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Marine Drugs, Volume 14, Issue 5

May 2016 - 22 articles

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Articles (22)

  • Article
  • Open Access
27 Citations
8,697 Views
15 Pages

Time Dependency of Chemodiversity and Biosynthetic Pathways: An LC-MS Metabolomic Study of Marine-Sourced Penicillium

  • Catherine Roullier,
  • Samuel Bertrand,
  • Elodie Blanchet,
  • Mathilde Peigné,
  • Thibaut Robiou du Pont,
  • Yann Guitton,
  • Yves François Pouchus and
  • Olivier Grovel

21 May 2016

This work aimed at studying metabolome variations of marine fungal strains along their growth to highlight the importance of the parameter “time” for new natural products discovery. An untargeted time-scale metabolomic study has been performed on two...

  • Review
  • Open Access
89 Citations
17,544 Views
39 Pages

Marine Invertebrate Metabolites with Anticancer Activities: Solutions to the “Supply Problem”

  • Nelson G. M. Gomes,
  • Ramesh Dasari,
  • Sunena Chandra,
  • Robert Kiss and
  • Alexander Kornienko

21 May 2016

Marine invertebrates provide a rich source of metabolites with anticancer activities and several marine-derived agents have been approved for the treatment of cancer. However, the limited supply of promising anticancer metabolites from their natural...

  • Review
  • Open Access
388 Citations
26,024 Views
16 Pages

Impact of Microalgae-Bacteria Interactions on the Production of Algal Biomass and Associated Compounds

  • Juan Luis Fuentes,
  • Inés Garbayo,
  • María Cuaresma,
  • Zaida Montero,
  • Manuel González-del-Valle and
  • Carlos Vílchez

19 May 2016

A greater insight on the control of the interactions between microalgae and other microorganisms, particularly bacteria, should be useful for enhancing the efficiency of microalgal biomass production and associated valuable compounds. Little attentio...

  • Review
  • Open Access
15 Citations
10,565 Views
20 Pages

19 May 2016

Unlike virtually any other cells in the human body, neurons are tasked with the unique problem of transporting important factors from sites of synthesis at the cell bodies, across enormous distances, along narrow-caliber projections, to distally loca...

  • Article
  • Open Access
38 Citations
7,063 Views
14 Pages

19 May 2016

The lipopolysaccharide binding domain (LBD) in anti-lipopolysaccharide factor (ALF) is the main functional element of ALF, which exhibits antimicrobial activities. Our previous studies show that the peptide LBDv, synthesized based on the modified seq...

  • Review
  • Open Access
117 Citations
15,497 Views
27 Pages

Lipidomic Approaches towards Deciphering Glycolipids from Microalgae as a Reservoir of Bioactive Lipids

  • Elisabete Da Costa,
  • Joana Silva,
  • Sofia Hoffman Mendonça,
  • Maria Helena Abreu and
  • Maria Rosário Domingues

19 May 2016

In recent years, noteworthy research has been performed around lipids from microalgae. Among lipids, glycolipids (GLs) are quite abundant in microalgae and are considered an important source of fatty acids (FAs). GLs are rich in 16- and 18-carbon sat...

  • Review
  • Open Access
131 Citations
17,962 Views
19 Pages

Tiny Microbes with a Big Impact: The Role of Cyanobacteria and Their Metabolites in Shaping Our Future

  • Sophie Mazard,
  • Anahit Penesyan,
  • Martin Ostrowski,
  • Ian T. Paulsen and
  • Suhelen Egan

17 May 2016

Cyanobacteria are among the first microorganisms to have inhabited the Earth. Throughout the last few billion years, they have played a major role in shaping the Earth as the planet we live in, and they continue to play a significant role in our ever...

  • Review
  • Open Access
314 Citations
16,092 Views
31 Pages

“The Good, the Bad and the Ugly” of Chitosans

  • Barbara Bellich,
  • Ilenia D’Agostino,
  • Sabrina Semeraro,
  • Amelia Gamini and
  • Attilio Cesàro

17 May 2016

The objective of this paper is to emphasize the fact that while consistent interest has been paid to the industrial use of chitosan, minor attention has been devoted to spread the knowledge of a good characterization of its physico-chemical propertie...

  • Article
  • Open Access
27 Citations
7,617 Views
18 Pages

The Effect of the Molecular Architecture on the Antioxidant Properties of Chitosan Gallate

  • Chunhua Wu,
  • Liping Wang,
  • Zhongxiang Fang,
  • Yaqin Hu,
  • Shiguo Chen,
  • Tatsuya Sugawara and
  • Xingqian Ye

13 May 2016

To elucidate the structure–antioxidant activity relationships of chitosan gallate (CG), a series of CG derivatives with different degrees of substitution (DS’s) and molecular weights (MWs) were synthesized from chitosan (CS) and gallic acid (GA) via...

  • Feature Paper
  • Review
  • Open Access
96 Citations
16,976 Views
23 Pages

Bacterial Long-Chain Polyunsaturated Fatty Acids: Their Biosynthetic Genes, Functions, and Practical Use

  • Kiyohito Yoshida,
  • Mikako Hashimoto,
  • Ryuji Hori,
  • Takumi Adachi,
  • Hidetoshi Okuyama,
  • Yoshitake Orikasa,
  • Tadashi Nagamine,
  • Satoru Shimizu,
  • Akio Ueno and
  • Naoki Morita

12 May 2016

The nutritional and pharmaceutical values of long-chain polyunsaturated fatty acids (LC-PUFAs) such as arachidonic, eicosapentaenoic and docosahexaenoic acids have been well recognized. These LC-PUFAs are physiologically important compounds in bacter...

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Mar. Drugs - ISSN 1660-3397