Special Issue "Nutrition and Non-alcoholic Fatty Liver Disease"
A special issue of Nutrients (ISSN 2072-6643).
Deadline for manuscript submissions: closed (15 July 2017) | Viewed by 124781
2. University "La Sapienza", Rome, Italy
Interests: fatty liver, metabolic syndrome, nutrients intake and gut-liver diseases
Interests: liver diseases; non-alcoholic fatty liver disease; hepatocellular carcinoma; epigenetic mechanisms; microRNAs
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We are experiencing a worldwide epidemic of obesity, which is associated with different comorbidities, such as non-alcoholic fatty liver disease (NAFLD), which is currently considered the most common hepatopathy worldwide.
The purpose of this Special Issue, “Nutrition and Non-alcoholic Fatty Liver Disease”, is to provide an overview of the role of different nutrients and dietary models on the development, treatment, prevention, and reversal of NAFLD. A high-calorie diet, particularly rich in saturated fatty acids and cholesterol, sugary drinks with high fructose content, increases visceral adiposity inducing the accumulation of lipids in the hepatocytes and triggers other systemic and tissue specific responses driving the progression of liver damage. These events could be exacerbated by a genetic predisposition. In this context, the reduction of caloric intake, obtained with lifestyle interventions or with dietary supplements (i.e., omega-3 fatty acids, vitamins, probiotics) may contribute to reverse metabolic derangement and liver damage occurring in NAFLD.
The topics covered should include: i) epidemiology of NAFLD and the role nutrition as risk factor; ii) the interaction of nutrition with genetics; iii) the role of breastfeeding; iv) the role of gut microbiota; and v) nutritional programs that can be used to treat or prevent NAFLD; omics approaches to study nutrigenomics in NAFLD.
Prof. Valerio Nobili
Dr. Anna Alisi
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- Non-alcoholic fatty liver disease
- Caloric intake
- Gene Variants
- Gut Microbiota
- Omega-3 fatty acids
- Experimental Models