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Current Oncology, Volume 28, Issue 1

February 2021 - 98 articles

Cover Story: Lung cancer is the leading cause of cancer-related death in the world, largely due to late stage at diagnosis. Approximately 70% of lung cancer patients in Canada are diagnosed with late-stage disease, emphasizing a need to detect lung cancer earlier. International literature has shown long diagnostic delays in primary care; however, in Canada, little is known about how lung cancer patients move through primary care to get to a respiratory specialist for definitive diagnosis. In this issue, authors identify and describe common lung cancer diagnostic pathways in primary care from first presentation to specialist referral and suggest sources of diagnostic delay combined with potential improvement strategies. View this paper.
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Articles (98)

  • Article
  • Open Access
14 Citations
3,738 Views
9 Pages

Medical and Nonmedical Information during Multidisciplinary Team Meetings in Cancer Care

  • Jessica Wihl,
  • Linn Rosell,
  • Tobias Carlsson,
  • Sara Kinhult,
  • Gert Lindell and
  • Mef Nilbert

23 February 2021

Background: Multidisciplinary team (MDT) meetings provide treatment recommendations based on available information and collective decision-making in teams with complementary professions, disciplines and skills. We aimed to map ancillary medical and n...

  • Article
  • Open Access
25 Citations
5,556 Views
17 Pages

Evolution of Public Health Human Papillomavirus Immunization Programs in Canada

  • Alexandra Goyette,
  • Glorian P. Yen,
  • Voica Racovitan,
  • Parambir Bhangu,
  • Smita Kothari and
  • Eduardo L. Franco

22 February 2021

Background: Since 2007, all Canadian provinces and territories have had a publicly funded program for vaccination against human papillomavirus (HPV) infection. The objective of this study was to describe the evolution of these vaccination programs. M...

  • Case Report
  • Open Access
8 Citations
3,306 Views
4 Pages

Not COVID-19, Don’t Overlook Pneumocystis in Patients on Gefitinib!

  • Jérémy Barben,
  • Valérie Quipourt,
  • Jérémie Vovelle,
  • Alain Putot and
  • Patrick Manckoundia

21 February 2021

An 82-year-old woman treated for advanced lung cancer with gefitinb was admitted to the emergency unit complaining of dyspnea. Chest computed tomography found abnormalities classified as possible diffuse COVID-19 pneumonia. RT-PCR for Sars-Cov-2 was...

  • Article
  • Open Access
7 Citations
3,287 Views
13 Pages

Predictors of Complete Response in Patients with Hepatocellular Carcinoma Treated with Trans-Arterial Radioembolization

  • Yuna Kim,
  • Jae Seung Lee,
  • Hye Won Lee,
  • Beom Kyung Kim,
  • Jun Yong Park,
  • Do Young Kim,
  • Sang Hoon Ahn and
  • Seung Up Kim

21 February 2021

Background: Trans-arterial radioembolization (TARE) has shown promising results in treating hepatocellular carcinoma (HCC). We identified independent predictors of radiological complete response (CR) in patients with intrahepatic HCC who were treated...

  • Article
  • Open Access
10 Citations
3,763 Views
13 Pages

Incidence and Mortality of Prostate Cancer in Canada during 1992–2010

  • François Lagacé,
  • Feras M. Ghazawi,
  • Michelle Le,
  • Evgeny Savin,
  • Andrei Zubarev,
  • Mathieu Powell,
  • Linda Moreau,
  • Denis Sasseville,
  • Ioana Popa and
  • Ivan V. Litvinov

21 February 2021

In Canada, prostate cancer is the most common reportable malignancy in men. We assessed the temporal trends of prostate cancer to gain insight into the geographic incidence and mortality trends of this disease. Three independent population-based canc...

  • Article
  • Open Access
8 Citations
5,218 Views
11 Pages

A Critical Appraisal of Evidence- and Consensus-Based Guidelines for Actinic Keratosis

  • Anja Wessely,
  • Theresa Steeb,
  • Franz Heppt,
  • Annkathrin Hornung,
  • Matthias D. Kaufmann,
  • Elias A. T. Koch,
  • Frédéric Toussaint,
  • Michael Erdmann,
  • Carola Berking and
  • Markus V. Heppt

19 February 2021

Actinic keratoses (AK) are common lesions of the skin that can be effectively treated with several lesion- and field-directed treatments. Clinical practice guidelines assist physicians in choosing the appropriate treatment options for their patients....

  • Article
  • Open Access
9 Citations
3,618 Views
10 Pages

Thoracic Surgeon Impressions of the Impact of the COVID-19 Pandemic on Lung Cancer Care—Lessons from the First Wave in Canada

  • Roy A. Hilzenrat,
  • Shaun A. Deen,
  • John Yee,
  • Kyle A. Grant,
  • Ahmad S. Ashrafi,
  • Shaun Coughlin and
  • Anna L. McGuire

18 February 2021

Background: COVID-19 has invariably changed the way lung cancer surgical care is provided in Canada. Despite relevant management guidelines, the way in which cancer care has been affected has yet to be described for thoracic surgical populations. Rou...

  • Article
  • Open Access
13 Citations
4,626 Views
12 Pages

17 February 2021

Regulators of histone acetylation are promising epigenetic targets for therapy in breast cancer. In this study, we comprehensively analyzed the expression of histone acetylation modulator genes in breast cancer using TCGA data sources. A gene signatu...

  • Case Report
  • Open Access
5 Citations
4,129 Views
10 Pages

16 February 2021

Primary signet ring cell/histiocytoid carcinoma of the eyelid is a rare ocular malignancy and its diagnosis is often delayed. This neoplasm presents as an insidious, diffusely infiltrative mass in the periocular area that later infiltrates the orbit....

  • Article
  • Open Access
12 Citations
4,620 Views
19 Pages

14 February 2021

Understanding the symptom burden trajectory for metastatic breast cancer patients can enable the provision of appropriate supportive care for symptom management. The aim of this study was to describe the longitudinal trajectories of symptom burden fo...

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Curr. Oncol. - ISSN 1718-7729