Table of Contents
Pharmaceuticals, Volume 11, Issue 3 (September 2018)
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Cover Story (view full-size image) In the era of precision medicine, precision diagnosis is indispensable in oncology. As aptamers [...] Read more. In the era of precision medicine, precision diagnosis is indispensable in oncology. As aptamers show superior target recognition and quick uptake, cancer-specific aptamers have emerged as remarkable detection probes for targeted imaging. Biosensors engineered with fluorogenic aptamers show innovative intracellular imaging in living cells. Aptamers conjugated with fluorophores or gold nanoparticles successfully characterize cancers in tissue imaging. Cancer-specific aptamers labeled with various imaging dyes show satisfactory cancer-specific detection, resulting in the achievement of high-resolution images with low signal-to-noise ratios in vivo in multiple imaging arrays. These advanced molecular imaging approaches demonstrate the value of aptamers in precision diagnostics. View this paper.