Molbank, Volume 2006, Issue 5

In previous works we have shown that hydrazides are highly useful starting materials and intermediates in the synthesis of several heterocyclic compounds^1-3 of potential biological activities.[...]

The quinoline ring systems are important structural units in naturally occurring alkaloids and synthetic analogues with interesting biological activities.[...]

4-phenyl-1,5-benzodiazepine-2-thione are used as starting materials in the synthesis of several heterocyclic compounds for potential biological actvities.[...]

The azomethine 1 was prepared as described elsewhere [1].[...]

In this paper we report the synthesis of 2-((E)-1-(2-((E)-1-(2-hydroxyphenyethylideneamino) phenylamino) ethyl) phenol.In addition to its synthesis we present AM1 and B3LYP/6-31G* calculations to characterize the physical properties of this molecule....

To a solution of 5,5’-diisopropyl-3,3’-bipyrazole 1 [1] (109 mg, 0.5 mmol) in DMSO (2 ml) was added solid potassium tert-butoxide (61 mg, 0.5 mmol) followed by addition of 4-fluoronitrobenzene (70.5 mg, 0.5 mmol) in DMSO (1 ml) through a syringe, acc...

To a solution of 5,5’-diisopropyl-3,3’-bipyrazole 1 [1] (218 mg, 1 mmol) in DMSO (1 ml) was added solid potassium tert-butoxide (112 mg, 1 mmol) followed by addition of ethyle chloroacetate (123 mg, 1 mmol) in DMSO (1 ml) through a syringe[...]

The quinazoline skeleton, when selectively functionalized, is a building block for the preparation of numerous alkaloids and substances capable of exhibiting a wide variety of biological activity [1][...]

The products of aza-type Michael addition, i.e., β-amino carbonyl compounds and their derivatives, are often used as peptide analogs or precursors of optically active amino acids, amino alcohols, diamines, and lactams [1].[...]

The products of aza-type Michael addition, i.e., β-amino carbonyl compounds and their derivatives, are often used as peptide analogs or precursors of optically active amino acids, amino alcohols, diamines, and lactams [1].[...]

The products of aza-type Michael addition, i.e., β-amino carbonyl compounds and their derivatives, are often used as peptide analogs or precursors of optically active amino acids, amino alcohols, diamines, and lactams [1].[...]

The products of aza-type Michael addition, i.e., β-amino carbonyl compounds and their derivatives, are often used as peptide analogs or precursors of optically active amino acids, amino alcohols, diamines, and lactams [1].[...]

In this paper we propose the synthesis of 1-(2,4-dimethoxyphenyl)-4-(4-nitrophenyl)-3- phenoxyazetidin-2-one as a new monocyclic β-lactam. Its structure has been confirmed by IR, ¹H-NMR, ¹³C-NMR and Mass spectroscopic data. In addition to its synthes...

We describe in this work the synthesis of new benzodiazepine derivatives susceptible to possess various pharmacological activities.[...]

We describe in this work the synthesis of new benzodiazepine derivatives susceptible to possess various pharmacological activities.[...]

In the course of our work to prepare inhibitors of the enzyme dihydrofolate reductase, we desired to prepare sulfone analogues of some previously reported sulfides [1, 2].[...]

In the course of our work to prepare inhibitors of the enzyme dihydrofolate reductase, we desired to prepare sulfone analogues of some similar sulfides [1, 2].[...]

In the course of our work to prepare inhibitors of the enzyme dihydrofolate reductase, we desired to prepare sulfone analogues of some previously reported sulfides [1, 2].[...]

In the course of our work to prepare inhibitors of the enzyme dihydrofolate reductase, we desired to prepare sulfone analogues of some similar sulfides [1, 2].[...]