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18 Results Found

  • Article
  • Open Access
24 Citations
5,731 Views
11 Pages

Multicentre Study of Chronic Wounds Point Prevalence in Primary Health Care in the Southern Metropolitan Area of Barcelona

  • Miguel Ángel Díaz-Herrera,
  • José Ramón Martínez-Riera,
  • José Verdú-Soriano,
  • Raúl Miguel Capillas-Pérez,
  • Carme Pont-García,
  • Silvia Tenllado-Pérez,
  • Oriol Cunillera-Puértolas,
  • Miriam Berenguer-Pérez and
  • Vicente Gea-Caballero

16 February 2021

Background: Chronic wounds give rise to major costs and resource consumption in health care systems, due to their protracted healing time. Incidence and prevalence data are scarce or nonexistent in community settings. Objective: The aim of the presen...

  • Article
  • Open Access
3 Citations
3,506 Views
10 Pages

The progression of clinical manifestations of lower-limb varicose veins remains unclear. This study investigated changes in lower-limb venous blood flow using phase-contrast magnetic resonance angiography. Data were collected on veins from 141 legs....

  • Review
  • Open Access
30 Citations
7,032 Views
13 Pages

Molecular Determinants of Chronic Venous Disease: A Comprehensive Review

  • Davide Costa,
  • Michele Andreucci,
  • Nicola Ielapi,
  • Giuseppe Filiberto Serraino,
  • Pasquale Mastroroberto,
  • Umberto Marcello Bracale and
  • Raffaele Serra

18 January 2023

Chronic Venous Disease (CVD) refers to several pathological and hemodynamic alterations of the veins of lower limbs causing a wide range of symptoms and signs with a high prevalence in the general population and with disabling consequences in the mos...

  • Article
  • Open Access
5 Citations
6,170 Views
13 Pages

Effects of Oral Nutritional Supplementation on Patients with Venous Ulcers: A Clinical Trial

  • Paulla Guimarães Melo,
  • João Felipe Mota,
  • Cynthia Assis de Barros Nunes,
  • Suelen Gomes Malaquias,
  • Alexandre Siqueira Guedes Coelho,
  • José Verdú Soriano and
  • Maria Márcia Bachion

26 September 2022

Background: The dosage and safety of nutritional supplements for patients with venous ulcers are still not well established. Aim: To evaluate the effects of a high calorie, high protein, arginine-, zinc-, and vitamins A, C, and E-enriched nutritional...

  • Article
  • Open Access
2,110 Views
12 Pages

Correlation between Generic and Disease-Specific Quality of Life Questionnaires in Patients with Venous Ulcerations: A Cross-Sectional Study Carried out in a Primary Health Care Setting in Brazil

  • Dalyanna Mildred de Oliveira Viana Pereira,
  • Adriana Catarina de Souza Oliveira,
  • Severino Azevedo de Oliveira Júnior,
  • Maria Angélica Gomes Jacinto,
  • Alessandra Justino Dionísio,
  • Alana Ellen Oliveira Lima,
  • Bruno Araújo da Silva Dantas,
  • Silvana Loana de Oliveira Sousa,
  • Carmelo Sergio Gómez Martínez and
  • Gilson de Vasconcelos Torres

Venous Ulcers (VU) are a serious health problem that affect the Quality of Life (QoL). They are evaluated by many different scales in the literature. We aimed to analyze the correlation between the Medical Outcomes Short-Form Health QoL (SF-36) and C...

  • Article
  • Open Access
389 Views
20 Pages

Multilayer Perceptron Artificial Neural Network to Support Nurses’ Decision-Making on Topical Therapies for Venous Ulcers: Construction, Validation, and Evaluation

  • Simone Karine da Costa Mesquita,
  • Luana Souza Freitas,
  • Isabelle Pereira da Silva,
  • Anna Alice Carmo Gonçalves,
  • Alcides Viana de Lima Neto,
  • Carlos Alberto de Albuquerque Silva,
  • Nielsen Castelo Damasceno Dantas,
  • Rhayssa de Oliveira e Araújo and
  • Isabelle Katherinne Fernandes Costa

Background: Due to the complexity of venous ulcer treatment, the role of nurses is critical, and artificial intelligence, particularly artificial neural networks of the Multilayer Perceptron type, can be effective tools that support professionals wit...

  • Review
  • Open Access
1,230 Views
13 Pages

Venous Manifestations of Gastric Cancer: Bilateral Varicose Veins as a Rare Initial Presentation—A Narrative Review

  • Anna Laura Maiozzi,
  • Filomena Botta,
  • Silvia Maccioni,
  • Livia Stanga,
  • Lucretia Marin-Bancila,
  • Ciprian Ilie Rosca,
  • Anca Dinu,
  • Abhinav Sharma and
  • Nilima Rajpal Kundnani

Background: Varicose veins (VVs) are an overlying manifestation of chronic venous disease, commonly occurring in the lower extremities. While typically linked to primary venous insufficiency, they can occasionally be secondary to systemic disease, e....

  • Article
  • Open Access
3 Citations
2,460 Views
16 Pages

Local and Systemic Endothelial Damage in Patients with CEAP C2 Chronic Venous Insufficiency: Role of Mesoglycan

  • Angelo Santoliquido,
  • Claudia Carnuccio,
  • Luca Santoro,
  • Angela Di Giorgio,
  • Alessia D'Alessandro,
  • Francesca Romana Ponziani,
  • Flavia Angelini,
  • Marcello Izzo and
  • Antonio Nesci

Chronic venous disease (CVD) involves complex pathophysiological mechanisms, particularly an imbalance between matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs), contributing to venous remodeling and varicosities. Elevated MMP-2 an...

