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17 Results Found

  • Article
  • Open Access
1,440 Views
44 Pages

MetaFFI-Multilingual Indirect Interoperability System

  • Tsvi Cherny-Shahar and
  • Amiram Yehudai

26 August 2025

The development of software applications using multiple programming languages has increased in recent years, as it allows the selection of the most suitable language and runtime for each component of the system and the integration of third-party libr...

  • Article
  • Open Access
1,823 Views
14 Pages

18 December 2023

We reported a molecular dynamics (MD) simulation study of an advancing pure Al(100)/melt interface that encounters a foreign immiscible liquid Pb cylindrical nano-inclusion. When the advancing interface approaches the inclusion, the interface may eng...

  • Review
  • Open Access
601 Citations
42,334 Views
31 Pages

Macrophages, Foreign Body Giant Cells and Their Response to Implantable Biomaterials

  • Zeeshan Sheikh,
  • Patricia J. Brooks,
  • Oriyah Barzilay,
  • Noah Fine and
  • Michael Glogauer

28 August 2015

All biomaterials, when implanted in vivo, elicit cellular and tissue responses. These responses include the inflammatory and wound healing responses, foreign body reactions, and fibrous encapsulation of the implanted materials. Macrophages are myeloi...

  • Article
  • Open Access
3 Citations
2,703 Views
15 Pages

12 March 2021

The foreign body reaction to neuronal electrode implants limits potential applications as well as the therapeutic period. Developments in the basic electrode design might improve the tissue compatibility and thereby reduce the foreign body reaction....

  • Review
  • Open Access
20 Citations
9,199 Views
14 Pages

14 June 2019

Limb amputation is a major cause of disability in our community, for which motorised prosthetic devices offer a return to function and independence. With the commercialisation and increasing availability of advanced motorised prosthetic technologies,...

  • Review
  • Open Access
6 Citations
4,549 Views
19 Pages

Large Animal Studies to Reduce the Foreign Body Reaction in Brain–Computer Interfaces: A Systematic Review

  • Shan Yasin Mian,
  • Jonathan Roy Honey,
  • Alejandro Carnicer-Lombarte and
  • Damiano Giuseppe Barone

16 August 2021

Brain–computer interfaces (BCI) are reliant on the interface between electrodes and neurons to function. The foreign body reaction (FBR) that occurs in response to electrodes in the brain alters this interface and may pollute detected signals, ultima...

  • Review
  • Open Access
32 Citations
7,888 Views
27 Pages

23 August 2021

Neural electrodes are essential for nerve signal recording, neurostimulation, neuroprosthetics and neuroregeneration, which are critical for the advancement of brain science and the establishment of the next-generation brain–electronic interface, cen...

  • Article
  • Open Access
1 Citations
6,245 Views
31 Pages

Efficient Data Exchange between WebAssembly Modules

  • Lucas Silva,
  • José Metrôlho and
  • Fernando Ribeiro

20 September 2024

In the past two decades, there has been a noticeable decoupling of machines and operating systems. In this context, WebAssembly has emerged as a promising alternative to traditional virtual machines. Originally designed for execution in web browsers,...

  • Review
  • Open Access
579 Citations
21,724 Views
42 Pages

Biomaterials: Foreign Bodies or Tuners for the Immune Response?

  • Erminia Mariani,
  • Gina Lisignoli,
  • Rosa Maria Borzì and
  • Lia Pulsatelli

The perspectives of regenerative medicine are still severely hampered by the host response to biomaterial implantation, despite the robustness of technologies that hold the promise to recover the functionality of damaged organs and tissues. In this s...

  • Review
  • Open Access
48 Citations
12,622 Views
20 Pages

Neural Probes for Chronic Applications

  • Geon Kook,
  • Sung Woo Lee,
  • Hee Chul Lee,
  • Il-Joo Cho and
  • Hyunjoo Jenny Lee

2 October 2016

Developed over approximately half a century, neural probe technology is now a mature technology in terms of its fabrication technology and serves as a practical alternative to the traditional microwires for extracellular recording. Through extensive...

  • Article
  • Open Access
5 Citations
1,869 Views
14 Pages

Oxygenated VOC Detection Using SnO2 Nanoparticles with Uniformly Dispersed Bi2O3

  • Haoyue Yang,
  • Koichi Suematsu,
  • Felipe Hiroshi Mashiba,
  • Ken Watanabe and
  • Kengo Shimanoe

18 December 2024

Bi2O3 particles are introduced as foreign additives onto SnO2 nanoparticles (NPs) surfaces for the efficient detection of oxygenated volatile organic compounds (VOCs). Bi2O3-loaded SnO2 materials are prepared via the impregnation method followed by c...

  • Article
  • Open Access
7 Citations
2,853 Views
14 Pages

11 November 2021

Articular cartilage, which is a white transparent tissue with 1–2 mm thickness, is located in the interface between the two hard bones. The main functions of articular cartilage are stress transmission, absorption, and friction reduction. The cartila...

  • Review
  • Open Access
6 Citations
3,077 Views
19 Pages

11 February 2025

Many polyunsaturated fatty acids within cells exhibit diverse physiological functions. Particularly, arachidonic acid is the precursor of highly bioactive prostaglandins and leukotrienes, which are pro-inflammatory mediators. However, polyunsaturated...

  • Article
  • Open Access
186 Views
27 Pages

Failure Mechanism and Biomimetic Wiping Self-Cleaning Design of Micro-Current Snap-Action Limit Switches for Marine Environments

  • Yuhang Zhong,
  • Xiaolong Zhao,
  • Chengfei Zhang,
  • Yuliang Teng,
  • Zhuxin Zhang and
  • Dingxuan Zhao

2 February 2026

In marine hot–humid and salt spray environments, shipborne snap-action limit switches operating under micro-current loads are prone to triggering failures caused by the accumulation of heterogeneous films on electrical contact interfaces, which...

  • Feature Paper
  • Review
  • Open Access
51 Citations
7,815 Views
21 Pages

22 February 2022

Silicon carbide (SiC) is a highly robust semiconductor material that has the potential to revolutionize implantable medical devices for human healthcare, such as biosensors and neuro-implants, to enable advanced biomedical therapeutic applications fo...

  • Review
  • Open Access
1 Citations
4,651 Views
11 Pages

Exploring the Potential of Plant-Based CTB-INS Oral Vaccines in Treating Type 1 Diabetes

  • Jacques C. Mbongue,
  • Elaine Vanterpool and
  • William H. R. Langridge

1 June 2023

The 19th century saw the development of vaccines, which were biological preparations designed to enhance immunity against specific diseases. Edible vaccines function by stimulating both systemic and mucosal immune responses against foreign pathogens,...

  • Communication
  • Open Access
17 Citations
4,521 Views
18 Pages

A Soft Zwitterionic Hydrogel as Potential Coating on a Polyimide Surface to Reduce Foreign Body Reaction to Intraneural Electrodes

  • Manuele Gori,
  • Sara Maria Giannitelli,
  • Gianluca Vadalà,
  • Rocco Papalia,
  • Loredana Zollo,
  • Massimo Sanchez,
  • Marcella Trombetta,
  • Alberto Rainer,
  • Giovanni Di Pino and
  • Vincenzo Denaro

Invasive intraneural electrodes can control advanced neural-interfaced prostheses in human amputees. Nevertheless, in chronic implants, the progressive formation of a fibrotic capsule can gradually isolate the electrode surface from the surrounding t...