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Nutrients, Volume 18, Issue 1

2026 January-1 - 179 articles

Cover Story: Obesity is a chronic, relapsing disease and a major public health challenge worldwide. Effective weight loss requires a sustained negative energy balance, but its achievement is influenced by multiple interacting factors. This narrative review synthesizes evidence on nutritional interventions in obesity, mechanisms and modifiable factors influencing weight loss, and characteristics of individuals who successfully maintain long-term weight loss outcomes. The review discusses dietary approaches, psychological and physiological barriers, physical activity, and sleep as factors shaping both weight loss and its maintenance. Together, these findings aim to support practical, individualized, and evidence-based strategies for clinicians working with people living with obesity as well as for individuals themselves. View this paper
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Articles (179)

  • Article
  • Open Access
422 Views
15 Pages

Physical Activity Determinants Under the Double Burden of Malnutrition: Contrasting Pathways for Underweight and Overweight Chinese Adolescents

  • Liying Yao,
  • Shuaishuai Jia,
  • Xiaochang Lv,
  • Yongguan Dai,
  • Yee Cheng Kueh,
  • Jinfu Xu,
  • Jianqiu Cong and
  • Garry Kuan

5 January 2026

Background: Chinese adolescents face a dual burden of malnutrition, yet the weight-status-specific mechanisms underlying physical activity (PA) participation remain underexplored. Methods: We conducted a cross-sectional study among 1573 adolescents (...

  • Article
  • Open Access
627 Views
16 Pages

Low-Carbohydrate Diet and Metabolic Syndrome Risk in Korean Adults: A Korea National Health and Nutrition Examination Survey Study

  • Vasuki Rajaguru,
  • Jeoungmi Kim,
  • Durga Datta Chapagain,
  • Tae Hyun Kim,
  • Sang Gyu Lee and
  • Whiejong M. Han

5 January 2026

Aims: Low-carbohydrate diets (LCDs) are associated with metabolic benefits, but their long-term effects remain uncertain, particularly in Asian populations with traditionally high carbohydrate intake. This study examined LCD patterns and their associ...

  • Article
  • Open Access
581 Views
20 Pages

5 January 2026

Background/Objectives: Food cravings are common with high-palatability foods that are high in sugar and/or fat. Food cues can strongly induce food craving, and heightened food cue reactivity is associated with eating disorders and obesity. Sweet tast...

  • Article
  • Open Access
619 Views
20 Pages

Salmon Nasal Cartilage Proteoglycan Ameliorate Joint Pain and Cartilage Degradation by Regulating Catabolic and Anabolic Homeostasis in MIA-Induced Osteoarthritis

  • Min Yu,
  • So Eun Jo,
  • Young Bae Son,
  • Ye Jin Kim,
  • Youngsik Seo,
  • Sang Bae Han,
  • Hyun Jin Kim,
  • Seon Gil Do,
  • Hanjoong Jo and
  • Dong Ju Son

5 January 2026

Background/Objectives: Osteoarthritis (OA) is a pervasive chronic joint disease characterized by the triad of persistent articular cartilage degeneration, debilitating synovial inflammation, and sustained chronic pain. Although salmon nasal cartilage...

  • Article
  • Open Access
948 Views
26 Pages

Multi-Strain Probiotic Improves Tryptophan Metabolism and Symptoms in Chronic Fatigue Syndrome Patients with Co-Occurring Irritable Bowel Syndrome: An Open-Label Pilot Study

  • Cezary Chojnacki,
  • Marta Mędrek-Socha,
  • Jan Chojnacki,
  • Anita Gąsiorowska,
  • Ewa Walecka-Kapica,
  • Michal Bijak,
  • Karolina Przybylowska-Sygut and
  • Tomasz Poplawski

5 January 2026

Background/Objectives: Gut dysbiosis in Chronic Fatigue Syndrome (CFS) drives low-grade inflammation and shifts tryptophan metabolism toward neurotoxic pathways. The causal link between bacterial translocation, kynurenine pathway dysregulation, and s...

  • Article
  • Open Access
848 Views
13 Pages

5 January 2026

Background/Objectives: Vitamin D plays an important role in muscle metabolism and recovery, yet its kinetics during and after football-specific physical activity remain poorly understood. Therefore, this study aimed to determine whether physical effo...

  • Systematic Review
  • Open Access
824 Views
30 Pages

The Role of Omega-3 Polyunsaturated Fatty Acid Supplementation in Postoperative Recovery of Colorectal Cancer: Systematic Review and Meta-Analysis

  • Huzhong Li,
  • Zhenze Xu,
  • Yamin Chen,
  • Jianming Guo,
  • Qihe Wang,
  • Dong Liang,
  • Pengfeng Qu,
  • Taotao Deng,
  • Yuan Yuan and
  • Ziyuan Wang
  • + 2 authors

5 January 2026

Background: China is currently developing standards for Food for Special Medical Purposes (FSMP) targeting for oncology patients. However, substantial challenges remain in defining optimal fortification levels of omega-3 polyunsaturated fatty acids (...

  • Reply
  • Open Access
364 Views
2 Pages
  • Article
  • Open Access
573 Views
23 Pages

An Acebuche Oil-Enriched Diet Prevents Early-Stage Cerebrovascular Alterations in the 5xFAD Mouse Model of Alzheimer’s Disease

  • Lorenzo Guidotti,
  • Dominga Lapi,
  • Martina Lucchesi,
  • Silvia Valori,
  • Francesca Corsi,
  • Lucia Giambastiani,
  • Andrea Vornoli,
  • Claudia Gargini,
  • Maurizio Cammalleri and
  • Massimo Dal Monte

5 January 2026

Background/Objectives: Alzheimer’s disease (AD) is a neurodegenerative disorder in which altered microvascular circulation participates in the pathogenesis. The lack of therapeutic treatments for AD makes the development of strategies aimed at...

  • Comment
  • Open Access
1 Citations
528 Views
2 Pages

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Nutrients - ISSN 2072-6643