  • Article
  • Open Access
9 Citations
3,004 Views
13 Pages

Radiofrequency Thermal Ablation for the Treatment of Chronic Insufficiency of the Saphenous Vein—A Comparative Retrospective Study

  • Octavian Andercou,
  • Bogdan Stancu,
  • Horațiu Flaviu Coman,
  • Beatrix Cucuruz,
  • Thomas Noppeney and
  • Dorin Marian

Objectives: The broad spectrum of chronic venous disease encompasses varicose veins, edema, hyperpigmentation and venous ulcers. Radiofrequency thermal ablation is indicated for the treatment of superficial venous reflux of the lower limb. Our resear...

  • Systematic Review
  • Open Access
4 Citations
4,316 Views
27 Pages

Daily Duration of Compression Treatment in Chronic Venous Disease Patients: A Systematic Review

  • Sevara Mirakhmedova,
  • Amirkhan Amirkhanov,
  • Evgenii Seliverstov,
  • Oksana Efremova and
  • Igor Zolotukhin

27 August 2023

Background: There are no data on the daily regimen of compression therapy in patients with chronic venous disease. This systematic review aimed to establish the optimal daily duration of compression treatment. Methods: A systematic search of CENTRAL...

  • Review
  • Open Access
107 Citations
26,463 Views
16 Pages

Centella asiatica and Its Metabolite Asiatic Acid: Wound Healing Effects and Therapeutic Potential

  • Lúcio Ricardo Leite Diniz,
  • Leonardo Luiz Calado,
  • Allana Brunna Sucupira Duarte and
  • Damião Pergentino de Sousa

14 February 2023

An intense effort has been focused on new therapeutic approaches and the development of technologies for more efficient and rapid wound healing. The research for plants used for long time in traditional medicine in the treatment of wound has become a...

  • Feature Paper
  • Article
  • Open Access
54 Citations
10,899 Views
10 Pages

Design, Manufacture and Testing of Capacitive Pressure Sensors for Low-Pressure Measurement Ranges

  • Vasileios Mitrakos,
  • Lisa Macintyre,
  • Fiona C. Denison,
  • Philip J.W. Hands and
  • Marc P.Y. Desmulliez

1 February 2017

This article presents the design, manufacture and testing of a capacitive pressure sensor with a high, tunable performance to low compressive loads (<10 kPa) and a resolution of less than 0.5 kPa. Such a performance is required for the monitoring...

  • Review
  • Open Access
149 Citations
26,933 Views
42 Pages

Understanding Chronic Venous Disease: A Critical Overview of Its Pathophysiology and Medical Management

  • Miguel A. Ortega,
  • Oscar Fraile-Martínez,
  • Cielo García-Montero,
  • Miguel A. Álvarez-Mon,
  • Chen Chaowen,
  • Fernando Ruiz-Grande,
  • Leonel Pekarek,
  • Jorge Monserrat,
  • Angel Asúnsolo and
  • Julia Bujan
  • + 2 authors

22 July 2021

Chronic venous disease (CVD) is a multifactorial condition affecting an important percentage of the global population. It ranges from mild clinical signs, such as telangiectasias or reticular veins, to severe manifestations, such as venous ulceration...

  • Article
  • Open Access
21 Citations
4,084 Views
23 Pages

Dysregulations of MicroRNA and Gene Expression in Chronic Venous Disease

  • Daniel P. Zalewski,
  • Karol P. Ruszel,
  • Andrzej Stępniewski,
  • Dariusz Gałkowski,
  • Jacek Bogucki,
  • Łukasz Komsta,
  • Przemysław Kołodziej,
  • Paulina Chmiel,
  • Tomasz Zubilewicz and
  • Anna Bogucka-Kocka
  • + 2 authors

25 April 2020

Chronic venous disease (CVD) is a vascular disease of lower limbs with high prevalence worldwide. Pathologic features include varicose veins, venous valves dysfunction and skin ulceration resulting from dysfunction of cell proliferation, apoptosis an...

  • Article
  • Open Access
13 Citations
5,895 Views
13 Pages

Objectives: Venous diseases in the lower extremities long lacked an objective diagnostic tool prior to the advent of the triggered angiography non-contrast-enhanced (TRANCE) technique. Methods: An observational study with retrospective data analysis....

  • Article
  • Open Access
2 Citations
2,317 Views
20 Pages

Omics Data Integration Uncovers mRNA-miRNA Interaction Regions in Genes Associated with Chronic Venous Insufficiency

  • Fatma Sarı-Tunel,
  • Ayse Demirkan,
  • Burcak Vural,
  • Cenk Eray Yıldız and
  • Evrim Komurcu-Bayrak

31 December 2024

Background/Objectives: Chronic venous insufficiency (CVI), a chronic vascular dysfunction, is a common health problem that causes serious complications such as painful varicose veins and even skin ulcers. Identifying the underlying genetic and epigen...

  • Review
  • Open Access
238 Citations
37,317 Views
33 Pages

Why Venous Leg Ulcers Have Difficulty Healing: Overview on Pathophysiology, Clinical Consequences, and Treatment

  • Joseph D. Raffetto,
  • Daniela Ligi,
  • Rosanna Maniscalco,
  • Raouf A. Khalil and
  • Ferdinando Mannello

24 December 2020

Venous leg ulcers (VLUs) are one of the most common ulcers of the lower extremity. VLU affects many individuals worldwide, could pose a significant socioeconomic burden to the healthcare system, and has major psychological and physical impacts on the...