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Nutrients, Volume 15, Issue 13

July-1 2023 - 255 articles

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Cover Story: Prolonged fatigue is associated with non-pathological causes and lacks an established therapeutic approach. The current study is aimed at assessing the efficacy of a new food supplement (Improve™) based on a chemically characterized pomegranate extract and hydro-soluble vitamins (B complex and C). UHPLC-HRMS analysis of pomegranate extract showed the presence of 59 compounds, with gallotannins and ellagitannins being the most abundant phytochemicals. For the clinical study, 58 subjects were randomized into two groups, 1 and 2 (n = 29, each), which received either the food supplement or placebo. View this paper

Articles (255)

  • Article
  • Open Access
11 Citations
14,476 Views
17 Pages

Pharmacokinetic Analyses of Liposomal and Non-Liposomal Multivitamin/Mineral Formulations

  • Joungbo Ko,
  • Choongsung Yoo,
  • Dante Xing,
  • Drew E. Gonzalez,
  • Victoria Jenkins,
  • Broderick Dickerson,
  • Megan Leonard,
  • Kay Nottingham,
  • Jacob Kendra and
  • Ryan Sowinski
  • + 2 authors

7 July 2023

Recent research supports previous contentions that encapsulating vitamins and minerals with liposomes help improve overall bioavailability. This study examined whether ingesting a liposomal multivitamin and mineral supplement (MVM) differentially aff...

  • Article
  • Open Access
2 Citations
3,550 Views
11 Pages

7 July 2023

The dietary acid load (DAL) is a novel marker of overall diet quality, which has been associated with overweight, type 2 diabetes and altered glucocorticoid secretion. A potential association with sex hormones is thus not inconceivable. We investigat...

  • Article
  • Open Access
8 Citations
3,846 Views
11 Pages

7 July 2023

Obesity is a global health problem that affects the quality of life. It is a multidimensional chronic risk factor for major medical conditions, such as cardiovascular diseases, diabetes, and cancer. This clinical trial evaluated the efficacy of Lacto...

  • Systematic Review
  • Open Access
5 Citations
4,839 Views
33 Pages

Does Native Vitamin D Supplementation Have Pleiotropic Effects in Patients with End-Stage Kidney Disease? A Systematic Review of Randomized Trials

  • Nathan G. Pilkey,
  • Olivia Novosel,
  • Angélique Roy,
  • Tristin E. Wilson,
  • Jaya Sharma,
  • Sono Khan,
  • Sanjana Kapuria,
  • Michael A. Adams and
  • Rachel M. Holden

7 July 2023

Vitamin D has been shown to have multiple pleiotropic effects beyond bone and mineral metabolism, with purported roles in cardiovascular disease, cancer, and host immunity. Vitamin D deficiency is common in patients with end-stage kidney disease (ESK...

  • Systematic Review
  • Open Access
12 Citations
7,708 Views
41 Pages

7 July 2023

Nutritional deficiencies during pregnancy can have serious consequences for the health of the (unborn) child. This systematic review provides an updated overview of the available food and nutrient intake data for pregnant women in The Netherlands and...

  • Review
  • Open Access
19 Citations
6,310 Views
19 Pages

Effects of Unconventional Work and Shift Work on the Human Gut Microbiota and the Potential of Probiotics to Restore Dysbiosis

  • Aroa Lopez-Santamarina,
  • Alicia del Carmen Mondragon,
  • Alejandra Cardelle-Cobas,
  • Eva Maria Santos,
  • Jose Julio Porto-Arias,
  • Alberto Cepeda and
  • Jose Manuel Miranda

7 July 2023

The work environment is a factor that can significantly influence the composition and functionality of the gut microbiota of workers, in many cases leading to gut dysbiosis that will result in serious health problems. The aim of this paper was to pro...

  • Article
  • Open Access
3 Citations
3,159 Views
17 Pages

Influence of 12-Week Concurrent Training on Exosome Cargo and Its Relationship with Cardiometabolic Health Parameters in Men with Obesity

  • Brisamar Estébanez,
  • Francisco J. Amaro-Gahete,
  • Cristina Gil-González,
  • Javier González-Gallego,
  • María J. Cuevas and
  • David Jiménez-Pavón

7 July 2023

Exosome release varies depending on the physiological state of the cell, so they could play a fundamental role in obesity, the biggest pandemic in today’s societies. The beneficial effects that physical activity has both on weight and cardiovas...

  • Protocol
  • Open Access
8 Citations
6,145 Views
17 Pages

Ketogenic-Mimicking Diet as a Therapeutic Modality for Bipolar Disorder: Biomechanistic Rationale and Protocol for a Pilot Clinical Trial

  • Jeffrey L. B. Bohnen,
  • Travis P. Wigstrom,
  • Alexis M. Griggs,
  • Stiven Roytman,
  • Noah Paalanen,
  • Hailemicael A. Andrews,
  • Nicolaas I. Bohnen,
  • Jacob J. H. Franklin and
  • Melvin G. McInnis

7 July 2023

There is growing interest in the investigation of ketogenic diets as a potential therapy for bipolar disorder. The overlapping pharmacotherapies utilized for both bipolar disorder and seizures suggest that a mechanistic overlap may exist between thes...

  • Article
  • Open Access
5 Citations
2,709 Views
12 Pages

Sex-Specific Differences in Left Ventricular Mass and Volumes with Body Mass Index among Children Aged 6 to 8: A Cross-Sectional Study in China

  • Huidi Xiao,
  • Wen Shu,
  • Menglong Li,
  • Liyuan Xu,
  • Nubiya Amaerjiang,
  • Jiawulan Zunong,
  • Sten H. Vermund,
  • Dayong Huang,
  • Mei Chong and
  • Yifei Hu

7 July 2023

Few studies have examined the sex differences in left ventricle (LV) structure and physiology from early life stages. We aimed to assess the role of sex and overweight/obesity on left ventricular mass (LVM) and LV volume in Chinese children without p...

  • Article
  • Open Access
2 Citations
1,600 Views
11 Pages

25OHVitamin D Levels in a Canarian Pediatric Population with and without Type 1 Diabetes: The Role of Acidosis

  • Yeray Nóvoa-Medina,
  • Marta Barreiro-Bautista,
  • Marta Perdomo-Quinteiro,
  • Jesús María González-Martín,
  • Sofía Quinteiro-González,
  • Ángela Domínguez,
  • María Cabrera,
  • Sara López,
  • Svetlana Pavlovic and
  • Ana M. Wägner

7 July 2023

The role of Vitamin D in the development of type 1 diabetes (T1D) is controversial. The Canary Islands have the highest incidence of childhood-onset T1D in Spain and one of the highest in Europe. We aimed to evaluate 25OHVitamin D concentrations in a...

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