Molbank, Volume 2006, Issue 5

To a solution of 5,5’-diisopropyl-3,3’-bipyrazole 1 [1] (218 mg, 1 mmol) in DMSO (1 ml) was added solid potassium tert-butoxide (112 mg, 1 mmol) followed by addition of ethyle chloroacetate (123 mg, 1 mmol) in DMSO (1 ml) through a syringe[...]

The quinazoline skeleton, when selectively functionalized, is a building block for the preparation of numerous alkaloids and substances capable of exhibiting a wide variety of biological activity [1][...]

The products of aza-type Michael addition, i.e., β-amino carbonyl compounds and their derivatives, are often used as peptide analogs or precursors of optically active amino acids, amino alcohols, diamines, and lactams [1].[...]

The products of aza-type Michael addition, i.e., β-amino carbonyl compounds and their derivatives, are often used as peptide analogs or precursors of optically active amino acids, amino alcohols, diamines, and lactams [1].[...]

The products of aza-type Michael addition, i.e., β-amino carbonyl compounds and their derivatives, are often used as peptide analogs or precursors of optically active amino acids, amino alcohols, diamines, and lactams [1].[...]

The products of aza-type Michael addition, i.e., β-amino carbonyl compounds and their derivatives, are often used as peptide analogs or precursors of optically active amino acids, amino alcohols, diamines, and lactams [1].[...]

In this paper we propose the synthesis of 1-(2,4-dimethoxyphenyl)-4-(4-nitrophenyl)-3- phenoxyazetidin-2-one as a new monocyclic β-lactam. Its structure has been confirmed by IR, 1H-NMR, 13C-NMR and Mass spectroscopic data. In addition to its synthes...

We describe in this work the synthesis of new benzodiazepine derivatives susceptible to possess various pharmacological activities.[...]

We describe in this work the synthesis of new benzodiazepine derivatives susceptible to possess various pharmacological activities.[...]

In the course of our work to prepare inhibitors of the enzyme dihydrofolate reductase, we desired to prepare sulfone analogues of some previously reported sulfides [1, 2].[...]