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Open AccessArticle

Novel Diagnostic Options without Contrast Media or Radiation: Triggered Angiography Non-Contrast-Enhanced Sequence Magnetic Resonance Imaging in Treating Different Leg Venous Diseases

1
Institute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan
2
Department of Diagnostic Radiology, Chang Gung Memorial Hospital, Chiayi Branch, Chiayi 61363, Taiwan
3
College of Medicine, Chang Gung University, Taoyuan 333, Taiwan
4
Division of Thoracic and Cardiovascular Surgery, ChiaYi Chang Gung Memorial Hospital, Chiayi and Chang Gung University, College of Medicine, Taoyuan 61363, Taiwan
5
Wound and Vascular Center, Chang Gung Memorial Hospital, Chiayi 61363, Taiwan
6
Institute of Imaging and Biomedical Photonics, National Chiao Tung University, Tainan 71150, Taiwan
*
Author to whom correspondence should be addressed.
Diagnostics 2020, 10(6), 355; https://doi.org/10.3390/diagnostics10060355
Received: 13 May 2020 / Revised: 23 May 2020 / Accepted: 27 May 2020 / Published: 29 May 2020
(This article belongs to the Special Issue Advanced Techniques in Body Magnetic Resonance Imaging)
Objectives: Venous diseases in the lower extremities long lacked an objective diagnostic tool prior to the advent of the triggered angiography non-contrast-enhanced (TRANCE) technique. Methods: An observational study with retrospective data analysis. Materials: Between April 2017 and June 2019, 66 patients were evaluated for venous diseases through TRANCE-magnetic resonance imaging (MRI) and were grouped according to whether they had occlusive venous (OV) disease, a static venous ulcer (SU), or symptomatic varicose veins (VV). The clinical appliance of TRANCE-MRI was analysed by groups. Results: In total, 63 patients completed the study. TRANCE-MRI could identify venous thrombosis, including that of the abdominal and pelvic vessels, and it enabled the timely treatment of underlying diseases in patients with OV disease. TRANCE-MRI was statistically compared with the duplex scan, the gold standard to exclude deep vein thrombosis (DVT) in the legs, with regard to their abilities to detect venous thrombosis by using Cohen’s kappa coefficient at a compatible value of 0.711. It could provide the occlusion degree of the peripheral artery for treating an SU. Finally, TRANCE-MRI can be used to outline all collateral veins and occult thrombi before treating symptomatic or recurrent VV to ensure a perfect surgical plan and to avoid complications. Conclusions: TRANCE-MRI is an innovative tool in the treatment of versatile venous pathology in the lower extremities and is widely used for vascular diseases in our institution. View Full-Text
Keywords: MRI; non-contrast; venography; TRANCE; static ulcer; venous disease MRI; non-contrast; venography; TRANCE; static ulcer; venous disease
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Chen, C.-W.; Tseng, Y.-H.; Lin, C.-C.; Kao, C.-C.; Wong, M.Y.; Lin, B.-S.; Huang, Y.-K. Novel Diagnostic Options without Contrast Media or Radiation: Triggered Angiography Non-Contrast-Enhanced Sequence Magnetic Resonance Imaging in Treating Different Leg Venous Diseases. Diagnostics 2020, 10, 355.

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