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Nutrients, Volume 12, Issue 11

November 2020 - 376 articles

Cover Story: The composition and functioning of the gut microbiota, the complex population of microorganisms residing in the intestine, is strongly affected by endogenous and exogenous factors, among which diet is key. Important perturbations of the microbiota have been observed to contribute to disease risk, as in the case of neurological disorders, inflammatory bowel disease, obesity, diabetes, cardiovascular disease, among others. Due to the role of diet in the modulation of the microbiota, its composition is of high interest in inherited errors of metabolism (IEMs) and may reveal an appealing therapeutic target. In IEMs, for example in phenylketonuria (PKU), since part of the therapeutic intervention is based on chronic or life-long tailored dietetic regimens, important variations of the microbial diversity or relative abundance have been observed. View this paper
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Articles (376)

  • Article
  • Open Access
18 Citations
4,761 Views
13 Pages

Allyl Isothiocyanate Protects Acetaminophen-Induced Liver Injury via NRF2 Activation by Decreasing Spontaneous Degradation in Hepatocyte

  • Min Woo Kim,
  • Ju-Hee Kang,
  • Hyun Jin Jung,
  • Se Yong Park,
  • Thu Han Le Phan,
  • Hee Namgung,
  • Seung-Yong Seo,
  • Yeo Sung Yoon and
  • Seung Hyun Oh

23 November 2020

Acetaminophen (APAP) is one of the most frequently prescribed analgesic and anti-pyretic drugs. However, APAP-induced hepatotoxicity is a major cause of acute liver failure globally. While the therapeutic dose is safe, an overdose of APAP produces an...

  • Article
  • Open Access
24 Citations
6,654 Views
16 Pages

23 November 2020

A vegetarian diet has been associated with a lower risk of coronary artery disease (CAD). Plasma triacylglycerols, ceramides, and phosphatidylcholines may improve prediction of recurrent coronary events. We sought to investigate effects of a lacto-ov...

  • Article
  • Open Access
7 Citations
4,990 Views
15 Pages

Influence of Fermented Red Clover Extract on Skeletal Muscle in Early Postmenopausal Women: A Double-Blinded Cross-Over Study

  • Mikkel Oxfeldt,
  • Line Barner Dalgaard,
  • Jeyanthini Risikesan,
  • Frank Ted Johansen and
  • Mette Hansen

23 November 2020

Objective: To investigate effects of supplementation with a fermented red clover (RC) extract on signaling proteins related to muscle protein synthesis and breakdown at rest and in response to a resistance exercise bout. Methods: Ten postmenopausal w...

  • Article
  • Open Access
74 Citations
5,924 Views
16 Pages

23 November 2020

Recent studies continue to demonstrate the potential of edible insects as a protein base to obtain bioactive peptides applicable for functional food development. This study aimed at identifying antihypertensive, anti-glycemic, and anti-inflammatory p...

  • Article
  • Open Access
21 Citations
8,452 Views
30 Pages

Sex-Specific Effects of Chronic Creatine Supplementation on Hippocampal-Mediated Spatial Cognition in the 3xTg Mouse Model of Alzheimer’s Disease

  • Wanda M. Snow,
  • Chris Cadonic,
  • Claudia Cortes-Perez,
  • Aida Adlimoghaddam,
  • Subir K. Roy Chowdhury,
  • Ella Thomson,
  • Adama Anozie,
  • Michael J. Bernstein,
  • Kathleen Gough and
  • Paul Fernyhough
  • + 2 authors

23 November 2020

The creatine (Cr) energy system has been implicated in Alzheimer’s disease (AD), including reductions in brain phosphoCr and Cr kinase, yet no studies have examined the neurobehavioral effects of Cr supplementation in AD, including the 3xTg mou...

  • Article
  • Open Access
5 Citations
4,349 Views
14 Pages

23 November 2020

Nutrition is an essential part of oncology care; however, nutrition advice and guidance are not always provided. This six-week pilot pretest-posttest intervention was designed to test the feasibility and effectiveness of integrating a nutrition educa...

  • Article
  • Open Access
8 Citations
3,466 Views
13 Pages

23 November 2020

As a part of the salt controversy, it has been suggested that people with a low sodium intake have an increased risk of cardiovascular events. However, there is no clear explanation for this increased risk. We examined the socio-demographic, clinical...

  • Article
  • Open Access
1 Citations
3,479 Views
17 Pages

23 November 2020

This cross-sectional study compared weight-related cognitions, behaviors, and home environments of 568 mothers of young children (ages 2 to <9 years) by racial/ethnic group. Maternal health status was good and did not differ by race/ethnicity. Mot...

  • Article
  • Open Access
3 Citations
4,385 Views
11 Pages

Childhood Malnutrition and Association of Lean Mass with Metabolome and Hormone Profile in Later Life

  • Gerard Bryan Gonzales,
  • Natasha Lelijveld,
  • Celine Bourdon,
  • Emmanuel Chimwezi,
  • Moffat J. Nyirenda,
  • Jonathan C. Wells,
  • Marko Kerac and
  • Robert H. J. Bandsma

23 November 2020

This study aimed to determine the associations of targeted metabolomics and hormone profiles data with lean mass index (LMI), which were estimated using bioelectrical impedance, in survivors of child severe malnutrition (SM) (n = 69) and controls (n...

  • Article
  • Open Access
28 Citations
8,816 Views
16 Pages

Iron Status is Associated with Mood, Cognition, and Functional Ability in Older Adults: A Cross-Sectional Study

  • Carlos Portugal-Nunes,
  • Teresa Costa Castanho,
  • Liliana Amorim,
  • Pedro Silva Moreira,
  • José Mariz,
  • Fernanda Marques,
  • Nuno Sousa,
  • Nadine Correia Santos and
  • Joana Almeida Palha

23 November 2020

Several conditions are risk factors for iron deficiency (ID), some of which are highly prevalent in older individuals. Despite the amount of evidence pointing for a role of ID in cognition, mood and physical functional ability, the research addressin...

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Nutrients - ISSN 2072-6643