Nutrients, Volume 18, Issue 1
2026 January-1 - 179 articles
Cover Story: Obesity is a chronic, relapsing disease and a major public health challenge worldwide. Effective weight loss requires a sustained negative energy balance, but its achievement is influenced by multiple interacting factors. This narrative review synthesizes evidence on nutritional interventions in obesity, mechanisms and modifiable factors influencing weight loss, and characteristics of individuals who successfully maintain long-term weight loss outcomes. The review discusses dietary approaches, psychological and physiological barriers, physical activity, and sleep as factors shaping both weight loss and its maintenance. Together, these findings aim to support practical, individualized, and evidence-based strategies for clinicians working with people living with obesity as well as for individuals themselves. View this paper - Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
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