from 13,692 Korean adults aged ≥19 years from the KNHANES 2010–2013 were used. The study participan...

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