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Molecules, Volume 24, Issue 9

May-1 2019 - 201 articles

Cover Story: 4-Hydroxycyanobenzene (4HCB) is a dipolar molecule with both π–π and hydrogen-bonding interactions in the solid state and it exhibits semiconductor properties. We investigated the high-pressure behaviour of 4HCB using single-crystal diffraction with two loadings using helium and neon as pressure-transmitting media. Our study highlights how the molecular packing and π–π interactions evolve with pressure as well as with He insertion. View this paper.
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Articles (201)

  • Article
  • Open Access
14 Citations
4,518 Views
16 Pages

A simple, rapid and novel method for the detection of residues of thiamphenicol (TAP), florfenicol (FF) and its metabolite, florfenicol amine (FFA), in poultry eggs by ultra-performance liquid chromatography-fluorescence detection (UPLC-FLD) was deve...

  • Article
  • Open Access
17 Citations
4,334 Views
18 Pages

Naodesheng (NDS) is a widely used traditional Chinese medicine (TCM) prescription for the treatment of ischemic stroke. A combination of 10 components is derived from NDS. They are: Notoginsenoside R1, ginsenoside Rg1, ginsenoside b1, ginsenoside Rd,...

  • Article
  • Open Access
9 Citations
3,871 Views
13 Pages

An effective and friendly method was developed for the production of reducing sugars (RS) from the hydrolysis of cellulose over the solid catalyst of Ca-montmorillonite (Mt) grafted by non-acidic ionic liquid (Mt-IL) in water. The effect of mass rati...

  • Article
  • Open Access
4 Citations
4,896 Views
17 Pages

Autophagy-Related Proteins GABARAP and LC3B Label Structures of Similar Size but Different Shape in Super-Resolution Imaging

  • Iman Abdollahzadeh,
  • Johnny Hendriks,
  • Julia L. Sanwald,
  • Indra M. Simons,
  • Silke Hoffmann,
  • Oliver H. Weiergräber,
  • Dieter Willbold and
  • Thomas Gensch

Subcellular structures containing autophagy-related proteins of the Atg8 protein family have been investigated with conventional wide-field fluorescence and single molecule localisation microscopy. Fusion proteins of GABARAP and LC3B, respectively, w...

  • Article
  • Open Access
25 Citations
4,870 Views
15 Pages

Lentinus edodes, whose polysaccharides possess diverse bioactivities, commonly grows on hardwood sawdust composed of hemicellulose, lignin and cellulose. In this study the effect of hemicellulose and lignin on the growth of mycelia, as well as the ph...

  • Article
  • Open Access
59 Citations
6,807 Views
14 Pages

Antiviral Effects of Houttuynia cordata Polysaccharide Extract on Murine Norovirus-1 (MNV-1)—A Human Norovirus Surrogate

  • Dongqing Cheng,
  • Liang Sun,
  • Songyan Zou,
  • Jiang Chen,
  • Haiyan Mao,
  • Yanjun Zhang,
  • Ningbo Liao and
  • Ronghua Zhang

Houttuynia cordata is an herbal plant rich in polysaccharides and with several pharmacological activities. Human noroviruses (HuNoVs) are the most common cause of foodborne viral gastroenteritis throughout the world. In this study, H. cordata polysac...

  • Review
  • Open Access
23 Citations
8,741 Views
35 Pages

Terrestrial Microorganisms: Cell Factories of Bioactive Molecules with Skin Protecting Applications

  • Laure-Anne Peyrat,
  • Nikolaos Tsafantakis,
  • Katerina Georgousaki,
  • Jamal Ouazzani,
  • Olga Genilloud,
  • Ioannis P. Trougakos and
  • Nikolas Fokialakis

It is well known that terrestrial environments host an immense microbial biodiversity. Exposed to different types of stress, such as UV radiation, temperature fluctuations, water availability and the inter- / intra-specific competition for resources,...

  • Article
  • Open Access
28 Citations
4,516 Views
18 Pages

As calcium signal sensors, calcium-dependent protein kinases (CPKs) play vital roles in stimulating the production of secondary metabolites to participate in plant development and response to environmental stress. However, investigations of the Glycy...

  • Article
  • Open Access
36 Citations
4,652 Views
14 Pages

The wax apple (Syzygium samarangense) is traditionally employed as an antibacterial and immunostimulant drug in traditional medicine. This plant is rich in different flavonoids and tannins. In this study, we isolated two compounds from S. samarangens...

  • Article
  • Open Access
144 Citations
7,704 Views
17 Pages

The Role of Astragaloside IV against Cerebral Ischemia/Reperfusion Injury: Suppression of Apoptosis via Promotion of P62-LC3-Autophagy

  • Yi Zhang,
  • Ying Zhang,
  • Xiao-fei Jin,
  • Xiao-hong Zhou,
  • Xian-hui Dong,
  • Wen-tao Yu and
  • Wei-juan Gao

Background: Ischemia/reperfusion (I/R) caused by ischemic stroke treatments leads to brain injury, and autophagy plays a role in the pathology. Astragaloside IV is a potential neuroprotectant, but its underlying mechanism on cerebral I/R injury needs...

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Molecules - ISSN 1420-3049Creative Common CC BY license